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Antibodies
Anti-BRCA1 antibody [MS110]
Anti-BRCA1 antibody [MS110] from Abcam
Be the first to write a review!
Citations:
(51)
Supplier Page
Supplier Page from
Abcam for
Anti-BRCA1 antibody [MS110]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-BRCA1 antibody [MS110]
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab16780
Quantity
10 UG, 100 UG
Applications
Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunohistochemistry (Frozen sections), Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunohistochemistry (Frozen sections), Immunoprecipitation
Conjugate/Tag
Unconjugated
Host
Mouse, Nude mouse
Antibody Type
Primary
Clonality
Monoclonal
Clone
MS110
Research Area
Epigenetics
Gene Name
BRCA1
Target
BRCA1
Reactivity
Human (Hu)
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (51)
(1)
RAD54L regulates replication fork progression and nascent strand degradation in BRCA1/2-deficient cells
bioRxiv
July 29, 2023
Mollie E. Uhrig, Neelam Sharma, Petey Maxwell, Platon Selemenakis, Claudia Wiese
Cell Signaling
;
1:6,000
) α-FBH1 (sc-81563;
1:100
), α-BRCA2 (OP95; EMD Millipore;
1:500
), α-BRCA1 (MS110;
ab16780
;
Abcam
;
1:50
), α-
PCNA
(
sc-25280
;
Santa Cruz Biotechnology
;
1:1,000
), α-NUCKS1 ([41];
1:10,000
). HRP-conjugated
(2)
LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer
BMC Cancer
February 8, 2023
Zhipeng Du, Fangxiao Zhang, Lei Liu, Hui Shen, Tingting Liu, Jing Jin, Nanxi Yu, Zhijie Wan, Hang Wang, Xuguang Hu,
et al.
Triton X-100 on ice for 15 min. After blockage, cells were stained with anti-
BRCA1
antibody (
1:200
,
ab16780
,
Abcam
) or anti-
Rad51
antibody (
1:250
,
ab133534
, Abcam) and then with the secondary antibody. Cellular
(3)
XPF activates break-induced telomere synthesis
Nature communications
October 2, 2022
Guh CY, Shen HJ, Chen LW, Chiu PC, Liao IH, Lo CC, Chen Y, Hsieh YH, Chang TC, Yen CP,
et al
.
cat#
MABC545
, dilution
1:1,000
), γH2AX (
Cell Signaling
, cat#
9718
T, dilution
1:1,000
), BRCA1 (
Abcam
, cat#
ab16780
, dilution
1:1,000
),
SLX4
(
Bethyl Laboratories
, cat#
A302-269A
, dilution
1:1,000
),
CSB
(
Bethyl Laboratories
,
(4)
Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification
Cancer research
April 15, 2022
Pellegrino B, Herencia-Ropero A, Llop-Guevara A, Pedretti F, Moles-Fernández A, Viaplana C, Villacampa G, Guzmán M, Rodríguez O, Grueso J,
et al
.
10802-1-AP
,
1:400
), mouse anti-BRCA1 (
Santa Cruz Biotechnology
sc-6954
,
1:50
), mouse anti-BRCA1 (
Abcam
ab16780
,
1:200
),
mouse
anti-phospho-H2AX (
Millipore
#
05-636
,
1:200
). Goat anti-rabbit Alexa fluor 568 (Invitrogen;
(5)
2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity
Cell reports
January 11, 2022
Kusi M, Zand M, Lin LL, Chen M, Lopez A, Lin CL, Wang CM, Lucio ND, Kirma NB, Ruan J,
et al
.
(Lys79),Boster Biological Technology,Cat# CI1046
Mouse
monoclonal anti-BRCA1 (
Clone
MS110),
Abcam
,Cat#
ab16780
Mouse
monoclonal anti-
MSH2
(
Clone
3A2B8C),
Abcam
,Cat#
ab52266
Mouse
monoclonal anti-
XRCC2
(
Clone
EPR5149),
Abcam
,Cat#
(6)
Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy
Journal of Experimental & Clinical Cancer Research
December 1, 2021
Xin Peng et al.
12712
), γH2AX (
Abcam
,
ab81299
),
BRCA1
(
Cell Signaling Technology
,
14823
,
for Western blot
),
BRCA1
(
Abcam
,
ab16780
,
for IHC
),
BRCA2
(
Abcam
,
ab216972
), Rad51 (Abcam, 133534), phospho-ATM (S1981,
Abcam
,
ab81292
),
Ki-67
(7)
Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
eLife
June 18, 2021
McMahon KA, Stroud DA, Gambin Y, Tillu V, Bastiani M, Sierecki E, Polinkovsky ME, Hall TE, Gomez GA, Wu Y,
et al
.
sc-642
, RRID:AB_630944, WB
1:500
, IF
1:100
, PLA
1:100
), mouse anti-BRCA1 MS110 antibody (
Abcam
, Cat#
ab16780
, RRID:AB_2259338, WB
1:1000
, IF
1:100
, PLA
1:100
), mouse-anti-BRCA1 D-9 antibody (
Santa Cruz
, Cat#
sc-6964
,
(8)
SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
Cell Reports
March 30, 2021
Elizabeth V. Minten, Priya Kapoor-Vazirani, Chunyang Li, Hui Zhang, Kamakshi Balakrishnan, David S. Yu
Prism 7 using a one-sample t test. Antibodies and reagents The following antibodies were used:
BRCA1
(
ab16780
,
Abcam
: 1/1000 for western and 1/200 for IF) and (
sc-6954
,
Santa Cruz Biotechnology
: 1/300 for western).
(9)
Lung gene expression signatures suggest pathogenic links and molecular markers for pulmonary tuberculosis, adenocarcinoma and sarcoidosis
Communications biology
October 23, 2020
Chai Q, Lu Z, Liu Z, Zhong Y, Zhang F, Qiu C, Li B, Wang J, Zhang L, Pang Y,
et al
.
immunohistochemical staining
), anti-
MMP8
(#
sc-514803
,
Santa Cruz
,
1:100
for
immunohistochemical staining
), anti-BRCA1 (#
ab16780
,
Abcam
,
1:100
for
immunohistochemical staining
), anti-
PCNA
(#
sc-25280
,
Santa Cruz
,
1:100
for
immunohistochemical staining
(10)
IGF1R Axis Inhibition Restores Dendritic Cell Antitumor Response in Ovarian Cancer
Translational Oncology
August 1, 2020
Lina Somri-Gannam, Shilhav Meisel-Sharon, Shay Hantisteanu, Gabriel Groisman, Ofer Limonad, Mordechai Hallak, Ilan Bruchim
used:
IGF1R
(
sc-81167
,
Santa Cruz Biotechnology, Inc
.), p53 (M7001, DAKO), Ki67 (M 7240, DAKO), BRCA1 (
ab16780
,
Abcam
),
CD141
(
ab109189
,
Abcam
), and
CD1c
(
ab156708
,
Abcam
). Slides were then counterstained with hematoxylin
(11)
Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells
Cell death & disease
July 24, 2020
Zhai B, Li Y, Kotapalli SS, Bacha J, Brown D, Steinø A, Daugaard M.
Signaling Technology); ɣH2AX (
05–636
,
MilliporeSigma
, Oakville, Canada); cyclin A2 (
ab16726
,
Abcam
);
BRCA1
(
ab16780
,
Abcam
); Rad51 (H8349, Santa Cruz Biotechnology);
RPA32
(
ab2175
, Abcam);
donkey
anti-rabbit Alexa-Fluor
(12)
Olaparib and enzalutamide synergistically suppress HCC progression via the AR‐mediated miR‐146a‐5p/BRCA1 signaling
The FASEB Journal
April 1, 2020
Jie Zhao, Yin Sun, Hui Lin, Fuju Chou, Yao Xiao, Ren'an Jin, Xiujun Cai, Chawnshang Chang
by
incubation
with HRP-conjugated secondary antibody (Dako) for 60 min at room temperature. BRCA1 (
ab16780
,
Abcam
, Cambridge, MA), Ki67 (
ab16667
,
Abcam
) and cleaved caspase-3 (
ab2302
,
Abcam
) antibodies were
(13)
DNA damage induced during mitosis undergoes DNA repair synthesis
PloS one
January 1, 2020
Gomez Godinez V, Kabbara S, Sherman A, Wu T, Cohen S, Kong X, Maravillas-Montero JL, Shi Z, Preece D, Yokomori K,
et al
.
laser. Scale bar = 10μ m. (E and F) BRCA1 immunostaining using two different antibodies. (E) BRCA1
ab16780
antibody (
Abcam
). (F) BRCA1 OP107 antibody (Calbiochem). (F-G) show the localization of BRCA1 and 53BP1
(14)
Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies
Brain Sciences
December 20, 2019
Masanori Kurihara, Tatsuo Mano, Yuko Saito, Shigeo Murayama, Tatsushi Toda, Atsushi Iwata
Can Get Signal Solution 1 (Toyobo, Osaka, Japan) overnight at 4 ◦ C. Anti-BRCA1 (MS110;
Abcam
; Cat#
ab16780
;
1:1000
), anti-human Tau (HT7;
Thermo Fisher Scientific
; Cat#
MN1000
;
1:2000
), and anti-actin (C4;
Merck Millipore
(15)
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer
Breast cancer research : BCR
August 7, 2019
Tan X, Li Z, Ren S, Rezaei K, Pan Q, Goldstein AT, Macri CJ, Cao D, Brem RF, Fu SW.
vimentin (
5741
,
1:200
Cell Signaling), anti-rabbit E-cadherin (
3195
,
1:200
, Cell Signaling), anti-BRCA1 (
ab16780
,
1:500
,
Abcam
), Alexa Flour 568 goat anti-mouse IgG (
1:500
, Invitrogen), and Alexa Flour 568 goat anti-mouse
(16)
Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation
Cell Death & Differentiation
May 1, 2019
SeoYoung Kim, Hee Jin, Hang-Rhan Seo, Hae June Lee, Yun-Sil Lee
Sciences.
Immunohistochemistry
Immunohistochemistry
was performed with the following antibodies:
BRCA1
(
ab16780
,
Abcam
) or
CTSS
(
sc-271619
,
Santa Cruz Biotechnology
) and
mouse
anti-Ki-67 (M7248, Dako).
Human
breast cancer
(17)
A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation
EMBO molecular medicine
December 1, 2018
Castroviejo-Bermejo M, Cruz C, Llop-Guevara A, Gutiérrez-Enríquez S, Ducy M, Ibrahim YH, Gris-Oliver A, Pellegrino B, Bruna A, Guzmán M,
et al
.
10802‐1‐AP
,
1:400
), mouse anti‐BRCA1 (
Santa Cruz Biotechnology
sc‐6954
,
1:50
), mouse anti‐BRCA1 (
Abcam
ab16780
,
1:200
),
mouse
anti‐γ‐H2AX (
Millipore
#
05‐636
,
1:200
), rabbit anti‐
53BP1
(
Cell Signalling
#
4937
,
1:100
).
(18)
Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination
Cell death & disease
October 3, 2018
Zhai B, Steinø A, Bacha J, Brown D, Daugaard M.
2577
); cyclin A2 (
Abcam
,
ab16726
); ɣH2AX (
EMD Millipore
, Etobicoke, Canada,
05-636
); BRCA1 (
Abcam
,
ab16780
); Rad51 (Santa Cruz Biotechnology, H8349);
RPA32
(Abcam,
ab2175
);
donkey
anti-rabbit Alexa-Fluor 594
(19)
Effect of lanthanum chloride on tumor growth and apoptosis in human ovarian cancer cells and xenograft animal models
Experimental and Therapeutic Medicine
June 13, 2018
Fen Wang, Yuanfang Zhu, Shanyu Fang, Shuya Li, Sisun Liu
B-cell lymphoma
-2 (BCL-2; cat. no. ab692;
1:500
), Ki67 (cat. no.
ab15580
,
1:500
), breast cancer 1 (BRCA1; cat. no.
ab16780
;
1:500
), BRCA2 (cat. no.
ab27976
;
1:500
) and excision repair cross-complementation group 1 (ERCC1; cat.
(20)
β‑catenin nuclear translocation induced by HIF‑1α overexpression leads to the radioresistance of prostate cancer
International Journal of Oncology
April 12, 2018
Yong Luo et al.
solution, the tissue sections were incubated in rabbit monoclonal antibodies against BRCA1 (
1:250
,
ab16780
;
Abcam
) or Ki67 (
1:300
,
sc15402
;
Santa Cruz Biotechnology
) for 90 min, followed by
incubation
in a HRP
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Anti-BRCA1 antibody [MS110] from Abcam
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Company Info
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