CD44 Polyclonal Antibody from Bioss Inc.

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Supplier Page from
Bioss Inc. for
CD44 Polyclonal Antibody

The CD44 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to CD44. This antibody recognizes Human, Mouse, Rat, and Rabbit antigen. The CD44 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.

Description

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events