The Rabbit Anti-Aconitase 1 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to ACO1, and Aconitase 1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Aconitase 1 Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding