Description
Product Characteristics:
Aliases: 110 kDa protein antibody, FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody, FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody, Rabenosyn-5 antibody, RBNS5_HUMAN antibody, Zfyve20 antibody, zinc finger FYVE domain containing 20 antibody, Zinc finger FYVE domain-containing protein 20 antibody
Target Information: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (By similarity)