IL-23 p19 Antibody AF1619 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-23 p19 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF1619
NCBI Gene AliasesIL-23, p19
ApplicationsWestern Blot, Neutralization
Quantity50 ug (also 25 ug)
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
Conjugate/TagUnconjugated
ReactivityMouse
TargetIL-23
NCBI Full Gene Nameinterleukin 23, alpha subunit p19
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-23 p19, Met1-Ala196, Accession # Q9EQ14
ConcentrationLYOPH
PurityImmunogen affinity purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse IL-23 p19 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse IL-12/23 p40 is observed

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) T cell-directed IL-17 production by lung granular γδ T cells is coordinated by a novel IL-2 and IL-1β circuitMucosal ImmunologySeptember 1, 2018Antoine Ménoret, James A. Buturla, Maria M. Xu, Julia Svedova, Sanjeev Kumar, Vijay A. K. Rathinam, Anthony T. VellaPC-61.5.3) and rat isotype controls were purchased from Bio X Cell (West Lebanon, NH). Anti-IL-23 antibody (#AF1619) was purchased from R&D Systems (Minneapolis, MN). IL-1β, IL-2, and tumor necrosis factor (TNF) ELISA

(2) IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion InjuryJournal of immunology (Baltimore, Md. : 1950)October 15, 2017Geha M, Tsokos MG, Bosse RE, Sannikova T, Iwakura Y, Dalle Lucca JJ, De Waal Malefyt R, Tsokos GC.

(3) Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammationMucosal immunologySeptember 1, 2017Marks E, Naudin C, Nolan G, Goggins BJ, Burns G, Mateer SW, Latimore JK, Minahan K, Plank M, Foster PS, et al.institutional approvals. Recombinant IL-12p40 homodimer (#499-ML-025) and Mouse AntiIL-23 p19 Antibody (#AF1619) were obtained from R&D Systems (Minneapolis, MN, USA). Clinical samples. Mucosal biopsies and blood

(4) Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 SignalingClinical cancer research : an official journal of the American Association for Cancer ResearchJune 1, 2015Bowers JS, Nelson MH, Kundimi S, Bailey SR, Huff LW, Schwartz KM, Cole DJ, Rubinstein MP, Paulos CM.cytokine neutralization Neutralizing antibodies against murine IL-12p35 (MMp35A1.6; eBioscience) or IL-23p19 (AF1619; R&D systems) were used as previously published [13] or as prescribed on the website. Tumor-bearing

(5) Tristetraprolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory diseaseThe Journal of experimental medicineAugust 26, 2013Molle C, Zhang T, Ysebrant de Lendonck L, Gueydan C, Andrianne M, Sherer F, Van Simaeys G, Blackshear PJ, Leo O, Goriely S.were collected and analyzed for cytokines production using ELISA. Anti-IL23p19 (Polyclonal goat IgG, AF1619) and anti-IL12/23p40 (C17.8) antibodies were purchased from R&D Systems and BD, respectively. T cell

(6) Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatusInfection and immunityJanuary 1, 2012Gessner MA, Werner JL, Lilly LM, Nelson MP, Metz AE, Dunaway CW, Chan YR, Ouyang W, Brown GD, Weaver CT, et al.

(7) The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSFNature immunologyJune 1, 2011El-Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, Zhang GX, Dittel BN, Rostami A.Author Manuscript Biolegend. Neutralizing antibodies against IFN-γ (H22), IL-10 (AF-417-NA), IL-23p19 (AF1619) and IL-4 (AB-404-NA), all recombinant cytokines and Duoset ELISA kits used to quantify IL-17A, GM-CSF,

(8) RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiotaNature immunologyApril 1, 2011Sawa S, Lochner M, Satoh-Takayama N, Dulauroy S, Bérard M, Kleinschek M, Cua D, Di Santo JP, Eberl G.

(9) Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapyThe Journal of experimental medicineMarch 14, 2011Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, et al.Zurich, Switzerland). Neutralizing antibodies for IL-17A (MAB421), IFN-γ (XMG1.2), CCL20 (MAB760), IL-23 (AF1619), IL-23R (MAB1686), IL-6 (MAB406), and IL-22 (AF582) were purchased from R&D Systems. CpG oligodeoxynucleotide

(10) The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone lossJournal of immunology (Baltimore, Md. : 1950)January 15, 2011Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G.

(11) Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune diseaseNature medicineFebruary 1, 2010Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, et al.

(12) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma productionProceedings of the National Academy of Sciences of the United States of AmericaApril 7, 2009Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA Jr, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, et al.

(13) Tumor-specific Th17-polarized cells eradicate large established melanomaBloodJuly 15, 2008Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, et al.

(14) Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infectionJournal of immunology (Baltimore, Md. : 1950)March 15, 2008Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, et al.

(15) Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challengeProceedings of the National Academy of Sciences of the United States of AmericaOctober 2, 2007He R, Oyoshi MK, Jin H, Geha RS.

(16) TLR3 and TLR7 are involved in expression of IL-23 subunits while TLR3 but not TLR7 is involved in expression of IFN-beta by Theiler's virus-infected RAW264.7 cellsMicrobes and infectionSeptember 1, 2007Al-Salleeh F, Petro TM.

(17) Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivoJournal of immunology (Baltimore, Md. : 1950)August 15, 2007Hajishengallis G, Shakhatreh MA, Wang M, Liang S.

(18) T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunityJournal of immunology (Baltimore, Md. : 1950)February 1, 2007Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE.

Be the First to Write a Review!

IL-23 p19 Antibody

IL-23 p19 Antibody

IL-23 p19 Antibody

IL-23 p19 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (18)

Reviews

IL-23 p19 Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map