Anti-IKB alpha antibody [E130] ab32518 from Abcam

Product Specs
ItemAnti-IKB alpha antibody [E130]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab32518
Antibody TypePrimary
CloneE130
IsotypeIgG
Quantity10 UL, 40 UL, 100 UL
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
HostRabbit
Conjugate/TagUnconjugated
Gene NameNFKBIA
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
TargetIKB alpha

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) The linear ANRIL transcript P14AS regulates the NF-κB signaling to promote colon cancer progressionMol MedDecember 1, 2023Wanru Ma, Junhua Huab61193, UK), CDCP1 (Abcam, ab252947), ADAM10 (Abcam, ab124695), UBE2D3 (Abcam, ab176568), IκBa (Abcam, ab32518), Ago2 (Abcam, ab186733), YY1 (Santa Cruz, sc-7341, TX, USA), HNF3a (Santa Cruz, sc-514,695), GAPDH

(2) Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 AxisAntioxidants (Basel)October 29, 2023Weixi Xie, Lang Deng, Miao Lin, Xiaoting Huang, Rui Qian, Dayan Xiong, Wei Liu, Siyuan TangCST, Danvers, MA, USA), Pho-p65 antibody (1:1000, Cat# 3033T, CST, USA), IκB α antibody (1:1000, Cat# ab32518, Abcam, UK), Pho-IκB α antibody (1:10,000, Cat# ab133462, Abcam, UK), Pho-JNK antibody (1:1000, Cat#

(3) RTKN2 Inhibits the Growth, Migration, Invasion and Glycolysis of Lung Adenocarcinoma Cells by Inactivating the NF-κB Signalling PathwayBiochemical GeneticsOctober 1, 2023Na Wang, Jinxiang Wangab8805; anti-p-AKT, ab38449; anti-p38, ab170099; anti-p-p38, ab211061; anti-β-catenin, ab32572; anti-IκB, ab32518; anti-p-IκB, ab133462; anti-GAPDH, ab8245; anti-H3, ab1791) at 4 °C overnight, followed by incubation

(4) Cinnamaldehyde Induces the Expression of MicroRNA-1285-5p and MicroRNA-140-5p in Chondrocytes to Ameliorate the Apoptosis and Inflammatory ResponseCARTILAGESeptember 1, 2023Gang Li, Yun SongInc.), anti-phospho-IKBα (p-IKBα) antibody (1:1,000, ab133462; Abcam Inc.), anti-IKBα antibody (1:1,000, ab32518; Abcam Inc.), anti-IKKα/β antibody (1:1,000, ab178870; Abcam Inc.), and anti-phospho-IKKα/β antibody

(5) Gαq-PKD/PKCμ signal regulating the nuclear export of HDAC5 to induce the IκB expression and limit the NF-κB-mediated inflammatory response essential for early pregnancyeLifeJuly 27, 2023Yufei Jiang, Yan He, Songting Liu, Gaizhen Li, Dunjin Chen, Wenbo Deng, Ping Li, Ying Zhang, Jinxiang Wu, Jianing Li, et al.ab76315, 1:1000), STAT3 (Abcam Cat# ab68153, 1:1000), rabbit polyclonal antibody against IκBa (Abcam Cat# ab32518, 1:1000), rabbit polyclonal antibody against p-NFκB p65(Ser536) (Bioss, Cat# bs-0982R, 1:1000), mouse

(6) TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitinationCell biology and toxicologyJune 1, 2023Zhu C, Chen W, Cui H, Huang Z, Ding R, Li N, Wang Q, Wu F, Zhao Y, Cong X.ab232401), ASC (Abcam; ab155970), caspase-1 (Abcam; ab207802), GSDMD-N (Abcam; ab215203), anti-IκBα (Abcam; ab32518), H3 (Cell Signaling Technology; 4499), and GAPDH (Cell Signaling Technology; 5174) followed by the

(7) Brucella abortus modulates macrophage polarization and inflammatory response by targeting glutaminases through the NF-κB signaling pathwayFrontiers in ImmunologyMay 31, 2023Tianyi Zhao, Zedan Zhang, Yitao Li, Zhihua Sun, Liangbo Liu, Xingmei Deng, Jia Guo, Dexin Zhu, Shuzhu Cao, Yingjin Chai, et al.anti-p-NF-κB (ab76302, 1:1000), anti-NF-κB (ab32536, 1:1000), anti-p-IKBα (ab133462, 1:1000), anti-IKBα (ab32518, 1:1000), anti-GLS (156876, 1:1000). The membrane was incubated with horseradish peroxidase-conjugated

(8) 5-ALA/SFC Ameliorates Endotoxin-Induced Ocular Inflammation in Rats by Inhibiting the NF-κB Signaling Pathway and Activating the HO-1/Nrf2 Signaling PathwayInternational journal of molecular sciencesMay 12, 2023Otaka Y, Kanai K, Mori A, Okada D, Nagai N, Yamashita Y, Ichikawa Y, Tajima K.Antibodies and Reagents Antibodies against iNOS (ab3523), Cox-2 (ab179800), HO-1 (ab13243), and IκB-α (ab32518) were purchased from Abcam (Cambridge, UK). NF-κB p65 (sc-372) was purchased from Santa Cruz Biotechnology

(9) Alkannin reverses lipopolysaccharides-induced inflammatory responses by suppressing mitogen-activated protein kinase and nuclear factor kappa-B signallingBioengineeredApril 27, 2023Jingya Yang, Jing Li, Lanzhu Yang, Ruohui Guoanti-p-p65 (ab76302, Abcam), anti-p65 (ab16502, Abcam), anti-p-IκB-α (ab133462, Abcam), anti-IκB-α (ab32518, Abcam), and anti- glyceraldehyde-3-phosphate dehydrogenase (GADPH; ab8245, Abcam). Ethical approval

(10) Biomimetic Remodeling of Microglial Riboflavin Metabolism Ameliorates Cognitive Impairment by Modulating NeuroinflammationAdvanced science (Weinheim, Baden-Wurttemberg, Germany)April 1, 2023Zhang M, Chen H, Zhang W, Liu Y, Ding L, Gong J, Ma R, Zheng S, Zhang Y.the Proteintech Group (Rosemont, IL, USA). Anti‐Phospho‐IκBα (ab133462), Iba1 (ab178847), and IκBα (ab32518) antibodies were purchased from Abcam (Cambridge, MA, USA). Anti‐GFAP (MAB360) and NeuN (MAB377) antibodies

(11) Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4 /NF-κB pathwayEuropean Journal of HistochemistryMarch 20, 2023Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xup-NF-κB p65 (1:1000, ab76302), NF-κB p65 (1:500, ab19870), p-IκB-α (1:10000, ab133462), IκB-α (1:1000, ab32518), or β-actin (1:500, ab8226) overnight at 4°C. Subsequently, membranes were incubated with goat anti-rabbit

(12) CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathwayInternational Journal of Biological SciencesFebruary 27, 2023Tsung-Ming Chang, Yao-Chang Chiang, Chiang-Wen Lee, Chieh-Mo Lin, Mei-Ling Fang, Miao-Ching Chi, Ju-Fang Liu, Yu Ru Koup65 (#8242), and ZO-1 (#8193) were purchased from Cell Signaling Technology (Danvers, MA, USA). IκBα (ab32518) was purchased from Abcam (Cambridge, UK), and CXCL14 (GTX108431), ACKR2 (GTX21658), C-X-C motif chemokine

(13) Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky GutCellsFebruary 24, 2023d'Angelo M, Brandolini L, Catanesi M, Castelli V, Giorgio C, Alfonsetti M, Tomassetti M, Zippoli M, Benedetti E, Cesta MC, et al.following primary antibodies diluted in EBB: anti-NFκB (1:1000, ab32536, Abcam, UK), anti-IKBα (1:1000, ab32518, Abcam, UK), anti-pIKK (1:500, 2697, Cell Signaling, Danvers, MA, USA), anti-PPARγ (1:1000, ab178860,

(14) Effects of Fish Oil, Lipid Mediators, Derived from Docosahexaenoic Acid, and Their Co-Treatment against Lipid Metabolism Dysfunction and Inflammation in HFD Mice and HepG2 CellsNutrientsJanuary 13, 2023Yan Su, Hack-Sun Choi, Jong-Hyun Choi, Hee-Sik Kim, Gil-Yong Lee, Hee-Won Cho, Heonsik Choi, Yong-Suk Jang, Jeong-Woo Seofrom Sango Company (San Diego, CA, USA). Antibodies against IKKB (ab32135), p-IKKB (ab194528), IKB (ab32518), p-IKB (ab133462), NF-kB (p65) (ab16502), p-NF-kB (p-p65) (ab76302), and GAPDH (ab181602) were purchased

(15) FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF PathwaysJournal of Immunology ResearchJanuary 6, 2023Chongwei Chen, Sujing Zong, Zhenyu Wang, Ruijia Yang, Yanjing Guo, Yunfei Wang, Xinping Chen, Yue Li, Shaowei Wanganti-MEF2C (Abcam, rabbit, IgG, EPR19089-202, ab211493, 0.57 μg/mL), anti-IκBa (Abcam, rabbit, IgG, E130, ab32518, 0.091 μg/mL), anti-NF-κB p65 (Affinity, mouse, IgG1, BF0382, 1 μg/mL), p-NF-κB p65 (Affinity, rabbit,

(16) Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's DiseaseResearch (Washington, D.C.)January 1, 2023Huang Q, Jiang C, Xia X, Wang Y, Yan C, Wang X, Lei T, Yang X, Yang W, Cheng G, et al.Biochem Ltd. (Shanghai, China). Anti-beta amyloid antibody (ab201060) and anti-IKB alpha antibody (ab32518) were purchased from Abcam (UK). NF-κB p65 antibody was obtained from Cell Signaling Technology, Inc.

(17) Muse cells decrease the neuroinflammatory response by modulating the proportion of M1 and M2 microglia in vitroNeural regeneration researchJanuary 1, 2023Yin XY, Wang CC, Du P, Wang XS, Lu YC, Sun YW, Sun YH, Hu YM, Chen X.(phospho S536) (1:1000, Abcam, Cat# ab86299, RRID: AB_1925243), rabbit anti-IκBα (1:1000, Abcam, Cat# ab32518, RRID: AB_733068), rabbit anti-IκBα (phospho S32) (1:1000, Cell Signaling Technology, Danvers, MA, USA,

(18) β-Hydroxy-β-Methylbutyric Acid Promotes Repair of Sheep Myoblast Injury by Inhibiting IL-17/NF-κB SignalingInternational Journal of Molecular SciencesDecember 27, 2022Juan Zheng, Bo Li, Yiting Yan, Xiaoyu Huang, Enping Zhang1:1000; Cell Signaling Technology, Beverly, MA, USA), IKKα (ab32041, 1:1000; Abcam, Cambridge, UK), IKBα (ab32518, 1:1000; Abcam, Cambridge, UK) and GAPDH (ProProtection, 1:5000; Abcam, Cambridge, UK)) at 4 °C overnight,

(19) Mechanisms and Effects of Isorhamnetin on Imiquimod-Induced Psoriasiform Dermatitis in MiceLife (Basel)December 15, 2022Chieh-Shan Wu, Chuan-Chao Lin, Yu-Ying Chen, Deng-Ho YangThen, the membrane was probed with primary antibodies rabbit monoclonal anti-IκB-α (1:1000 dilution; ab32518) (Abcam, Cambridge, UK) and rabbit polyclonal anti-NF-κB p65 (1:1200 dilution; ab16502) (Abcam, Cambridge,

(20) Oenanthe javanica Ethanolic Extract Alleviates Inflammation and Modifies Gut Microbiota in Mice with DSS-Induced ColitisAntioxidants (Basel)December 9, 2022Ui-Jin Bae, Ha-Na Jang, Sung-Hyen Lee, Ji-Young Kim, Gi-Chang KimUSA) for 1 h. Antibodies against iNOS (ab3523), COX-2 (ab15191), IL-1β (ab9722), TNF-α (ab9739), IκBα (ab32518), p-IκBα (ab133462), p-p65 (ab86299), Lamin B1 (ab16048), NQO1 (ab34173), HO-1 (ab13248), Nrf2 (ab92946)

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Anti-IKB alpha antibody [E130] from Abcam

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Anti-IKB alpha antibody [E130] from Abcam

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