Rabbit Anti-Alkaline Phosphatase/PLAP Antibody MBS4380566 from MyBioSource.com

Product Specs
ItemRabbit Anti-Alkaline Phosphatase/PLAP Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380566
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsImmunohistology (Formalin-Fixed)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ReactivityHuman. Others not known
TargetAlkaline Phosphatase/PLAP
IsotypeIgG
Molecular Weight70kDa
CloneALPP/2899R
HostRabbit
ImmunogenReacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease
NCBI Full Gene Namealkaline phosphatase, placental
NCBI Gene AliasesPALP, PLAP, ALP, PLAP-1
ClonalityMonoclonal