SGK1 (D27C11) Rabbit mAb 12103S from Cell Signaling Technology

Product Specs
ItemSGK1 (D27C11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12103S
Quantity100 µl
ApplicationsW, W-S, IP
ReactivityH
ClonalityMonoclonal
TargetSGK1
HostRabbit
NCBI Full Gene Nameserum/glucocorticoid regulated kinase 1
NCBI Gene AliasesSGK
Research AreaPI3K / Akt Signaling
IsotypeIgG
CloneD27C11
Molecular Weight45-60

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Palmitic acid aggravates atopic dermatitis by regulating SGK1/NEDD4L-involved cutaneous neuroimmune inflammation through driving TRPV1 and MRGPRB2 S-palmitoylationInflamm ResFebruary 2, 2026Bangtao Chen, Jing Yang, Tingting Song, Weiyu Wu, Fei Hao, Zhi Yang#AP0843, ABclonal), anti-GAPDH (#A19056, Abclonal), anti-β-Tubulin (#A12289, Abclonal), anti-SGK1 (#12103, CST), anti-phosphorylated SGK1 (Ser78, #5599, CST), anti-TRPV1(#AF8250, Beyotime), anti-Flag(#MA5-50638,

(2) High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanomaCell Death & DiseaseDecember 20, 2025Clivia Lisowski, Natascha E. Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, et al.(Sigma-Aldrich, #L7543), beta actin (Cell Signaling, #4970S), NFAT5 (Novus, #NB120-3446), SGK1 (Cell Signaling, #12103) and Mc1r (Invitrogen, #PA5-21911). Proteomics Ex vivo tumor cells were lysed and denatured with 2%

(3) Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct CellsFunction (Oxford, England)September 15, 2025Nickerson AJ, Albalawy WN, Youm EB, Joseph NA, Szekely KG, Kleyman TR, Weisz OA, Kashlan OB.blocking solution containing one of the following primary antibodies: rabbit anti-Sgk1 (Cell Signaling #12103; 1:1000), rabbit anti-ENaCγ (Stressmarq #SPC-405; 1:1000), or mouse anti-NaKα (Developmental Studies

(4) Gene-environment interaction modifies the association between hyperinsulinemia and serum urate levels through SLC22A12Journal of Clinical InvestigationMay 15, 2025Wataru Fujii, Osamu Yamazaki, Daigoro Hirohama, Ken Kaseda, Emiko Kuribayashi-Okuma, Motonori Tsuji, Makoto Hosoyamada, Yuta Kochi, Shigeru Shibata9271), AKT (Cell Signaling Technology, catalog 4691), and SGK1 (Cell Signaling Technology, catalog 12103). Urate transport. HEK cells expressing no hURAT1, hURAT1WT, or hURAT1T408A were seeded in 24-well

(5) Nedd4L signaling contributes to carbon tetrachloride-induced liver fibrosis in female mice and is associated with enteric dysbacteriosisGastroenterol Rep (Oxf)March 10, 2025Cheng Chen, Yanghui Bi, Bangtao Chen, Song HeCollagen I (#A21059) were obtained from ABclonal Technology Co., Ltd (Wuhan, Hubei, China). Anti-SGK1 (#12103) and phospho-SGK1 (Ser78; #5599) antibodies were purchased from Cell Signaling Technology (Shanghai,

(6) SGLT2 inhibition attenuates diabetic tubulopathy by suppressing SGK1-mediated pyroptosisFrontiers in endocrinologyJanuary 1, 2025Shi X, Zou W, Li X, Liu S, Hu T, Li Q, Zhang T, Chen L, Wu S, Wang C, et al.1:5000), phospho-SGK1 (Ser422) (Affinity Biosciences, AF3001, RRID: AB_2834440, 1:1000), SGK1 (CST, 12103S, RRID: AB_2687476, 1:2000), β-actin(HUABIO, HA722023, AB_3096833, 1:10,000), phospho-NF-κb(S536) (CST,

(7) MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristicsCell ReportsJanuary 1, 2025Sayali Joseph, Xingyuan Zhang, Gaith N. Droby, Di Wu, Victoria Bae-Jump, Scott Lyons, Angie Mordant, Allie Mills, Laura Herring, Blake Rushing, et al.,Cell signaling technology,Cat#12741; RRID:AB_2617131 Rabbit monoclonal anti-SGK1,Cell signaling technology,Cat#12103; RRID:AB_2687476 Rabbit monoclonal anti-phsopho-SGK1 (Ser78),Cell signaling technology,Cat#5599; RRID:AB_10698593 Rabbit

(8) NEXMIF overexpression is associated with autism-like behaviors and alterations in dendritic arborization and spine formation in miceFrontiers in neuroscienceJanuary 1, 2025Odamah K, Nishizawa Criales MT, Man HY.(1:1000 for WB, Synaptic Systems 256,003), rabbit-anti SGK1 (1:1000 for WB; Cell Signaling Technology #12103), rabbit-anti Cerebellin-1 (1:1000 for WB; Boster Bio A09176-1), rabbit anti-β-tubulin III (1:1000 for WB

(9) CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasiaNature Cardiovascular ResearchNovember 1, 2024Sajeth Dinakaran, Sima Qutaina, Haitian Zhao, Yuefeng Tang, Zhimin Wang, Santiago Ruiz, Aya Nomura-Kitabayashi, Christine N. Metz, Helen M. Arthur, Stryder M. Meadows, et al.Cell Signaling Technology, 4858), ID1 (1:1,000, BioCheck, BCH-1/195–14), SGK1 (1:1,000, Cell Signaling Technology, 12103), pSMAD1/5/8 (1:1,000, Cell Signaling Technology, 13820), SMAD1 (1:1,000, Cell Signaling Technology,

(10) AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanismsCell Chemical BiologyDecember 1, 2023Johnny Castillo Castillo Cabrera, Hong Dang, Adam Graves, Zhigang Zhang, Jose Torres-Castillo, Kelin Li, Zayna King, Pengda Liu, Jeff Aubé, James E. Bear, et al.,Cell Signaling Technologies,Cat# 2146S Lamin A/C,Cell Signaling Technologies,Cat# 4777 SGK1,Cell Signaling Technologies,Cat# 12103 SGK3,Cell Signaling Technologies,Cat# 8154 BiP,Cell Signaling Technologies,Cat# 3177T STAT1,Cell Signaling Technologies

(11) Sphingosine 1-phosphate receptor 2 promotes the onset and progression of non-alcoholic fatty liver disease-related hepatocellular carcinoma through the PI3K/AKT/mTOR pathwayDiscov OncolJanuary 11, 2023Wang G, Zhang X, Zhou Z, Song C, Jin W, Zhang H, Wu W, Yi Y, Cui H, Zhang P, et al.Beta-Actin antibody (CST, Item No. 3700S, USA), SGK1 (D27C11) Rabbit Monoclonal Antibody (CST, Item No. 12103S, USA), PI3 Kinase p85α (6G10) Mouse mAb (CST, Item No. 13666S, USA), PKCα (D7E6E) rabbit monoclonal

(12) Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancerProceedings of the National Academy of Sciences of the United States of AmericaOctober 25, 2022Tu Z, Hu Y, Raizada D, Bassal MA, Tenen DG, Karnoub AE.CST), INPP4B (#4039, CST), Skp2 (#2652, CST), hnRNPA2B1 (#9304, CST), PKCα (#2056, CST), and SGK1 (#12103, CST). Antibodies for phospho-PKCαSer657 (sc-377565) and phospho-SGK1Ser422 (sc-16745) were purchased

(13) Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infectionVirologyOctober 1, 2022Yuan LX, Yang B, Fung TS, Chen RA, Liu DX.100 U/ml penicillin, and 100 g/ml streptomycin. Antibodies against cFOS (#2250), cJUN (#9165), SGK1 (#12103), GADD45A (#4632), β-actin (#4967) were purchased from Cell Signaling Technology. RGS2 (10,678-1AP)

(14) Curcumin and Carnosic Acid Cooperate to Inhibit Proliferation and Alter Mitochondrial Function of Metastatic Prostate Cancer CellsAntioxidants (Basel, Switzerland)October 11, 2021Ossikbayeva S, Khanin M, Sharoni Y, Trachtenberg A, Tuleukhanov S, Sensenig R, Rom S, Danilenko M, Orynbayeva Z.were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Phospho-SGK1 (Ser78; #5599) and SGK1 (#12103) were obtained from Cell Signaling Technology (Danvers, MA, USA), and phospho-SGK (Ser422; #SAB4503834)

(15) Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinaseCell ReportsOctober 5, 2021Ben Zhou, Yuyao Zhang, Sainan Li, Lianfeng Wu, Geza Fejes-Toth, Aniko Naray-Fejes-Toth, Alexander A. Soukas(C4),Abcam,Cat# ab14128; RRID:AB_300931 Rabbit monoclonal anti-SGK1 (D27C11),Cell Signaling Technology,Cat# 12103; RRID:AB_2687476 Rabbit monoclonal anti-SGK2 (D7G1),Cell Signaling Technology,Cat# 7499; RRID:AB_10828732 Rabbit

(16) Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformationHGG AdvApril 8, 2021Ugwu N, Atzmony L, Ellis KT, Panse G, Jain D, Ko CJ, Nassiri N, Choate KA.rabbit anti-phospho-Akt-S473 (CST 4051), rabbit anti-serum/glucocorticoid-regulated kinase 1 (SGK1) (CST 12103) 1:1,000, rabbit anti-phospho-SGK1-Ser78 (CST 5599) 1:1,000, anti-phospho-SGK1-Thr256 (Thermo Fisher

(17) Acid sphingomyelinase promotes SGK1-dependent vascular calcificationClinical ScienceFebruary 12, 2021Trang Thi Doan Luong et al.were incubated overnight at 4◦ C with primary antibodies: rabbit anti-SGK1 antibody (diluted 1:1000, #12103) or rabbit anti-GAPDH antibody (diluted 1:5000, #2118) and then with secondary anti-rabbit HRP-conjugated

(18) Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic ConditionsInternational Journal of Molecular SciencesSeptember 29, 2020Florian Poetsch, Laura A. Henze, Misael Estepa, Barbara Moser, Burkert Pieske, Florian Lang, Kai-Uwe Eckardt, Ioana Alesutan, Jakob Voelklrabbit anti-RUNX2 (1:1000, #8486, Cell Signaling, Frankfurt am Main, Germany), rabbit anti-SGK1 (1:1000, #12103; Cell Signaling, Frankfurt am Main, Germany), rabbit anti-phospho-NDRG1 (Thr346 ) (1:1000, #3217; Cell Signaling

(19) Aldosterone-induced microRNAs act as feedback regulators of mineralocorticoid receptor signaling in kidney epithelia.The FASEB JournalSeptember 1, 2020Nejla Ozbaki‐Yagan, Xiaoning Liu, Andrew J. Bodnar, Jacqueline Ho, Michael Bruce ButterworthProduct 12G10 anti-alpha-tubulin). Anti-SGK1 Rabbit IgG (Cell Signaling Technology, Cat # D27C11, #12103, Davers, MA). Mice and Metabolic Experiments C57Bl/6 two month old male mice (obtained from Charles

(20) Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin DysregulationCancer cellApril 13, 2020Zhang Z, Zhou C, Li X, Barnes SD, Deng S, Hoover E, Chen CC, Lee YS, Zhang Y, Wang C, et al.)Glucocorticoid Receptor (D6H2L) XP® Rabbit mAb, Cell Signaling, Cat #12041(8)SGK1 (D27C11) Rabbit mAb, Cell Signaling, Cat #12103(9)c-Myc (D84C12) Rabbit mAb, Cell Signaling, Cat #5605 Immunofluorescence (IF) LNCaP/AR cells were

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SGK1 (D27C11) Rabbit mAb

SGK1 (D27C11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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SGK1 (D27C11) Rabbit mAb from Cell Signaling Technology

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