The Anti-NUMB Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to NUMB. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-NUMB Rabbit Monoclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage