APC/Cyanine7 anti-human CD4 317418 from BioLegend

Product Specs
ItemAPC/Cyanine7 anti-human CD4
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number317418
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
IsotypeIgG2b, Kappa
Conjugate/TagAPC_CYANINE7
CloneOKT4
Quantity100 tests
HostMouse
ReactivityHuman, Cynomolgus, Rhesus
ApplicationsFlow Cytometry (FC)
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ClonalityMonoclonal
ImmunogenHuman peripheral T cells
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodiesCell ReportsMay 30, 2023Hailee R. Perrett, Philip J.M. Brouwer, Jonathan Hurtado, Maddy L. Newby, Lin Liu, Helena Müller-Kräuter, Sarah Müller Aguirre, Judith A. Burger, Joey H. Bouhuijs, Grace Gibson, et al.Anti-Human CD3,BD Biosciences,Cat# 557757; RRID: AB_396863 APC-Cy7 Mouse Anti-Human CD4,Biolegend,Cat# 317418; RRID: AB_571947 APC-Cy7 Mouse Anti-Human CD8,BD Biosciences,Cat# 557760; RRID: AB_396865 APC-H7 Mouse Anti-Human CD14

(2) Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly diseaseImmunityMarch 14, 2023Panpan Zhou, Ge Song, Hejun Liu, Meng Yuan, Wan-ting He, Nathan Beutler, Xueyong Zhu, Longping V. Tse, David R. Martinez, Alexandra Schäfer, et al.stain the PBMC samples for CD3 (APC-Cy7, BD Biosciences Cat# 557757), CD4 (APC-Cy7, BioLegend Cat# 317418), CD8 (APC-Cy7, BD Biosciences Cat# 557760), CD14 (APC-H7, BD Biosciences Cat# 561384), CD19 (PerCP-Cy5.5,

(3) Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytesJCI insightFebruary 8, 2023Zhang M, Chong KK, Chen ZY, Guo H, Liu YF, Kang YY, Li YJ, Shi TT, Lai KK, He MQ, et al.BioLegend), PerCP cy5.5 anti-human CX3CR1 (catalog 341614, BioLegend), APC cy/7 anti-human CD4 (catalog 317418, BioLegend), and PE anti-human TGFB1 (catalog 562260, BD Biosciences) (Supplemental Table 4). Flow cytometric analysis

(4) Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaquesbioRxivOctober 28, 2022Timothy N. Hoang, Elise G. Viox, Amit A. Upadhyay, Zachary Strongin, Gregory K. Tharp, Maria Pino, Rayhane Nchioua, Maximilian Hirschenberger, Matthew Gagne, Kevin Nguyen, et al.anti-FoxP3-AF647 (clone 150D; 5 μL; cat. # 320014), and anti-CD4-APC-Cy7 (clone OKT4; 2.5 μL; cat. # 317418) all from Biolegend; anti-CD38-FITC (clone AT1; 5 μL; cat. # 60131FI) from STEMCELL Technologies; and

(5) Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primatesNPJ vaccinesOctober 28, 2022Seenappa LM, Jakubowski A, Steinbuck MP, Palmer E, Haqq CM, Carter C, Fontenot J, Villinger F, McNeil LK, DeMuth PC.594, clone: 2H7, BioLegend cat# 302348, 1:20), anti-human CD4 (APC-Cy7, clone: OKT4, BioLegend cat# 317418, 1:20) and anti-human CXCR5 (PerCP-eF710, clone: MU5UBEE, ThermoFisher cat# 46-9185-42, 1:20). Cells

(6) Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe diseasebioRxivSeptember 28, 2022Panpan Zhou et al.stain the PBMC samples for CD3 (APC-Cy7, BD Pharmingen cat.# 557757), CD4 (APC-Cy7, Biolegend cat.# 317418), CD8 (APC-Cy7, BD Pharmingen cat.# 557760), CD14 (APC-H7, BD Pharmingen cat.# 561384), CD19 (PerCP-Cy5.5,

(7) Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like virusesbioRxivSeptember 16, 2022Wan-ting He et al.IgG+ B cells, PBMCs were stained for CD3 (APC Cy7, BD Pharmingen #557757), CD4 (APC-Cy7, Biolegend, #317418), CD8 (APC-Cy7, BD Pharmingen #557760), CD14 (APC-H7, BD Pharmingen #561384, clone M5E2), CD19 (PerCP-Cy5.5,

(8) Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaquesNature communicationsAugust 27, 2022Pino M, Pagliuzza A, Pampena MB, Deleage C, Viox EG, Nguyen K, Shim I, Zhang A, Harper JL, Samer S, et al.(clone M5E2, 5 μL, cat #564444), all from BD Biosciences; anti-CD4-APC-Cy7 (clone OKT4, 5 μL, cat #317418), anti-CD20-PerCP-Cy5.5 (clone 2H7, 5 μL, cat #302326), and anti-HLA-DR-BV711 (clone L243, 5 μL, cat

(9) Engineering extracellular vesicles by three‐dimensional dynamic culture of human mesenchymal stem cellsJournal of Extracellular VesiclesJune 18, 2022Xuegang Yuan, Li Sun, Richard Jeske, Dingani Nkosi, Sara B. York, Yuan Liu, Samuel C. Grant, David G. Meckes, Yan Li(BioLegend, 344748) for cytotoxic T cell proliferation assay, as well as anti‐CD4 antibody (BioLegend, 317418) for helper T cell proliferation assay. Samples were run on FACSCanto flow cytometer (BD Bioscences)

(10) Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like virusesNature immunologyJune 1, 2022He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, et al.IgG+ B cells, PBMCs were stained for CD3 (APC Cy7, BD Pharmingen #557757), CD4 (APC-Cy7, Biolegend, #317418), CD8 (APC-Cy7, BD Pharmingen #557760), CD14 (APC-H7, BD Pharmingen #561384, clone M5E2), CD19 (PerCP-Cy5.5,

(11) Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expressionCell ReportsMay 3, 2022Nida Meednu et al.605 anti-human CD27,Biolegend,Cat#302830; RRID:AB_2561450 APC/Cyanine7 anti-human CD4,Biolegend,Cat#317418; RRID:AB_571947 PE/Cyanine7 anti-human CD11c,Biolegend,Cat#301608; RRID:AB_389351 Alexa Fluor 647

(12) RNA polymerase II pausing factor NELF in CD8(+) T cells promotes antitumor immunityNature communicationsApril 20, 2022Wu B, Zhang X, Chiang HC, Pan H, Yuan B, Mitra P, Qi L, Simonyan H, Young CN, Yvon E, et al.NSG mice via the tail vein. Subsets of cells were expanded in vitro, stained by anti-CD4 (BioLegend, 317418), anti-CD8 (BioLegend, 344710), anti-CD45RA (BioLegend, 304112), and anti-CD62L (BioLegend, 304806),

(13) Isolation of Functional SARS-CoV-2 Antigen-Specific T-Cells with Specific Viral Cytotoxic Activity for Adoptive Therapy of COVID-19BiomedicinesMarch 9, 2022Estéfani García-Ríos, Alejandra Leivas, Francisco J. Mancebo, Laura Sánchez-Vega, Diego Lanzarot, José María Aguado, Joaquín Martínez-López, María Liz Paciello, Pilar Pérez-RomeroNumber CD3,UCHT1,PE/Cy7,Biolegend,351304 INF-γ,45-15,PE,Miltenyi Biotec,130-113-493 CD4,OKT4,APC/Cy7,BD Pharmingen,317418 CD8,SK1,PerCP/Cy5.5,Biolegend,344710 DAPI,,,Sigma-Aldrich (Merck),D9542 List of fluorochrome-labeled

(14) EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22PLoS pathogensJanuary 1, 2022Jorapur A, Marshall LA, Jacobson S, Xu M, Marubayashi S, Zibinsky M, Hu DX, Robles O, Jackson JJ, Baloche V, et al.

(15) Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodiesJournal for ImmunoTherapy of CancerJuly 29, 2021Gabrielle Leclercq et al.were washed twice in PBS (1500 rpm, 5 min, RT) and stained with the following markers: CD4 (APC-Cy7, 317418; Biolegend), CD8 (BV605, 344742; Biolegend), CD25 (BUV395, 564034; BD), CD69 (PE, 310306; Biolegend)

(16) CD101 genetic variants modify regulatory and conventional T cell phenotypes and functionsCell reports. MedicineJune 15, 2021Richert-Spuhler LE, Mar CM, Shinde P, Wu F, Hong T, Greene E, Hou S, Thomas K, Gottardo R, Mugo N, et al.

(17) Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infectionNature communicationsMay 19, 2021Song G, He WT, Callaghan S, Anzanello F, Huang D, Ricketts J, Torres JL, Beutler N, Peng L, Vargas S, et al.antibodies specific for the T-cell markers CD3 (APC-Cy7, BD Pharmingen #557757), CD4 (APC-Cy7, Biolegend #317418), and CD8 (APC-Cy7, BD Pharmingen #557760); B-cell markers CD19 (PerCP-Cy5.5, Fisher Scientific #NC9963455),

(18) Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2Cell reportsMay 11, 2021Zhou X, Ma F, Xie J, Yuan M, Li Y, Shaabani N, Zhao F, Huang D, Wu NC, Lee CD, et al.,BD Biosciences,Cat#557757; RRID: AB_396863 APC/Cy7 Anti-human CD4 antibody (Clone OKT4),BioLegend,Cat#317418; RRID: AB_571947 APC-Cy7 Anti-Human CD8 (Clone RPA-T8),BD Biosciences,Cat#557760; RRID: AB_396865) APC/Cy7

(19) Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysisCellMarch 4, 2021Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, et al.

(20) Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaquesCellJanuary 21, 2021Hoang TN, Pino M, Boddapati AK, Viox EG, Starke CE, Upadhyay AA, Gumber S, Nekorchuk M, Busman-Sahay K, Strongin Z, et al.anti-FoxP3-AF647 (clone 150D; 5 μL; cat. # 320014), and anti-CD4-APC-Cy7 (clone OKT4; 2.5 μL; cat. # 317418) all from Biolegend; anti-CD38-FITC (clone AT1; 5 μL; cat. # 60131FI) from STEMCELL Technologies; and

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7/18/2017Good Antibody For Human Lung CD4 Cells Rebecca GuyerOur lab digests human tissue to extract lymphocytes for studies that focus on memory T cell subsets. In our panel we need a CD4 marker that is dim since there are a plethora of CD4+ cells in our ... Read Review

APC/Cyanine7 anti-human CD4 from BioLegend

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APC/Cyanine7 anti-human CD4 from BioLegend

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