The Anti-C21orf2 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-C21orf2 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
CFAP410 (Cilia And Flagella Associated Protein 410) is a Protein Coding gene. Diseases associated with CFAP410 include Retinal Dystrophy With Or Without Macular Staphyloma and Spondylometaphyseal Dysplasia, Axial. CFAP410 interacted with NEK1, a kinase involved in DNA damage response. Knockdown of C21ORF2 caused defective DNA repair via homologous recombination, but not nonhomologous end joining, and C21ORF2-knockdown cells did not show defective activation of G2-phase DNA damage checkpoint. CFAP410 plays a role in the regulation of cell morphology and cytoskeletal organization. CFAP410 is necessary for maintenance of the differentiated chondrocyte phenotype