Fig 2: ZC3H8 predicted structure and expression in tumors. a) Domain map of ZC3H8 shows a putative CK2 phosphorylation site at amino acid T32 and three putative C3H1 zinc finger motifs in the c-terminus. b) RT-qPCR survey of tumor cell lines derived from mouse mammary tissue expressing Zc3h8. Experiments were performed in triplicate, error bars represent standard deviation. c) Kaplan-Meier plot of disease-specific survival of breast cancer with high and low expression of ZC3H8, from Prognoscan data set GSE1456-GPL97, p value = 0.043377, hazard ratio 2.30, 95% CI = 0.85–6.24, Cox p value = 0.100218 [24, 25]