Choline Kinase Alpha antibody 13520-1-AP from Proteintech Group Inc

Product Specs
ItemCholine Kinase Alpha antibody
CompanyProteintech Group Inc
Price Pricing Info Supplier Page View Company Product Page
Catalog Number13520-1-AP
ApplicationsWB, IP, IHC, IF, ELISA
IsotypeIgG
HostRabbit
ReactivityHuman, Mouse, Rat
Antibody Typeprimary antibodies
FormatPBS with 0.02% sodium azide and 50% glycerol pH 7.3
Quantity20ul
Conjugate/TagUnconjugated
ClonalityPolyclonal
PurityAntigen affinity purification
ImmunogenRecombinant Protein
NCBI Full Gene Namecholine kinase alpha
NCBI Gene AliasesCHK, CK, CKI, EK, NEDMIMS
Research AreaBinding Proteins, Metabolism, Signal transduction, Transport/Trafficking
TargetCholine Kinase Alpha
ValidationKD/KO Validated

Specifications/Features

20ul available

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Proteintech Group Inc

5500 Pearl Street, Suite 400

Rosemont,, Illinois 60018

United States

Phone: 1-888-478-4522

Email: proteintech@ptglab.com

Company Profile

Website: http://www.ptglab.com

(1) The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferationProceedings of the National Academy of Sciences of the United States of AmericaApril 11, 2023Ma Q, Jiang H, Ma L, Zhao G, Xu Q, Guo D, He N, Liu H, Meng Z, Liu J, et al.purchased from Santa Cruz Biotechnology (Shanghai, China). Rabbit antibodies that recognize human CHKα (13520-1-AP), HA (51064-2-AP), FLAG (20543-1-AP) and mouse antibodies that recognize HA tag (66006-2-Ig), FLAG (66008-4-Ig),

(2) Twist alters the breast tumor microenvironment via choline kinase to facilitate an aggressive phenotypeMolecular and cellular biochemistryApril 1, 2023Vesuna F, Penet MF, Mori N, Bhujwalla ZM, Raman V.

(3) Functional roles of FAP-α in metabolism, migration and invasion of human cancer cellsFrontiers in oncologyJanuary 1, 2023Mori N, Jin J, Krishnamachary B, Mironchik Y, Wildes F, Vesuna F, Barnett JD, Bhujwalla ZM.

(4) Altered choline level in atherosclerotic lesions: Upregulation of choline transporter-like protein 1 in human coronary unstable plaquePloS oneJanuary 1, 2023Nakamura E, Maekawa K, Saito Y, Matsumoto T, Ogawa M, Komohara Y, Asada Y, Yamashita A.

(5) Novel function of Roxadustat (FG-4592) as an anti-shock drug in sepsis by regulating mitochondrial oxidative stress and energy metabolismBiochimica et biophysica acta. General subjectsJanuary 1, 2023Long G, Pei Z, Wu M, Wei K, Du Y, Wang Q, Zhang Y, Huang S, Chen H, Xia W, et al.

(6) 1,25(OH)(2)D(3) alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathwayPlacentaDecember 1, 2022Ma Y, Yang Y, Lv M, Zhang Y, He Q, Zhang Y, Su H, Deng X, Qian Y.

(7) DHRS2 inhibits cell growth and metastasis in ovarian cancer by downregulation of CHKα to disrupt choline metabolismCell death & diseaseOctober 3, 2022Li Z, Tan Y, Li X, Quan J, Bode AM, Cao Y, Luo X.1:1000) was from Thermo Fisher Scientific (Thermo Scientific, MA, USA). The antibodies to detect CHKα (13520-1-AP, 1:500), AKT (10176-2-AP, 1:1000), and phospho-AKT (S473) (66444-1-Ig, 1:1000) were purchased from Proteintech

(8) Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cellsInternational journal of cancerMay 1, 2022Fan Z, Ma J, Pan X, Zhao L, Wu Y, Lin H, Zhao Y, Jiang H, Pan T, Li X, et al.

(9) Choline Kinase Alpha Is a Novel Transcriptional Target of the Brg1 in Hepatocyte: Implication in Liver RegenerationFrontiers in cell and developmental biologyJanuary 1, 2021Kong M, Dong W, Xu H, Fan Z, Miao X, Guo Y, Li C, Ye Q, Wang Y, Xu Y.

(10) Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 ProductionCell metabolismJune 4, 2019Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, et al.N/A p62 (WB:1/5000),ProGen,Cat#GP62-C; RRID:AB_2687531 ChoKα (WB:1/2500; IF: 1/100),Proteintech,Cat#13520–1-AP; RRID:AB_2079160 F4/80 (IF:1/100),Invitrogen,Cat#MF48000; RRID:AB_1500089 "Anti-ATP Synthase, beta chain, clone 4.3E8.D1

(11) Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesisNature communicationsJanuary 28, 2019Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Fujimoto T.Fisher 6H21L11), mouse anti-V5 (Thermo Fisher R960-25), mouse anti-choline kinase α (CKα) (Proteintech 13520-1-AP), guinea pig anti-perilipin-3 (Progen GP30), and mouse anti-nucleopore complex (Covance MMS-120P) antibodies

(12) Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured miceLipids in health and diseaseAugust 14, 2017Ming YN, Zhang JY, Wang XL, Li CM, Ma SC, Wang ZY, Liu XL, Li XB, Mao YM.

(13) Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer TreatmentClinical cancer research : an official journal of the American Association for Cancer ResearchJuly 15, 2017Saxena R, Yang C, Rao M, Turaga RC, Garlapati C, Gundala SR, Myers K, Ghareeb A, Bhattarai S, Kamalinia G, et al.

(14) Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopyPloS oneJanuary 1, 2017Kim HS, Tian L, Kim H, Moon WK.

(15) The Tumor Microenvironment Modulates Choline and Lipid MetabolismFrontiers in oncologyJanuary 1, 2016Mori N, Wildes F, Takagi T, Glunde K, Bhujwalla ZM.

(16) Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survivalNMR in biomedicineDecember 1, 2015Mori N, Wildes F, Kakkad S, Jacob D, Solaiyappan M, Glunde K, Bhujwalla ZM.

(17) Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesisMolecular biology of the cellAugust 15, 2015Aitchison AJ, Arsenault DJ, Ridgway ND.

(18) Choline kinase inhibition in rheumatoid arthritisAnnals of the rheumatic diseasesJuly 1, 2015Guma M, Sanchez-Lopez E, Lodi A, Garcia-Carbonell R, Tiziani S, Karin M, Lacal JC, Firestein GS.

(19) Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer CellsPloS oneJanuary 1, 2015Kim HS, Tian L, Jung M, Choi SK, Sun Y, Kim H, Moon WK.

(20) ras-Induced up-regulation of CTP:phosphocholine cytidylyltransferase α contributes to malignant transformation of intestinal epithelial cellsThe Journal of biological chemistryJanuary 4, 2013Arsenault DJ, Yoo BH, Rosen KV, Ridgway ND.

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Choline Kinase Alpha antibody

Choline Kinase Alpha antibody

Choline Kinase Alpha antibody from Proteintech Group Inc

Description

Specifications/Features

Proteintech Group Inc

Citations (20)

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Choline Kinase Alpha antibody from Proteintech Group Inc

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