Anti-LOX antibody ab31238 from Abcam

Product Specs
ItemAnti-LOX antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab31238
ClonalityPolyclonal
Quantity100 UG
ApplicationsWestern blot
IsotypeIgG
HostRabbit
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NameLox
ReactivityHuman, Mouse
TargetLOX
Antibody TypePrimary

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Single-cell analysis reveals lysyl oxidase (Lox)(+) fibroblast subset involved in cardiac fibrosis of diabetic miceJournal of advanced researchDecember 1, 2023Li H, Zhu X, Cao X, Lu Y, Zhou J, Zhang X.the membranes were incubated with the following primary antibodies: β-actin (#A5316, Sigma), Lox (#ab31238, Abcam), p-Smad2 (#18338, Cell Signaling Technology), Smad2 (#5339, Cell Signaling Technology), p-Smad3

(2) Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated GenesInternational journal of molecular sciencesSeptember 26, 2022Liburkin-Dan T, Nir-Zvi I, Razon H, Kessler O, Neufeld G.antibodies (sc-166632) were from Santa Cruz, Biotechnology, Inc., Dallas, TX, USA. The rabbit anti-LOX (ab31238) and rabbit anti-LOXL4 (ab88186) were from Abcam (Cambridge, UK). The mouse anti-actin (clone AC-74,

(3) Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosisNature communicationsSeptember 22, 2022Chaudhari N, Findlay AD, Stevenson AW, Clemons TD, Yao Y, Joshi A, Sayyar S, Wallace G, Rea S, Toshniwal P, et al.stained using the Bond Dewax solution kit (Leica AR9222) with Rabbit anti-human LOX antibody (Abcam, AB31238) diluted 1:2000 with Bond Primary Antibody Diluent (Leica AR9352). Sections were then processed using

(4) Craniofacial tendon development—Characterization of extracellular matrix morphology and spatiotemporal protein distributionFrontiers in Cell and Developmental BiologySeptember 7, 2022Stefanie H. Korntner, Aniket Jana, Elizabeth Kinnard, Emily Leo, Timothy Beane, Xianmu Li, Rohit Sengupta, Lauren Becker, Catherine K. KuoDevelopmental Studies Hybridoma Bank (DSHB), Iowa, United States, 1:100), COL3 (3B2, DSHB, Iowa, United States, 1:100), LOX (ab31238, Abcam, 1:100), MMP2 (ab97779, Abcam, 1:100), and MMP9 (ab38898, Abcam, 1:100), or with normal horse

(5) Correlation of Matrisome-Associatted Gene Expressions with LOX Family Members in Astrocytomas Stratified by IDH Mutation StatusInternational Journal of Molecular SciencesAugust 23, 2022Talita de Sousa Laurentino, Roseli da Silva Soares, Suely Kazue Nagahashi Marie, Sueli Mieko Oba-ShinjoUSA). Specimens were then blocked and further incubated with primary antibodies against human LOX (ab31238, Abcam, Cambridge, UK), LOXL1 (HPA 042111, Sigma-Aldrich, St Louis, MO, USA), and LOXL3 (ARP60280, Aviva,

(6) Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic SclerosisInternational journal of molecular sciencesMay 16, 2022Yao Y, Findlay A, Stolp J, Rayner B, Ask K, Jarolimek W.release and stained by immunohistochemistry using primary antibodies against LOX (Abcam, Cambridge, UK, AB31238) or α-SMA (Abcam, Cambridge, UK, AB5694). 4.8. Analysis The fibrotic index in bleomycin lung slides

(7) Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signalingReproductive Medicine and BiologyJanuary 1, 2022Qingqing Huang, Xishi Liu, Sun‐Wei GuoWestern blot Alpha smooth muscle actin (α‐SMA),"Abcam, UK",ab5694,1:1000 Lysyl oxidase (LOX),Abcam,ab31238,1:1000 Cyclooxygenase‐2 (COX‐2),Abcam,ab15191,1:1000 E‐series of prostaglandin Receptors type 2 (EP2),Abcam,ab167171,1:2500 E‐series

(8) Human Lysyl Oxidase Over-Expression Enhances Baseline Cardiac Oxidative Stress but Does Not Aggravate ROS Generation or Infarct Size Following Myocardial Ischemia-ReperfusionAntioxidants (Basel)December 29, 2021Laura Valls-Lacalle, Lídia Puertas-Umbert, Saray Varona, José Martínez-González, Cristina Rodríguez, Antonio Rodríguez-Sinovasmin and blocked with 10% normal serum. Immunostaining was carried out with an antibody against LOX (ab31238, Abcam, Cambridge, UK). After extensive washing, a biotinylated goat anti-rabbit secondary antibody

(9) Lysyl oxidase engineered lipid nanovesicles for the treatment of triple negative breast cancerScientific ReportsDecember 1, 2021Alessandro De Vita et al.(Sigma-Aldrich) at room temperature and incubated overnight at 4 °C with anti-LOX antibody (1:1000 ab31238, Abcam, Cambridge, UK). The membranes were then washed and incubated for 1 h at room temperature with

(10) Analysis of Colorectal Carcinogenesis Paradigm between Cold Constitution and Heat Constitution: Earlier ECM Collagen DepositionEvidence-Based Complementary and Alternative MedicineJuly 17, 2021Feifei Nong, Yuqi Liang, Shangping Xing, Huixuan Li, Xizheng Lin, Jingchun Qin, Fengliang Hu, Bin Wen(dilution 1 : 500, Abcam, ab34710); COL III (dilution 1 : 100, Abcam, ab7778), LOX (dilution 1 : 50, Abcam, ab31238), and LOXL2 (dilution 1 : 500, Abcam, ab197779). All other chemicals and reagents used in immunohistochemical staining

(11) Î²-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblastsâ˜†Bone ReportsJune 1, 2021Eileen J. Daley, Philip C. Trackmananalyzed by Western blot with a β-catenin (Santa Cruz catalogue #7963) and LOX antibody (Abcam, catalogue #Ab31238) to examine their respective protein levels. 2.5 Statistical analysis All signaling experiments were

(12) Resistin induces cardiac fibroblast-myofibroblast differentiation through JAK/STAT3 and JNK/c-Jun signalingPharmacological researchMay 1, 2021Singh R, Kaundal RK, Zhao B, Bouchareb R, Lebeche D.#3270, c-Jun #9165, β actin # 12262, α-smooth muscle actin #19245, (Cell Signaling Technology), LOX #ab31238, CTGF #ab6992 (Abcam), resistin # 5997 (Biovision), Alexa Fluor 488-conjugated phalloidin (#A12379,

(13) A matricellular protein fibulin-4 is essential for the activation of lysyl oxidaseScience AdvancesNovember 27, 2020Kazuo Noda et al.anti-HA (Medical & Biological Laboratories Co., M192-3S and M180-3, respectively), anti-LOX (Abcam, ab31238), anti-ATP7A (Abcam, ab13995), and anti–Golgin-97 (Cell Signaling Technology, 13192) antibodies. Secondary

(14) Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in MiceCirculationNovember 17, 2020Michihiro Okuyama et al.nonaneurysmal and aneurysmal abdominal aortic sections (red indicates positive immunostaining; Abcam, ab31238; n=3, *P<0.05 AAA vs NAA; $P<0.05 female NAA vs male NAA; #P<0.05 female AAA vs male AAA; 2-way ANOVA

(15) Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in MiceJACC. Basic to translational scienceFebruary 1, 2020Hirakata S, Aoki H, Ohno-Urabe S, Nishihara M, Furusho A, Nishida N, Ito S, Hayashi M, Yasukawa H, Imaizumi T, et al.(no. 5339, Cell Signaling Technology), phospho-Smad2 (no. 3108, Cell Signaling Technology), Lox (no. ab31238, Abcam), cyclin D3 (no. 2936, Cell Signaling Technology), and phosphotyrosine (PY20, no. ab16389, Abcam). Tissue staining

(16) Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancerCancer ScienceDecember 1, 2019Rebecca Kalikawe et al.treatment for 30 minutes. The sections were then incubated with the rabbit anti‐LOX polyclonal Ab (ab31238) (Abcam) at a dilution of 1:100 at 4°C overnight. For negative controls, this primary Ab was replaced

(17) Thrombospondin-2 regulates extracellular matrix production, LOX levels, and cross-linking via downregulation of miR-29Matrix BiologySeptember 1, 2019N.E. Calabro, A. Barrett, A. Chamorro-Jorganes, S. Tam, N.J. Kristofik, Xing Xing, Ayomiposi M. Loye, W.C. Sessa, K. Hansen, T.R. Kyriakidessodium azide/MeOH) for 30 minutes and blocked in 1% BSA/PBS for 30 minutes. Primary LOX antibody (Abcam; Ab31238) was used at a 1:100 dilution and incubated at 4°C overnight. Secondary antibody, anti-rabbit HRP, was

(18) Lysyl oxidase induces epithelial‐mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinomaCancer ScienceApril 18, 2019Naoki Umezaki et al.of pH 9 and microwaving for 20 minutes. The sections were incubated with anti‐LOX antibody (1:100, Ab31238; Abcam, Cambridge, UK), anti‐TWIST antibody (1:50, sc‐15393; Santa Cruz Biotechnology, Dallas, TX, USA)

(19) Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contractureEuropean Journal of Medical ResearchDecember 1, 2018Patrina S. P. Poh et al.°C Alpha-smooth muscle actin Millipore (CBL171) 1:300 1 h at room temperature Lysyl Oxidase Abcam (ab31238) 1:200 Overnight at 4 °C mechanical testing was done within 24 h after sample collection. Since all

(20) Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activityScientific reportsSeptember 5, 2018Varona S, Orriols M, Galán M, Guadall A, Cañes L, Aguiló S, Sirvent M, Martínez-González J, Rodríguez C.to antigen retrieval (10 mM citrate pH 6.0) and blocked with 10% serum/PBS. Antibodies against LOX (ab31238, Abcam), LOX-PP (NB110-41568, Novus Biologicals) and MAC3 (sc-19991, Santa Cruz Biotechnology Inc.,

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Anti-LOX antibody from Abcam

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Anti-LOX antibody from Abcam

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