Fig 1: (A) Gene expression of arginine vasopressin receptor 1A (AVPR1A) mRNA in the groups of women with first-episode psychosis during pregnancy (FE-PW) and healthy controls (HC-PW). (B) IRS scores for AVPR1A expression in the FE-PW group and the HC-PW group’s placental villi. (C) IRS scores for AVPR1A expression in the FE-PW group and the HC-PW group’s decidual cells. (D,E) Photographs demonstrating AVPR1A immunostaining in the placental villi and decidual cells of the FE-PW group, respectively. (F,G) Photographs demonstrating AVPR1A immunostaining in the placental villi and decidual cells of the HC-PW group, respectively. p < 0.01 (**); p < 0.001 (***). Blue arrows show increased tissue expression of AVPR1A in the different parts of the placental villi and decidual cells in FE-PW (D,E), whereas AVPR1A expression is almost limited to the syncytiotrophoblast layer in the placental villi of HC-PW (F).