Description
Product Characteristics: Function: Receptor for ATP that acts as a ligand gated ion channel. Subcellular location: Membrane, Multi-pass membrane protein.,P2X Receptors,P2RX3, P2X purinoceptor 3, ATP receptor, Purinergic receptor
Target Information: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]