Anti-AKT (phospho T308) antibody ab38449 from Abcam

Product Specs
ItemAnti-AKT (phospho T308) antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab38449
Antibody TypePrimary
Quantity100 UG
ClonalityPolyclonal
HostRabbit
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
IsotypeIgG
Conjugate/TagUnconjugated
Concentration1 mg/ml
ModificationsPhospho-T308
Gene NameAKT1
ReactivityHuman, Mouse, Rat
Targetpan-AKT

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathwayCancer Biology & TherapyDecember 31, 2023Yongjun Liu, Hua Yangtransfer on PVDF membrane was done following 12% SDS-PAGE separation. Primary antibodies against p-AKT (ab38449, Abcam), AKT (ab8805, Abcam), P-PI3K (ab278545, Abcam), PI3K (ab32089, Abcam, UK), HER2 (ab134182, Abcam),

(2) Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathwayPharmaceutical BiologyDecember 31, 2023Cuixia Liang, Yongjie Jiang, Lizhu Sunab182651), anti-Total-PI3K (1:1000; ab133595), anti-p-AKT (S473) (1:500; ab8932), anti-p-AKT (T308) (1:500; ab38449), anti-Total-AKT (1:500; ab300473) and anti-β-actin (1:5000; ab8227) antibodies (Abcam, Cambridge, UK).

(3) LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathwayEpigeneticsDecember 31, 2023Fei Qi, Zhong-Dong Lv, Wen-Di Huang, Shan-Chen Wei, Xin-Min Liu, Wei-Dong Song(ab45688, 1:1000, Abcam), p-PI3K (ab182651, 1:1000, Abcam), PI3K (ab191606, 1:1000, Abcam), p-Akt (ab38449, 1:500, Abcam), Akt (ab38449, 1:500, Abcam), p-mTOR (AP0094, 1:500, ABclonal), mTOR (A2445, 1:500, ABclonal),

(4) LINC00969 inhibits proliferation with metastasis of breast cancer by regulating phosphorylation of PI3K/AKT and ILP2 expression through HOXD8PeerJDecember 18, 2023Xiaoyun Wen, Ya Hou, Liang Zhou, Xiansong Fangapoptosis-like protein-2 (ILP2; ab9664, 1:1000), phosphoinositide 3-kinase (PI3K; ab191606, 1:1500), p-AKT (ab38449, 1:800), t-AKT (total AKT; ab8805, 1:2000), or GAPDH (ab9485, 1:3000). After rinsing, the membranes

(5) Sub-anaesthetic dose of propofol attenuates mechanical allodynia in chronic post-ischaemic pain via regulation of PTEN/PI3K/IL-6 signallingMolecular PainDecember 1, 2023Siu Yi Doreen Leung, Fei Meng, Jingjing Liu, Aijia Jessica Liu, Hei Lui Lhotse Ng, Chi Wai Cheung, Sau Ching Stanley Sau Ching Wonganti-phosphoPTEN (Abcam #ab195056, 1:150), anti-phospho-PI3Kp85α (Abcam #ab182651, 1:400), anti-phosphoAKT(Abcam #ab38449, 1:200), anti-GFAP (Sigma-Aldrich #MAB360, 1:500), anti-iba1(Santa cruz #sc-32725,1:500) and anti-NeuN

(6) Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF‐1 pathwayImmunity, Inflammation and DiseaseNovember 22, 2023Xinxin Yue, Wei Hao, Min Wang, Yang FuAbcam), IGF‐1 (ab134140, 22 kDa, 1:20,000; Abcam), IGF‐1R (ab182408, 156 kDa, 1:1000; Abcam), p‐AKT (ab38449, 56 kDa, 1:1000; Abcam), AKT (ab18785, 56 kDa, 2 µg/mL; Abcam), and glyceraldehyde 3‐phosphate dehydrogenase

(7) Exploring the targets and molecular mechanism of glycyrrhetinic acid against diabetic nephropathy based on network pharmacology and molecular dockingWorld Journal of DiabetesNovember 15, 2023Fan-Di Meng, Ling Yuan, Duo-Jie Xu, Meng-Ying Che, Shao-Zhang Hou, Dou-Dou Lu, Wen-Jing Liu, Yi Nanrabbit antibody,Abcam,ab278545 AKT rabbit antibody,Abcam,ab283852 Rabbit antibody to p-AKT,Abcam,ab38449 INSR Rabbit antibody,Wuhan Sanying,20433-1-AP Rabbit antibody to GSK3,Wuhan Sanying,13419-1-AP Rabbit

(8) Long non‑coding RNA PEG13 regulates endothelial cell senescence through the microRNA‑195/IRS1 axisExperimental and Therapeutic MedicineNovember 3, 2023Qin Huang, Haiwen Zhou, Songping Yu(p)-PI3K (1:500; cat. no. ab182651; Abcam), AKT (1:500; cat. no. ab8805, Abcam), p-AKT (1:500; cat. no. ab38449; Abcam), MDM2 (1:1,000; cat. no. ab259265; Abcam), p53 (1:2,000; cat. no. ab32049; Abcam), p21 (1:3,000;

(9) Phosphorylated S6K1 and 4E-BP1 play different roles in constitutively active Rheb-mediated retinal ganglion cell survival and axon regeneration after optic nerve injuryNeural Regeneration ResearchNovember 1, 2023Jikuan Jiang, Lusi Zhang, Jingling Zou, Jingyuan Liu, Jia Yang, Qian Jiang, Peiyun Duan, Bing Jiangrabbit, 1:150, Abcam, Cat# ab236632; RRID: AB_2864361), phospho-AKT-T308 (rabbit, 1:200, Abcam, Cat# ab38449; RRID: AB_722678), phospho-S6 (p-S6)-Ser240/244 (rabbit, 1:200, Cell Signaling Technology, Danvers,

(10) PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathwayAging (Albany NY)October 27, 2023Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu(10519-1-AP, Proteintech, dilution 1:100), AKT (Ab8805, Abcam, Cambridge, UK, dilution 1:500), P-AKT (Thr 308, Ab38449, Abcam, dilution 1:500), GSK-3β (AF5016, Affinity, USA, dilution 1:500), P-GSK-3β (Ser 9, AF2016, Affinity,

(11) Effects of Cinnamon Powder on Glucose Metabolism in Diabetic Mice and the Molecular MechanismsFoodsOctober 20, 2023Yaoyao Liu, Fan Liu, Dongxu Xing, Weifei Wang, Qiong Yang, Sentai Liao, Erna Li, Daorui Pang, Yuxiao Zou(GSK3β, cat. no. ab32391), glycogen synthase (GS, cat. no. ab40810), phosphorylated-AKT (p-AKT, cat. no. ab38449), and silent information regulator factor 2-related enzyme 1 (SIRT1, cat. no. ab189494) were supplied

(12) Activation of MG53 Enhances Cell Survival and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Injured HeartsStem Cell Reviews and ReportsOctober 1, 2023Ki Ho Park, Xingyu He, Lin Jiang, Hua Zhu, Jialiang Liang, Yigang Wang, Jianjie Ma3-phospate dehydrogenase (GAPDH; Santa Cruz, sc-32233), and anti-AKT (phospho T308) antibody (Abcam, ab38449). Different amounts of rhMG53 protein were loaded as positive controls. Immunoblots were visualized

(13) Fibronectin promotes tumor progression through integrin αvβ3/PI3K/AKT/SOX2 signaling in non-small cell lung cancerHeliyonSeptember 14, 2023Jin-Long Wu, Cheng-Feng Xu, Xu-Hui Yang, Ming-Song Wangrabbit monoclonal total-PI3K (1:500, ab302958, Abcam, Cambridge, UK), rabbit polyclonal p-AKT (1:500, ab38449, Abcam, Cambridge, UK), rabbit polyclonal total-AKT (1:500, Abcam, ab8805, Cambridge, UK) and mouse

(14) miR-181b promotes angiogenesis and neurological function recovery after ischemic strokeNeural regeneration researchSeptember 1, 2023Xue LX, Shu LY, Wang HM, Lu KL, Huang LG, Xiang JY, Geng Z, Zhao YW, Chen H.60203-2-Ig, RRID: AB_10912803), rabbit anti-phosphorylated-(T308)-Akt antibody (1:1000, Abcam, Cat# ab38449, RRID: AB_722678), mouse anti-VEGF antibody (1:1000, Proteintech, Cat# 66828-1-Ig, RRID: AB_2882171),

(15) Salvigenin Suppresses Hepatocellular Carcinoma Glycolysis and Chemoresistance Through Inactivating the PI3K/AKT/GSK-3β PathwayApplied Biochemistry and BiotechnologyAugust 1, 2023Hui Shao, Jingyan Chen, Ali Li, Lili Ma, Yongzhi Tang, Huazhong Chen, Yongping Chen, Junyan Liu1:1000), Anti-p-PI3K (PA5-104853, Thermo Fisher,1:1000), Anti-AKT (ab235958, Abcam, 1:1000), Anti-p-AKT (ab38449, Abcam, 1:1000), Anti-GSK-3β (ab32391, Abcam, 1:1000), Anti-p-GSK-3β (ab75814, Abcam, 1:1000), Anti-HK2

(16) FNBP1 Facilitates Cervical Cancer Cell Survival by the Constitutive Activation of FAK/PI3K/AKT/mTOR SignalingCellsJuly 29, 2023Jun Zhang, Xin Li, Yunfei Zhou, Mingming Lin, Qianying Zhang, Yunhong Wangab81298, EP2160Y), PI3K/p85 (phospho Tyr 607, ab182651; ab191606, EPR18702), AKT (phospho Tyr 308, ab38449; ab185633, EPR17671), FOXO1 (phospho Ser 253, ab131339; ab179450), mTOR (phospho Tyr 391, ab32028; ab2732)

(17) Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failureEuropean Journal of HistochemistryJuly 27, 2023Nan Li, Xue Fan, Lihong Liu, Yanbing Liu1:1000, ab219209; CD63, 1:1000, ab134045; PI3K, 1:1000, ab32089; p-PI3K, 1:1000, ab182651; Akt: 1:1000, ab38449; p-Akt: 1:1000, ab81283; GAPDH, 1:1000, ab9485; secondary antibody IgG: 1:2000, ab205718; all from Abcam). Statistical

(18) Neutrophil extracellular traps promote angiogenesis in gastric cancerCell communication and signaling : CCSJuly 21, 2023Yang S, Sun B, Li J, Li N, Zhang A, Zhang X, Yang H, Zou X.protein was then extracted, and the expression of ZO-1 (ab190085; Abcam), VE (ab33168; Abcam), AKT (ab38449; Abcam), p-AKT (ab8805; Abcam), mTOR, and p-mTOR (ab32028; Abcam) was analyzed via western blotting. Tubule

(19) Buyang Huanwu Decoction promotes the neurological recovery of traumatic spinal cord injury via inhibiting apoptosis, inflammation, and oxidative stressImmunity, Inflammation and DiseaseJuly 12, 2023Xu Li, Yingjun Song, Yang Yang, Guofu Zhangused in this study were listed as follows: anti‐IL‐6 antibody (ab233706, Abcam), anti‐pAKT antibody (ab38449, Abcam), anti‐gp130 antibody (ab227058, Abcam), anti‐pJAK2 antibody (ab32101, Abcam), anti‐pSTAT3 antibody

(20) Glucuronic acid metabolites of phenolic acids target AKT-PH domain to improve glucose metabolismChinese Herbal MedicinesJuly 1, 2023Jie Gao, Manqian Zhang, Xingwang Zu, Xue Gu, Erwei Hao, Xiaotao Hou, Gang Baipurchased from Cell Signaling Technology (Massachusetts, USA). Antibodies against p-AKT (phospho-T308, ab38449), p-AKT (phospho-S473, ab8932) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH, ab181602) were purchased

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Anti-AKT (phospho T308) antibody from Abcam

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Anti-AKT (phospho T308) antibody from Abcam

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