PE/Cyanine7 anti-mouse CD49b (pan-NK cells) 108921 from BioLegend

Product Specs
ItemPE/Cyanine7 anti-mouse CD49b (pan-NK cells)
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number108921
Quantity25 µg
ApplicationsFlow Cytometry (FC)
Conjugate/TagPE_CYANINE7
ReactivityMouse
IsotypeIgM, Kappa
CloneDX5
HostRat
NCBI Full Gene Nameintegrin alpha 2
NCBI Gene AliasesCD49B, DX5, GPIa
Concentration0.20 mg/mL
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
ImmunogenIL-2-propagated NK1.1⁺ cells from C57BL/6 mice
Antibody TypePrimary
ClonalityMonoclonal
TargetCD49b

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Company Profile

Website: biolegend.com

(1) Combined angiogenesis and PD-1 inhibition for immunomodulatory TNBC: concept exploration and biomarker analysis in the FUTURE-C-Plus trialMolecular CancerDecember 1, 2022Song-Yang Wu et al.(Biolegend, Cat#100328), CD4 (Biolegend, Cat#100536), CD8a (BioLegend, Cat#100708), and CD49b (BioLegend, Cat#108922). For intracellular proteins, cells were fixed and permeabilized with fixation buffer (BioLegend, Cat#420801)

(2) Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protectionCell reportsOctober 18, 2022VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry JA, Gebara E, Cross AR, Cheung LS, Dykema AG, et al.[RM4-5],ThermoFisher Scientific,Cat# 48-0042-82; RRID: AB_1272194 Anti-mouse CD49b PE-Cy7 [DX5],BioLegend,Cat# 108922; RRID: AB_2561460 Anti-mouse CD16/32 [2.4G2],BD Biosciences,Cat# 553142; RRID: AB_394657 Anti-mouse

(3) HLA-II Alleles Influence Physical and Behavioral Responses to a Whey Allergen in a Transgenic Mouse Model of Cow's Milk AllergyFrontiers in AllergyApril 14, 2022Danielle L. Germundson, Suba Nookala, Nicholas A. Smith, Yassmine Warda, Kumi Nagamoto-Combs,Tonbo Biosciences,75-0032-U100 CD4,BV605,1.25/100,RM4-5,BioLegend,100548 CD8,APC,1.25/100,53-6.7,BioLegend,100712 CD11b,APC,1.25/100,M1/70,BioLegend,101212 CD11c,BV711,0.25/100,N418,BioLegend,117349 CD14,BV605,1.25/100,RA3-6B2,BioLegend,123335 CD19,BV785,5/100,6D5,BioLegend,115543 CD25,PE,1/100,PC61,BioLegend,102008 CD45,PerCPCy5-5,1.25/100,30-F11,BioLegend,103132 CD49b,PE-Cy7,2.5/100,DX5,BioLegend,108921 CD80,PECY7,2.5/100,16-10A1,BioLegend,104733 CD86,FITC,2/100,GL-1,BioLegend,105005 CD206,PE,2.5/100,C068C2,BioLegend,141705 F4/80,BV785,2.5/100,BM8,BioLegend,123141 HLA-DR,FITC,1/20,L243,BioLegend,307604 HLA-DQ,FITC,1/20,HLADQ1,BioLegend,318104 IgM,APC,5/100,RMM-1,BioLegend,406509 Ly6G,PE-Cy7,1.25/100,1A8,BioLegend,127617 Ly6C,BV421,1/20,HK1.4,BioLegend,128031 TCRβ,FITC,2/100,H57-597,BioLegend,109205 Antibodies

(4) Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune ResponsesCancer immunology researchApril 1, 2022Fedoriw A, Shi L, O'Brien S, Smitheman KN, Wang Y, Hou J, Sherk C, Rajapurkar S, Laraio J, Williams LJ, et al.anti-CD19 (TONBO biosciences, 35–0193-U500; BioLegend, San Diego, CA; 115543), anti-CD49B (BioLegend, 108922), anti-NK1.1 (BD Biosciences, 550627), anti-CD11b (eBioscience, 48–0112-82; BD Biosciences, 561098),

(5) JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell inductionCell reportsFebruary 22, 2022Vogel A, Martin K, Soukup K, Halfmann A, Kerndl M, Brunner JS, Hofmann M, Oberbichler L, Korosec A, Kuttke M, et al.

(6) Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulationImmunityJune 8, 2021McFarland AP, Yalin A, Wang SY, Cortez VS, Landsberger T, Sudan R, Peng V, Miller HL, Ricci B, David E, et al.AB_395724 KLRG1 (PE),BioLegend,Cat: 138408; Clone: 2F1/KLRG1; RRID: AB_10574313 CD49b (PE-Cy7),BioLegend,Cat: 108922; Clone: DX5; RRID: AB_2561460 Ly6C (APC-Cy7),BioLegend,Cat: 128025; Clone: HK1.4; RRID: AB_10643867 CD49a

(7) Natural killer cells associate with amyotrophic lateral sclersois in a sex- and age-dependent mannerJCI InsightJune 8, 2021Benjamin J. Murdock, Joshua P. Famie, Caroline E. Piecuch, Kristen D. Raue, Faye E. Mendelson, Cole H. Pieroni, Sebastian D. Iniguez, Lili Zhao, Stephen A. Goutman, Eva L. Feldman(catalog 100326), PerCP-5.5-CD19 (catalog 115532), APC-CD45 (catalog 103112), PE/Cy7-CD49b (catalog 108921), PE/Cy7-Ly6G (catalog 127617), APC/Cy7-CD4 (catalog 100414), and APC/Cy7-CD11b (catalog 101226) (BioLegend).

(8) Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantationCell reportsMay 18, 2021Prosser A, Huang WH, Liu L, Dart S, Watson M, de Boer B, Kendrew P, Lucas A, Larma-Cornwall I, Gaudieri S, et al.

(9) Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine LiverCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Baier FA, Sánchez-Taltavull D, Yarahmadov T, Castellà CG, Jebbawi F, Keogh A, Tombolini R, Odriozola A, Dias MC, Deutsch U, et al.CA)",61-4875-82 APC,Roryt,AFKJS-9,eBioscience,17-6988-80 APC-efluor780,PD-1,J43,eBioscience,47-9985-82 eFluor450,PD-1,J43,eBioscience,48-9985-82 PE,IL-22,Poly5164,BioLegend,516404 Percp-efluor710,IL-22,1H8PWSR,eBioscience,46-7221-80 PE-cy7,CD49b,DX5,BioLegend,108922 PE-cy7,CD4,GK1.5,eBioscience,25-0041-81 APC,CD4,RM4-4,BioLegend,116014 BV570,CD8,53-6.7,BioLegend,301038 Alexa

(10) A Phase I, Dose Escalation, Single Dose Trial of Oral Attenuated Salmonella typhimurium Containing Human IL-2 in Patients With Metastatic Gastrointestinal CancersJournal of immunotherapy (Hagerstown, Md. : 1997)September 1, 2020Gniadek TJ, Augustin L, Schottel J, Leonard A, Saltzman D, Greeno E, Batist G.purchased from BioLegend (San Diego, CA): αCD8/FITC (100705), αCD4/PerCP-Cy5.5 (100539), αCD49b/PE/Cy7 (108921), αCD45.2/BV510 (109837), αCD11b/BV650 (101239) and BD Pharmingen: αLy6C/PerCP/Cy5.5 (560525) and αLy6G/AF700

(11) Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progressionCell researchOctober 1, 2019Wang X, Sun G, Feng T, Zhang J, Huang X, Wang T, Xie Z, Chu X, Yang J, Wang H, et al.Biolegend), B220(RA3-6B2)-BV421 (103240, Biolegend), CD19(6D5)-PE (115508, Biolegend), CD49b(DX5)-PE-Cy7 (108922, Biolegend), CD4(GK1.5)-PE-Cy7 (100422, Biolegend), CD4(GK1.5)-FITC (100406, Biolegend), CXCR3(CXCR3-173)-BV421

(12) IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α⁺ Dendritic Cells Promotes Listeria monocytogenes InfectionImmunityJuly 16, 2019Liu D, Yin X, Olyha SJ, Nascimento MSL, Chen P, White T, Gowthaman U, Zhang T, Gertie JA, Zhang B, et al.(H57–597),BioLegend,"Cat# 109222, RRID:AB_893625" PE/Cy7 anti-mouse CD49b (pan-NK cells) Antibody (DX5),BioLegend,"Cat# 108922, RRID:AB_2561460" PE anti-mouse/human CD11b Antibody (M1/70),BioLegend,"Cat# 101208, RRID:AB_312791" APC

(13) Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cellsScientific reportsApril 16, 2019Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, Kim J, Powers J, Gracia-Hernandez M, Oliveira V, et al.anti-mouse CD8a (CD8+ T cells) (Biolegend, 100766), APC/Fire 750 anti-mouse CD49b (NK cells) (Biolegend, 108922), Brilliant Violet 421 anti-mouse CD25 (T-cell activation) (Biolegend, 102034) and Brilliant Violet

(14) Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to TissuesImmunityDecember 18, 2018He W, Holtkamp S, Hergenhan SM, Kraus K, de Juan A, Weber J, Bradfield P, Grenier JMP, Pelletier J, Druzd D, et al.HMβ1-1",Biolegend,"Cat# 102218, RRID: AB_493711" "Anti-mouse CD49b, PE/Cy7, clone DX5",Biolegend,"Cat# 108922, RRID: AB_2561460" "Anti-mouse CD49d, PerCP/Cy5.5, clone R1-2",Biolegend,"Cat# 103620, RRID: AB_2563702" "Anti-mouse

(15) Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor SpheroidsCancer discoveryFebruary 1, 2018Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, et al.AF488 (BioLegend 103122), CD25 PE (BioLegend 101904), CD19 PE-Dazzle (115554), CD49b PE-Cy7 (BioLegend, 108922), CD3 BV421 (BioLegend, 100228), CD8 BV510 (BioLegend 100752), CD4 BV786 (Fisher Scientific # BDB563331);

(16) Bone marrow basophils provide survival signals to immature B cells in vitro but are dispensable in vivoPloS oneJanuary 1, 2017Moreau JM, Cen S, Berger A, Furlonger C, Paige CJ.

(17) Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus PersistencePLoS pathogensDecember 1, 2016Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, et al.

(18) Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 AntibodyJournal of immunology (Baltimore, Md. : 1950)November 15, 2015Victorino F, Sojka DK, Brodsky KS, McNamee EN, Masterson JC, Homann D, Yokoyama WM, Eltzschig HK, Clambey ET.

(19) Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancerOncotargetOctober 20, 2015Patel MR, Jacobson BA, Ji Y, Drees J, Tang S, Xiong K, Wang H, Prigge JE, Dash AS, Kratzke AK, et al.conjugates were purchased from BioLegend: αCD8/FITC (100705), αCD4/PerCP-Cy5.5 (100539), αCD49b/PE/Cy7 (108921), αCD45.2/PE (109808), αCD11b/BV650 (101239), αPDL1/PE-Cy7 (124313), αPDL1/ PE-Cy7 isotype (400617),

(20) Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer modelAnticancer researchFebruary 1, 2015Drees J, Mertensotto M, Liu G, Panyam J, Leonard A, Augustin L, Schottel J, Saltzman D.

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6/28/2018Anti-Mouse CD49b Antibody Matthew RatsepThis antibody is used extensively in flow cytometry panels to identify NK cells. The antibody gives a bright, robust signal. When gating on conventional NK cells (CD3-NKp46+) this antibody will ... Read Review

PE/Cyanine7 anti-mouse CD49b (pan-NK cells) from BioLegend

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PE/Cyanine7 anti-mouse CD49b (pan-NK cells) from BioLegend

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