The Rabbit Anti-Caspase-9 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP9, and Caspase 9. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Caspase-9 Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP)