InVivoMab anti-mouse CD3ε F(ab')2 fragment BE0001-1FAB-R005mg from Bio X Cell

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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(1) Membrane-bound Dickkopf-1 in Foxp3⁺ regulatory T cells suppresses T-cell-mediated autoimmune colitisImmunologyOctober 1, 2017Wook-Jin Chae, Jong-Hyun Park, Octavian Henegariu, Saliha Yilmaz, Liming Hao, Alfred L. M. Bothwell

(2) The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4⁺ T cellsFrontiers in immunologyJanuary 1, 2017Besançon A, Baas M, Goncalves T, Valette F, Waldmann H, Chatenoud L, You S.

(3) The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic miceJournal of autoimmunityMay 1, 2015Sarikonda G, Sachithanantham S, Miller JF, Pagni PP, Coppieters KT, von Herrath M.

(4) Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulationJournal of immunology (Baltimore, Md. : 1950)March 1, 2015Valle A, Barbagiovanni G, Jofra T, Stabilini A, Perol L, Baeyens A, Anand S, Cagnard N, Gagliani N, Piaggio E, et al.

(5) Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulationEuropean journal of immunologyJune 1, 2014Shiheido H, Aoyama T, Takahashi H, Hanaoka K, Abe T, Nishida E, Chen C, Koga O, Hikida M, Shibagaki Y, et al.

(6) CD3 antibody and IL-2 complex combination therapy inhibits atherosclerosis by augmenting a regulatory immune responseJournal of the American Heart AssociationApril 22, 2014Kasahara K, Sasaki N, Yamashita T, Kita T, Yodoi K, Sasaki Y, Takeda M, Hirata K.

(7) Regression of atherosclerosis with anti-CD3 antibody via augmenting a regulatory T-cell response in miceCardiovascular researchApril 1, 2014Kita T, Yamashita T, Sasaki N, Kasahara K, Sasaki Y, Yodoi K, Takeda M, Nakajima K, Hirata K.

(8) Testing agents for prevention or reversal of type 1 diabetes in rodentsPloS oneJanuary 1, 2013Grant CW, Moran-Paul CM, Duclos SK, Guberski DL, Arreaza-Rubín G, Spain LM.

(9) Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cellsJournal of immunology (Baltimore, Md. : 1950)December 1, 2000Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C.

InVivoMab anti-mouse CD3ε F(ab')2 fragment