Anti-TBX1 antibody ab18530 from Abcam

Product Specs
ItemAnti-TBX1 antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab18530
Antibody TypePrimary
ApplicationsImmunocytochemistry/ Immunofluorescence, Western blot
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Quantity100 UG
Conjugate/TagUnconjugated
Concentration0.5 mg/ml
Gene Nametbx1
ReactivityHuman
TargetTBX1

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract developmentCardiovascular researchMay 22, 2023Zhou C, Häneke T, Rohner E, Sohlmér J, Kameneva P, Artemov A, Adameyko I, Sahara M.anti-RXRα (Cell Signaling Technology, 3085S); anti-STRA6 (Novus, NBP1-83719); and anti-TBX1 (Abcam, ab18530) (see Supplementary material online, Table S1). After washing with TBS-T, membranes were incubated with

(2) A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndromeDisease Models & MechanismsSeptember 1, 2022Gabriella Lania, Monica Franzese, Noritaka Noritaka, Marchesa Bilio, Gemma Flore, Annalaura Russo, Erika D'Agostino, Claudia Angelini, Robert G. Kelly, Antonio BaldiniBank, clone 39.4D5, diluted 1:100); anti-CRE (Millipore, 69050-3, diluted 1:1000); anti-TBX1 (Abcam, ab18530, diluted 1:100). Image acquisition Most images were acquired using a Nikon A1 laser scanning confocal

(3) Variants in a cis-regulatory element of TBX1 in conotruncal heart defect patients impair GATA6-mediated transactivationOrphanet Journal of Rare DiseasesDecember 1, 2021Xuechao Jiang, Tingting Li, Sijie Liu, Qihua Fu, Fen Li, Sun Chen, Kun Sun, Rang Xu, Yuejuan Xuroom temperature, followed by incubating with rabbit polyclonal antibody against TBX1 (Abcam Inc., ab18530, Cambridge, UK) or GATA6 (Santa Cruz Biotechnology Inc., sc-9055, USA) overnight at 4℃. Next, the secondary

(4) EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endodermDisease Models & MechanismsMarch 1, 2021Cinzia Caprio, Gabriella Lania, Marchesa Bilio, Rosa Ferrentino, Li Chen, Antonio Baldini

(5) TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 SignalingInternational Journal of Molecular SciencesJanuary 17, 2020Cinzia Caprio et al.into four μm sections and subjected to immunofluorescence, by using an anti-TBX1 antibody (Abcam, #ab18530, 1: 100), anti-E-Cadherin antibody (BD Biosciences, #610182, 1:200) anti-Ki67 antibody (BD Biosciences,

(6) Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 MacrophagesMedicines (Basel, Switzerland)January 31, 2019Miller CN, Samuels JS, Azhar Y, Parmar A, Shashidharamurthy R, Rayalam S.dilution), anti-liver-arginase-1 (ab124917; 1/2000 dilution), and anti-TBX1 (t-box transcription factor 1; ab18530; 1/2000 dilution) antibodies were from Abcam (Cambridge, United Kingdom). Anti-β-3AR (β-3 adrenergic

(7) A loss-of-function mutation p.T52S in RIPPLY3 is a potential predisposing genetic risk factor for Chinese Han conotruncal heart defect patients without the 22q11.2 deletion/duplicationJournal of Translational MedicineDecember 1, 2018Nanchao Hong et al.

(8) MicroRNA-451a acts as tumor suppressor in cutaneous basal cell carcinomaMolecular Genetics & Genomic MedicineNovember 1, 2018Hui Sun, Pingdong Jiangaccording to the manufacturer's instruction. 2.5 Antibodies and reagents Antibodies against human Tbx1 (ab18530) and Gapdh (ab9485) were from Abcam. miRNA‐451a mimic and its scramble control were ordered from Sigma‐Aldrich.

(9) Clinical study of prenatal ultrasonography combined with T‑box transcription factor 1 as a biomarker for the diagnosis of congenital heart diseaseMolecular Medicine ReportsMarch 14, 2018Bingcheng Guo, Jing Xiao, Long Li, Shuanglong Wang, Lijuan Wang, Shuyong LiuInc.)/PBS with Tween-20 (PBST) for 2 h at 37˚C, the membrane was incubated with anti‑TBX1 (cat. no. ab18530; Abcam, Cambridge, MA, USA) or anti‑β‑actin (cat. no. ab8227; Abcam) primary antibodies (1:2,000) at

(10) Tissue-specific roles for Sonic hedgehog signaling in establishing thymus and parathyroid organ fateDevelopmentJuly 6, 2016Virginia E. Bain, Julie Gordon, John D. O'Neil, Isaias Ramos, Ellen R. Richie, Nancy R. ManleySanta Cruz sc-23566, G-20), rabbit anti-GCM2 (1:200, Abcam ab64723), rabbit anti-TBX1 (1:100, Abcam ab18530), rabbit anti-cleaved caspase 3 (1:200, Cell Signaling #9661), rat anti-BrdU (1:10, AbD Serotec OBT0030CX)

(11) Rebalancing gene haploinsufficiency in vivo by targeting chromatinNature communicationsJune 3, 2016Fulcoli FG, Franzese M, Liu X, Zhang Z, Angelini C, Baldini A.addition of 1 mM EGTA. The immunoblotting detections were performed with the anti Tbx1 antibody (Abcam, #ab18530; 1:1,000), anti Lamin-B (Santa Cruz, #sc-6216; 1:1,000) and anti-Histone H3 antibody (Abcam, #ab1791;

(12) p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndromeProceedings of the National Academy of Sciences of the United States of AmericaSeptember 16, 2014Cinzia Caprio, Antonio Baldini

(13) Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesisDevelopment (Cambridge, England)August 1, 2014Reeh KA, Cardenas KT, Bain VE, Liu Z, Laurent M, Manley NR, Richie ER.3865-3878. 2957 DEVELOPMENT Primary antibodies used were goat anti-Foxn1 (1:200, Santa Cruz, G-20), rabbit anti-Tbx1 (1:100, Abcam, ab18530), rabbit anti-Gcm2 (1:200, Abcam, ab64723), rabbit anti-Foxg1 (1:50, Abcam, ab18259), rat anti-BrdU

(14) Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactorBiomaterialsJanuary 1, 2014Ghaedi M, Mendez JJ, Bove PF, Sivarapatna A, Raredon MS, Niklason LE.IHC, FC" T1α,Monoclonal,"Abcam (Cat# ab10288, Lot# GR47830-3)",IHC AQ5,Rabbit polyclonal,Abcam(Cat# ab18530),ICC Caveolin-1,Rabbit monoclonal,"Millipore(Cat#MAB4381, Lot# LV1512392)",ICC CD54-PE,Mouse monoclonal,"BD

(15) Tbx1 regulates brain vascularizationHuman molecular geneticsJanuary 1, 2014Cioffi S, Martucciello S, Fulcoli FG, Bilio M, Ferrentino R, Nusco E, Illingworth E.

(16) Tbx1 Genetically Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein Inhibitor Smad7 During Great Vessel RemodelingCirculation ResearchJanuary 4, 2013Irinna Papangeli, Peter J. Scamblerchromatin immunoprecipitation (ChIP) experiment, which was performed using 10 mg of TBX1 antibody (ab18530, Abcam) and 10 mg of rabbit IgG antibody (ab46540, Abcam) as negative control, as previously described.33

(17) Tbx1 is a negative modulator of Mef2cHuman molecular geneticsJune 1, 2012Luna Simona Pane, Zhen Zhang, Rosa Ferrentino, Tuong Huynh, Luisa Cutillo, Antonio Baldini

(18) Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with the BAF Chromatin Remodeling Complex and Regulates Wnt5aPLoS GeneticsMarch 15, 2012Li Chen, Filomena Gabriella Fulcoli, Rosa Ferrentino, Stefania Martucciello, Elizabeth A. Illingworth, Antonio BaldiniHercules, CA). Approximately 100 µg of nuclear extracts were incubated with an anti Tbx1 antibody (Abcam, #ab18530) or Baf60a antibody (BD Biosciences, #611728) or rabbit/mouse IgG (Santa Cruz Biotechnology, #2027)

(19) Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse modelHuman molecular geneticsDecember 15, 2011Takeshi Hiramoto, Gina Kang, Go Suzuki, Yasushi Satoh, Raju Kucherlapati, Yasuhiro Watanabe, Noboru Hiroi

(20) Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cellsNature BiotechnologyMarch 1, 2011Michael D Green, Antonia Chen, Maria-Cristina Nostro, Sunita L d'Souza, Christoph Schaniel, Ihor R Lemischka, Valerie Gouon-Evans, Gordon Keller, Hans-Willem Snoeck

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1/12/2017Use Of TBX1 Antibody From Abcam On Embryonic Tissue J ChalThis antibody was used to analyze the distribution of TBX1 in embryonic tissues. This polyclonal anti TBX1 antibody appears distributed in nuclei and is expressed moderately in some mesodermal tissues... Read Review

Anti-TBX1 antibody from Abcam

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Anti-TBX1 antibody from Abcam

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