GABA-A R gamma 2 Antibody NB300-190 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemGABA-A R gamma 2 Antibody
CompanyNovus Biologicals, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberNB300-190
ImmunogenFusion protein from the cytoplasmic loop of the gamma 2 subunit. Accession # P18508
NCBI Gene AliasesCAE2, FEB8, DEE74, EIEE74, ECA2, GEFSP3
Format10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Quantity0.1 ml
ApplicationsWestern Blot, Immunohistochemistry, Knockdown Validated
ReactivityHuman, Mouse, Rat
Conjugate/TagUnconjugated
HostRabbit
TargetGABA-A R gamma 2
NCBI Full Gene Namegamma-aminobutyric acid type A receptor subunit gamma 2, gamma-aminobutyric acid type A receptor subunit gamma2
Brand/TrademarkNovus Biologicals, a Bio-Techne Brand
ClonalityPolyclonal
PurityAntigen Affinity-purified
Molecular Weight46 kDa
Research AreaNeuronal Cell Markers, Neuroscience, Neurotransmission
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at -20C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

Specificity: Specific for endogenous levels of the ~46 kDa gamma 2-subunit of the GABAA receptor

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: http://www.novusbio.com

(1) Allosteric potentiation of GABA(A) receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasisCell reportsNovember 1, 2022Chan ES, Ge Y, So YW, Bai YF, Liu L, Wang YT.

(2) Interferon-γ enhances neocortical synaptic inhibition by promoting membrane association and phosphorylation of GABA_A receptors in a protein kinase C-dependent mannerBrain, behavior, and immunityMarch 1, 2022Janach GMS, Böhm M, Döhne N, Kim HR, Rosário M, Strauss U.

(3) 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feedingMolecular psychiatryDecember 1, 2021He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, et al.immunofluorescent staining for γ2 and 5-HT. Briefly, sections were incubated with primary rabbit anti-γ2 antibody (1:100, NB300-190, Novus Biologicals) and primary goat anti-5-HT antibody (1:5000, 20079, ImmunoStar) overnight, followed

(4) Paraventricular hypothalamus mediates diurnal rhythm of metabolismNature communicationsJuly 30, 2020Kim ER, Xu Y, Cassidy RM, Lu Y, Yang Y, Tian J, Li DP, Van Drunen R, Ribas-Latre A, Cai ZL, et al.with cardiac perfusion, except mentioned otherwise in the text. Primary antibody against γ2 (1:100, NB300-190, Novus Biologicals), BMAL1 (1:200, NB100-2288, Novus Biologicals), c-Fos (1:1000, #2250, Cell Signaling Technology

(5) The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse FormationCell reportsNovember 19, 2019Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, et al.

(6) Metformin produces anxiolytic-like effects in rats by facilitating GABA_A receptor trafficking to membraneBritish journal of pharmacologyJanuary 1, 2019Fan J, Li D, Chen HS, Huang JG, Xu JF, Zhu WW, Chen JG, Wang F.

(7) Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neuronsNeuropharmacologyJune 1, 2016Bohnsack JP, Carlson SL, Morrow AL.anti-GABAA β3 (Novus, #NBP1-47613, 1:1000), anti-GABAA δ (Novus, #3002-200, 1:750), anti-GABAA γ2 (Novus, #NB300-190, 1:1000), anti-GABAA phospho-γ2 (Ser327)(PhosphoSolutions, p1130-327, 1:1000), anti-GABAA phosphor-β3 (Novus,

(8) Brief Dark Exposure Reduces Tonic Inhibition in Visual CortexThe Journal of neuroscience : the official journal of the Society for NeuroscienceDecember 2, 2015Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A.

(9) GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feedingThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 25, 2015Wu Z, Kim ER, Sun H, Xu Y, Mangieri LR, Li DP, Pan HL, Xu Y, Arenkiel BR, Tong Q.For immunohistochemistry studies, we used a previously described protocol (Xu et al., 2012). Primary antibody against ␥2 (NB300-190, Novus Biologicals) was used. Sections were visualized and photographed with a TCS SP5 confocal microscope

(10) The Contribution of Normal Pregnancy to EclampsiaPloS oneJanuary 1, 2015Johnson AC, Nagle KJ, Tremble SM, Cipolla MJ.

(11) Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autismJournal of autism and developmental disordersAugust 1, 2014Fatemi SH, Reutiman TJ, Folsom TD, Rustan OG, Rooney RJ, Thuras PD.

(12) Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKANeurochemical researchJune 1, 2014Carlson SL, O'Buckley TK, Thomas R, Thiele TE, Morrow AL.

(13) Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across developmentPloS oneJanuary 1, 2013Bleckert A, Parker ED, Kang Y, Pancaroglu R, Soto F, Lewis R, Craig AM, Wong RO.Tris-buffered saline/0.05% Tween-20. Membranes were incubated with primary (anti-GABAAR γ2, Novus Biologicals NB300-190 or anti-GFP, Rockland 600-401-215) and secondary (HRP conjugated, Millipore) antibodies, and signal

(14) A mouse monoclonal antibody against the γ2 subunit of GABAA receptorsHybridoma (2005)December 1, 2011Joshi S, Sun C, Kapur J.Sieghart(7,8) (Medical University, Vienna, Austria), Millipore antibody Ab5954 (Billerica, MA), Novus antibody NB300-190 (Littleton, CO), and Alpha Diagnostics antibody GAG21-A (San Antonio, TX). However, all of these are

(15) Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsyEpilepsy researchJune 1, 2011Kharlamov EA, Lepsveridze E, Meparishvili M, Solomonia RO, Lu B, Miller ER, Kelly KM, Mtchedlishvili Z.

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GABA-A R gamma 2 Antibody

GABA-A R gamma 2 Antibody

GABA-A R gamma 2 Antibody

GABA-A R gamma 2 Antibody from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (15)

Reviews

GABA-A R gamma 2 Antibody from Novus Biologicals, a Bio-Techne Brand

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