CLOCK (D45B10) Rabbit mAb 5157S from Cell Signaling Technology

Product Specs
ItemCLOCK (D45B10) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number5157S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, Mk
TargetCLOCK
HostRabbit
NCBI Gene AliasesKAT13D, bHLHe8
ClonalityMonoclonal
NCBI Full Gene Nameclock circadian regulator
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneD45B10
Molecular Weight100

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesisNature cell biologyJuly 1, 2023Alkhoury C, Henneman NF, Petrenko V, Shibayama Y, Segaloni A, Gadault A, Nemazanyy I, Le Guillou E, Wolide AD, Antoniadou K, et al.immunofluorescence imaging (Cell Signaling Technology, 14020S)), anti-Clock (1:1,000; Cell Signaling Technology, 5157), anti-HIS-Tag (1:1,000; Proteintech, 66005-12-Ig), anti-IPOA5 (1:1,000; Proteintech, 18137-1-AP), anti-Cry1

(2) Circadian regulator CLOCK promotes tumor angiogenesis in glioblastomaCell reportsFebruary 28, 2023Pang L, Dunterman M, Xuan W, Gonzalez A, Lin Y, Hsu WH, Khan F, Hagan RS, Muller WA, Heimberger AB, et al.indicated companies, including b-actin (Sigma, #A3854), Vinculin (EMD Millipore, #05-386), CLOCK (CST, #5157S), BMAL1 (CST, #14020S), OLFML3 (Fisher, #PA5-31581), POSTN (Novus, #NBP1-30042), TBK1 (CST, #3504),

(3) Berberine increases stromal production of Wnt molecules and activates Lgr5(+) stem cells to promote epithelial restitution in experimental colitisBMC biologyDecember 17, 2022Luo Z, Li Z, Liang Z, Wang L, He G, Wang D, Shen L, Wang Z, Ma X, Geng F, et al.(Cell Signaling, 9272), β-Actin (Santa Cruz, 47778), Arntl (Cell Signaling, 14020), Clock (Cell Signaling, 5157), IL-6 (abcam, 229381), TNFα (Cell Signaling, 11948), Wnt6 (abcam, 154144), Wnt10a (abcam, 106522),

(4) Core clock regulators in dexamethasone-treated HEK 293T cells at 4 h intervalsBMC Research NotesDecember 1, 2022Rafailia A. A. Beta, Zoi V. Arsenopoulou, Amalia Kanoura, Dimitrios Dalkidis, Rafaela Avraamidou, Nikolaos A. A. Balatsosand probed using the following antibodies: BMAL1 (#14020, 1:1000, Cell Signaling Technology), CLOCK (#5157, 1:500, Cell Signaling Technology) and β-ACTIN (A5441, 1:5000, Sigma-Aldrich). β-ACTIN was used as a

(5) Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesisCell ReportsOctober 18, 2022Rebekah Brooks, Judith Monzy, Bailey Aaron, Xue Zhang, Andrew Kossenkov, James Hayden, Frederick Keeney, David W. Speicher, Lin Zhang, Chi V. Dang,Cell Signaling,Cat#:14020; RRID:AB_2728705 Rabbit monoclonal anti-CLOCK (clone D45B10),Cell Signaling,Cat#:5157; RRID:AB_10695411 Mouse monoclonal anti-PBRM1 (clone E6N2K),Cell Signaling,Cat#:81832 Rabbit monoclonal

(6) Regulation of Circadian Genes Nr1d1 and Nr1d2 in Sex-Different Manners during Liver AgingInternational Journal of Molecular SciencesSeptember 2, 2022Sang Gyun Noh, Hee Jin Jung, Seungwoo Kim, Radha Arulkumar, Dae Hyun Kim, Daeui Park, Hae Young Chung(sc-47778) were purchased from Santa Cruz (Santa Cruz Biotechnology, Santa Cruz, CA, USA). Clock antibody (#5157) was obtained from Cell Signaling Technology (Danvers, MA, USA), and secondary antibodies (GTX213110-01,

(7) Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1SSRN Electronic JournalAugust 24, 2022Miriam Toledo, Elena Tarabra, Ana Batista-Gonzalez, Paola Merlo, Daorong Feng, Jaakko Sarparanta, Francesco Botrr, Jeffrey E. Pessin, Rajat SinghCell Signaling Technology Cat# 14020; RRID: AB_2728705 Rabbit monoclonal anti-CLOCK Cell Signaling Technology Cat# 5157; RRID:AB_10695411 Rabbit polyclonal anti-CRY1 Origene Cat# TA342728 Rabbit polyclonal anti-CRY2 Abcam Cat#

(8) Chrono-Aerobic Exercise Optimizes Metabolic State in DB/DB Mice through CLOCK-Mitophagy-ApoptosisInternational journal of molecular sciencesAugust 18, 2022Zhang Z, Li X, Zhang J, Du J, Zhang Q, Ge Z, Ding S.antibodies were diluted for immunoblotting: monoclonal antibody to GLUT4 (2213S, CST, 1:50), CLOCK (5157, CST, 1:50) and polyclonal antibody to BMAL1 (ARNTL) (14268-1-AP, Proteintech, 1:100). Polyclonal antibodies

(9) Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interactionNature CommunicationsJuly 9, 2022Yang An, Baoshi Yuan, Pancheng Xie, Yue Gu, Zhiwei Liu, Tao Wang, Zhihao Li, Ying Xu, Yi Liuantibodies: CK1δ (Abcam, ab85320, 1:1000), PER1 (MBL, PM091, 1:1000), PER2 (MBL, PM083, 1:1000), CLOCK (CST, 5157 S, 1:500), GFP (Sigma-Aldrich, G1544, 1:1000), Flag (Sigma-Aldrich, F1804, 1:1000), HA (Sigma-Aldrich,

(10) Shumian Capsule Improves the Sleep Disorder and Mental Symptoms Through Melatonin Receptors in Sleep-Deprived MiceFrontiers in PharmacologyJuly 8, 2022Wenhua Li, Yinlong Cheng, Yi Zhang, Yazhi Qian, Mo Wu, Wei Huang, Nan Yang, Yanyong Liunormalized against the internal control β-actin. Antibodies against β-actin (Cat. No. 4970), clock (Cat. No. 5157), CaMKⅡ (Cat. No. 3362), and p-CREB (Ser133) (Cat. No. 9198) were purchased from Cell Signaling Technology

(11) The association between disruption of the circadian rhythm and aggravation of colitis in miceGastroenterology reportJanuary 1, 2022Chen YD, Zhao RF, Zheng G, Ling FM, Li JR, Xu MY, Guo D, Zhang QL, Li S, Zhu LR.Antibody,Company,Catalog,Specificity,Host,Dilution Bmal1,Cell Signaling Technology,14020S,Mouse,Rabbit,"1:1,000" Clock,Cell Signaling Technology,5157s,Mouse,Rabbit,"1:1,000" Nr1d1,Cell Signaling Technology,13418S,Mouse,Rabbit,"1:1,000" Cry1,Abcam,Ab171860,Mouse,Rabbit,"1:1,000" Cry2,Proteintech,13997-1-AP,Mouse,Rabbit,1:500 Per1,Proteintech,13463-1-AP,Mouse,Rabbit,1:500 Per2,ABclonal,A5107,Mouse,Rabbit,1:500 Per2,Abcam,ab179813,Human,Rabbit,"1:1,000" DRP1,Cell Signaling Technology

(12) Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regenerationCell researchFebruary 1, 2021Liang C, Liu Z, Song M, Li W, Wu Z, Wang Z, Wang Q, Wang S, Yan K, Sun L, et al.aging-associated degenerative disorders. Materials and methods Antibodies For western blotting: anti-CLOCK (#5157, 1:1,000), anti-HP1α (#2616S, 1:1,000) and anti-HP1γ (#2619, 1:3,000) from Cell Signaling Technology;

(13) Effects of tannase-converted green tea extract on skeletal muscle developmentBMC Complementary Medicine and TherapiesDecember 1, 2020Ki-Bae Hong, Hee-Seok Lee, Jeong Sup Hong, Dong Hyeon Kim, Joo Myung Moon, Yooheon Parksecondary antibody (horseradish peroxide (HRP) conjugated IgG secondary antibody (Cell Signaling, #5157, 1:2000) was diluted 1: 1000 times, allowed to react for 2 h at 4 °C, washed three times with TBST,

(14) Exercise Training Impacts Skeletal Muscle Clock in Adults with PrediabetesMedicine & Science in Sports & ExerciseOctober 1, 2020MELISSA L. ERICKSON, HUI ZHANG, JACOB T. MEY, JOHN P. KIRWANSignaling Technology, 1:1000, catalog no. 1402S), CLOCK (Cell Signaling Technology, 1:1000, catalog no. 5157S), PER 1 (Santa Cruz Technology, 1:500, catalog no. sc-398890), PER2 (Abcam, 1:500, catalog no. ab179813),

(15) Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6CellsAugust 8, 2020Chhunchha B, Kubo E, Singh DP.membranes were probed with anti-Bmal1 (sc-365645, Santa Cruz Biotechnology, Dallas, TX, USA); anti-Clock (#5157S, Cell Signaling Technology, Danvers, MA, USA); Anti-Nrf2 (sc-365949 Santa Cruz Biotechnology); Anti-Nrf2

(16) Creatine and taurine mixtures alleviate depressive-like behaviour in Drosophila melanogaster and mice via regulating Akt and ERK/BDNF pathwaysScientific reportsJuly 9, 2020Kim S, Hong KB, Kim S, Suh HJ, Jo K.incubated for 1 h at 25 °C with horseradish peroxide-conjugated IgG secondary antibody (Cell Signaling, #5157, 1:2000). Signals were developed using ECL Prime (GE Healthcare Life Sciences, CT, USA) on a FluorChem

(17) Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor MicroenvironmentCancer discoveryMarch 1, 2020Chen P, Hsu WH, Chang A, Tan Z, Lan Z, Zhou A, Spring DJ, Lang FF, Wang YA, DePinho RA.indicated companies, including β-actin (Sigma, #A3854), Vinculin (EMD Millipore, #05–386), CLOCK (CST, #5157S), BMAL1 (CST, #14020S) and OLFML3 (Invitrogen, #PA5–31581). Immunohistochemistry and immunofluorescence Immunohistochemistry

(18) Role and mechanism of PTEN in Burkitt's lymphomaOncology ReportsJanuary 9, 2020Chuntuan Li, Yahong Xu, Pengliang Xin, Yan Zheng, Xiongpeng Zhuanti-PTEN, anti-AKT, anti-pAKT, anti-Bad, anti-Bax, anti-P53, anti-P21, anti-CDK4 and anti-CDK6 were #5157, #9188, #4685, #4060, #9268, #5023, #2527, #2947, #12790, #13331, respectively. Anti-cyclin D3, and

(19) Role of Phosphorylated Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) in the Regulation of Germ Cell Specific mRNAs in Chromatoid Bodies During SpermatogenesisFrontiers in cell and developmental biologyJanuary 1, 2020Anbazhagan R, Kavarthapu R, Coon SL, Dufau ML.circadian locomotor output cycles protein kaput (CLOCK) rabbit monoclonal antibody (1:500 dilution; cst#5157; Cell Signaling), Ybx3 mouse monoclonal antibody (1:500 dilution; LS-C105064; LS Bio), PRM1 rabbit polyclonal

(20) Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast CellsInternational Journal of Molecular SciencesOctober 17, 2019Kazuki Yoshida, Makoto Tajima, Tomoki Nagano, Kosuke Obayashi, Masaaki Ito, Kimiko Yamamoto, Isao MatsuokaCell Signaling Technology (Danvers, MA, USA). ONO-DI-004 (selective EP1 agonist), Int. J. Mol. Sci. 2019, 20, 5157 12 of 15 ONO-AE1-259-01 (selective EP2 agonist), ONO-AE-248 (selective EP3 agonist), and ONO-AE1-329 (selective

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CLOCK (D45B10) Rabbit mAb

CLOCK (D45B10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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CLOCK (D45B10) Rabbit mAb from Cell Signaling Technology

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