Norrin Antibody AF3014 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNorrin Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF3014
NCBI Gene AliasesND, EVR2, FEVR
ApplicationsWestern Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction
Conjugate/TagUnconjugated
TargetNorrin
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
HostGoat
Quantity100 ug (also 25 ug)
NCBI Full Gene Namenorrin cystine knot growth factor NDP
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human Norrin, Lys25-Ser133, Accession # Q00604
ConcentrationLYOPH
PurityImmunogen affinity purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human Norrin in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Norrin is observed

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie diseaseEMBO Molecular MedicineOctober 11, 2023Valda Pauzuolyte, Aara Patel, James R Wawrzynski, Neil J Ingham, Yeh Chwan Leong, Rajvinder Karda, Maria Bitner‐Glindzicz, Wolfgang Berger, Simon N Waddington, Karen P Steel, et al.(1:5,000), Anti‐FLAG eBioscience 14‐6681‐80 (1:1,000), Anti‐GFP Abcam Ab6662 (1:1,000), Anti‐NDP R&D Systems AF3014 (1:1,000), overnight at 4°C, followed by washes in PBST and incubation with secondary antibodies at

(2) Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WntThe Journal of clinical investigationJune 1, 2020El-Sehemy A, Selvadurai H, Ortin-Martinez A, Pokrajac N, Mamatjan Y, Tachibana N, Rowland K, Lee L, Park N, Aldape K, et al.for Western blotting and IHC: anti-GAPDH (MilliporeSigma, CB1001, 1:5000), anti-Norrin (R&D Systems, AF3014, 1:500), anti-MYC (Abcam, ab9106, 1:1000), anti–β-catenin (Cell Signaling Technology, 9562, 1:1000),

(3) A novel signaling pathway regulates colon cancer angiogenesis through NorrinScientific reportsJuly 9, 2014Planutis K, Planutiene M, Holcombe RF.the manufacturers' recommendations (The protocol is provided at: http://www.rndsystems.com/Products/af3014/Applications). The antibody at the final concentration of 12.5 ug/ml for the wound-healing assay and

(4) Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cellsThe Journal of neuroscience : the official journal of the Society for NeuroscienceApril 28, 2010Seitz R, Hackl S, Seibuchner T, Tamm ER, Ohlmann A.

(5) Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in miceThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 6, 2010Ohlmann A, Seitz R, Braunger B, Seitz D, Bösl MR, Tamm ER.

Be the First to Write a Review!

Norrin Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (5)

Reviews

Norrin Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map