Fc gamma RI/CD64 Antibody AF1257 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFc gamma RI/CD64 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF1257
NCBI Gene AliasesCD64, FCG1, FCRI, CD64A, FCGR1, IGFR1, FcgammaRI
ApplicationsWestern Blot, Blockade of Receptor-ligand Interaction
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
TargetFc gamma RI/CD64
HostGoat
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
ReactivityHuman
NCBI Full Gene NameFc gamma receptor Ia
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Fc gamma RI/CD64, Gln16-Pro288, Accession # P12314.2
ConcentrationLYOPH
PurityAntigen Affinity-purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human Fc gamma RI/CD64 in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse Fc gamma RI is observed and 10% cross-reactivity with recombinant human (rh) Fc gamma RIIA and rhFc gamma RIIIB is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) mCRP triggers angiogenesis by inducing F3 transcription and TF signalling in microvascular endothelial cellsThrombosis and HaemostasisJanuary 1, 2017Esther Peña, Raquel de de la Torre, Gemma Arderiu, Mark Slevin, Lina Badimondissociation, mECs were incubated for 1 hour with blocking antibodies against CD32 (100 µg/mL) (AF1330 and AF1257 respectively, R&D Systems). Then, cells were treated with nCRP (3 µg/mL) and incubated over a period

(2) Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subsetThe Journal of biological chemistryFebruary 20, 2015Chauhan AK, Chen C, Moore TL, DiPaolo RJ.

(3) C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expressionFEBS lettersFebruary 14, 2014Kim Y, Ryu J, Ryu MS, Lim S, Han KO, Lim IK, Han KH.

(4) Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancerPloS oneJanuary 1, 2014Forget MA, Voorhees JL, Cole SL, Dakhlallah D, Patterson IL, Gross AC, Moldovan L, Mo X, Evans R, Marsh CB, et al.

(5) Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cellsClinical and experimental immunologyFebruary 1, 2012Chauhan AK, Moore TL.

(6) C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetesDiabetologiaOctober 1, 2011Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY.

(7) C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytesJournal of leukocyte biologyOctober 1, 2008Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F.

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Fc gamma RI/CD64 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Fc gamma RI/CD64 Antibody from R&D Systems, a Bio-Techne Brand

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