Phospho-PLCgamma1 (Tyr783) Antibody 2821L from Cell Signaling Technology

Product Specs
ItemPhospho-PLCgamma1 (Tyr783) Antibody
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number2821L
Quantity300 µl
ApplicationsW
ReactivityH, M, R
TargetPLCg1 (Tyr783) phosphate
ModificationsPLCg1 (Tyr783) phosphate
HostRabbit
NCBI Gene AliasesNCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
NCBI Full Gene Namephospholipase C gamma 1
ClonalityPolyclonal
Research AreaCa, cAMP and Lipid Signaling
Molecular Weight155

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Corneal Vascularization Associated With a Novel PDGFRB VariantInvestigative Opthalmology & Visual ScienceNovember 7, 2023Titas Gladkauskas, Ove Bruland, Leen Abu Safieh, Deepak P. Edward, Eyvind Rødahl, Cecilie Bredrup(catalogue numbers in parentheses): phospho-Tyr70-STAT1 (#7649), STAT1 (#9172), phospho-Tyr783-PLCγ1 (#2821), PLCγ1 (#5690), phospho-Ser473-AKT (#4060), phospho-AKTThr308 (#4056), AKT (#4691), phospho-38 MAPK

(2) Treating solid tumors with TCR-based chimeric antigen receptor targeting extra domain B-containing fibronectinJournal for ImmunoTherapy of CancerAugust 16, 2023Zhijie Zhang, Chang Liu, Muhan Wang, Rongcheng Sun, Zhe Yang, Zhen Hua, Yushuang Wu, Mengting Wu, Hang Wang, Wen Qiu, et al.Cell Signaling Technology), anti-pLCK-Y394 (AP0182, ABclonal), anti-PLCγ (2822, Cell Signaling Technology), anti-pPLCγ (2821, Cell Signaling Technology), anti-NFATc1 (5861, Cell Signaling Technology), anti-NF-κB p65 (6956, Cell Signaling Technology

(3) PDE4DIP contributes to colorectal cancer growth and chemoresistance through modulation of the NF1/RAS signaling axisCell Death & DiseaseJune 24, 2023Rulu Pan, Juji Dai, Weicheng Liang, Hongxiao Wang, Lin Ye, Siqi Ye, Ziqi Lin, Shishun Huang, Yan Xiong, Li Zhang, et al.(#2276), PCNA (#13110), phospho-MARCKS (#11992), MARCKS (#5607), phospho-PKC (pan) (#2060), phospho-PLCγ (#2821), phospho-PKA (#4781), PKA (#4782), phospho-CREB (#9198), CREB (#9197), GM130 (#12480), IgG-rabbit (#2729),

(4) Structural basis for FGF hormone signallingNatureJune 1, 2023Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, et al.phosphorylated FRS2α (1:1000, no. 3864S, Cell Signaling Technology), phosphorylated PLCγ1 (1:1000, no. 2821S, Cell Signaling Technology), phosphorylated ERK1/2 (1:1000, no. 4370S, Cell Signaling Technology), α-tubulin

(5) The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial functionJournal of cell scienceMay 15, 2023Critchley WR, Smith GA, Zachary IC, Harrison MA, Ponnambalam S.phosphorylated Akt (1:1000 for IB, 4060B), PLCγ1 (1:1000 for IB, #5690), phosphorylated PLCγ1 (1:1000 for IB, #2821), ERK1/2 (1:1000 for IB, #4695) and phosphorylated ERK1/2 (1:1000 for IB, #4370) from Cell Signalling

(6) Activin A Limits VEGF-Induced Permeability via VE-PTPInternational journal of molecular sciencesMay 12, 2023Baccouche B, Lietuvninkas L, Kazlauskas A.CulturewareTM (Applied BioPhysics, Inc., Troy, NY, USA). Anti–Enos Ser1177 (9571), Anti-PLC Tyr783 (2821), Anti-VEGFR2 (247), and Anti-P-VEGFR2 1175 (2478) were purchased from Cell Signaling, Inc. (Danvers,

(7) The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβInternational Journal of Molecular SciencesApril 24, 2023Niki Sarri, Natalia Papadopoulos, Johan Lennartsson, Carl-Henrik Heldinphosphorylated p44/p42 Erk1/2 MAPK (pThr202/pThr204, #9101), PLCγ1 (#2822), phosphorylated PLCγ1 (pTyr783, #2821), STAT3 (79D7, #4904), phosphorylated STAT3 (pTyr705, D3A7, #9145) and LC3B (#3868) were purchased from

(8) Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasisJournal of cell communication and signalingMarch 1, 2023Xing L, Huang G, Chen R, Huang L, Liu J, Ren X, Wang S, Kuang H, Kumar A, Kim JK, et al.(44-1047G, Invitrogen), pTyr1214-VEGFR2 (AF1766, R&D Systems), VEGFR2 (9698, Cell Signaling), pTyr783-PLCγ1 (2821S, Cell Signaling), PLCγ1 (5690S, Cell Signaling), pSer1177-eNOS (9570, Cell Signaling), and eNOS (32027,

(9) Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBNCellsFebruary 1, 2023Hyeun-Wook Chang, Kyeong-Hwa Sim, Youn-Ju Lee(#9102), p-IKK (#2697), p-JNK (#9251), JNK (#9258), p-p38 MAPK (#9215), p38 MAPK (#9212), p-PLCγ1 (#2821), and GAPDH (#2118) were purchased from Cell Signaling Technology (Danvers, MA). Antibodies against

(10) c-Abl Tyrosine Kinase Is Required for BDNF-Induced Dendritic Branching and GrowthInternational Journal of Molecular SciencesJanuary 18, 2023América Chandía-Cristi, Nicolás Stuardo, Cristian Trejos, Nancy Leal, Daniela Urrutia, Francisca C. Bronfman, Alejandra Álvarez Rojasanti-PLC-γ (Cell Signaling, Danvers, MA, USA; #cat 2822), anti-phospho-PLC-γ (Tyr 783) (Cell Signaling, #cat 2821), anti-AKT (Cell Signaling, #cat 9272), anti-phospho-AKT (Ser 473) (Cell Signaling, #cat 9291), anti-ERK

(11) Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosisJournal of Experimental MedicineJanuary 2, 2023Masato Ogishi, Rui Yang, Rémy Rodriguez, Dominic P. Golec, Emmanuel Martin, Quentin Philippot, Jonathan Bohlen, Simon J. Pelham, Andrés Augusto Arias, Taushif Khan, et al.Clone: E4X7M, 1:1,000, 4 °C overnight), anti-phospho-PLCγ1 (Y783) rabbit polyclonal antibody (Cat: 2821, 1:1,000; Cell Signaling Technology, 4 °C overnight), HRP-conjugated anti-DDK mAb (Cat: 637311, Clone:

(12) Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discriminationNature immunologySeptember 1, 2022Voisinne G, Locard-Paulet M, Froment C, Maturin E, Menoita MG, Girard L, Mellado V, Burlet-Schiltz O, Malissen B, Gonzalez de Peredo A, et al.(Cell Signaling Technology, catalog no. 2855, clone 234B4), anti-PLCγ1-pY783 (Cell Signaling Technology, catalog no. 2821), anti-PLCγ1 (Cell Signaling Technology, catalog no. 2822), anti-LAT-pY220 (Cell Signaling Technology,

(13) Effects of 1α,25-dihydroxyvitamin D3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cellsBiochemistry and Biophysics ReportsSeptember 1, 2022Frida Olsson, Niki Sarri, Natalia Papadopoulos, Johan Lennartsson, Maria Norlinover-night with primary antibodies. The following primary antibodies were used: rabbit anti-pY783-PLCγ1 (#2821, 1:1000, Cell Signaling Technology), mouse anti-PLCγ1 (H00005335-M01, 1:1000, Novus Biologicals), mouse

(14) A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR SignalingCellsSeptember 1, 2022Annika Schultz, Marvin Schnurra, Ali El-Bizri, Nadine M. Woessner, Sara Hartmann, Roland Hartig, Susana Minguet, Burkhart Schraven, Luca Simeoni"Merck Millipore, upstate" Lck,3A5,Santa Cruz Biotechnology Lck pY505,2751S,Cell Signaling Technology PLCγ pY783,2821S,Cell Signaling Technology p44/42 MAPK (Erk1/2) (pT202/pY204),D13.14.4E,Cell Signaling Technology Src

(15) Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrinCancer Gene TherapyJuly 1, 2022Marco Rusnati et al.by western blot for the phosphorylated form of VEGFR2, ERK1/2 (#4370, Cell Signalling), or PLC-γ (#2821, Cell Signalling). For FGFR1 phosphorylation assay, cells were treated as above with FGF2 at 30 ng/ml. VEGFR2

(16) The hexosamine pathway and coat complex II promote malignant adaptation to nutrient scarcityLife science allianceJuly 1, 2022Dragic H, Barthelaix A, Duret C, Le Goupil S, Laprade H, Martin S, Brugière S, Couté Y, Machon C, Guitton J, et al.Tyr1148 (4404; 1:1,000), p-Shc Tyr239/240 (2434; 1:1,000), p-Gab1 Tyr627 (3233; 1:1,000), p-PLCg1 Tyr783 (2821; 1:1,000), p-ERK (4370; 1:1,000), β-Tubulin (2146; 1:1,000), actin (8432; 1/1,000), PD-L1 (13684; 1:1,000),

(17) Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor EffectsBiomolecules & TherapeuticsJuly 1, 2022Hyo Jeong Lee, Yeongyu Moon, Jungil Choi, Jeong Doo Heo, Sekwang Kim, Hari Krishna Nallapaneni, Young-Won Chin, Jongkook Lee, Sun-Young Hanphospho-Akt (Ser473; #9271; 1:1000), phospho-p44/42 MAPK (ERK1/2; #4370; 1:1000), phospho-PLCγ1 (Tyr783; #2821; 1:1000), PARP (#9542; 1:1000), and LC3A/B (D3U4C; #12741; 1:1000) were purchased from Cell Signaling Technology

(18) NK Cells Equipped With a Chimeric Antigen Receptor That Overcomes Inhibition by HLA Class I for Adoptive Transfer of CAR-NK CellsFrontiers in ImmunologyMay 2, 2022Xiaoxuan Zhuang, Eric O. Longanalyzing by western blot using phospho-Erk1/2 (Cell Signaling #9101) and phospho-PLCγ1 (Cell Signaling #2821) antibodies. Data Sharing Statement All supporting data are available on request. Results Synergistic

(19) NAD⁺-boosting molecules suppress mast cell degranulation and anaphylactic responses in miceTheranosticsApril 11, 2022Hyun-Woo Kim, Ga-Hee Ryoo, Hyun-Young Jang, So-Young Rah, Dong Hyun Lee, Do-Kyun Kim, Eun Ju Bae, Byung-Hyun ParkAbcam), LAT (sc-53550, Santa Cruz Biotechnology), Sirt6 (#12486), p-Syk (#2717), Syk (#13198), p-PLCγ (#2821), p-PI3K (#4228), PI3K (#4257), p-Akt (#9271), Akt (#9272), p-ERK (#4370), ERK (#9102), p-p38 (#9211),

(20) FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse modelThe Journal of experimental medicineApril 4, 2022Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, et al.number 9411; 1:1,000 dilution; Cell Signaling), a polyclonal anti-phospho-PLCγ1 antibody (catalog number 2821; 1:1,000 dilution; Cell Signaling), a polyclonal anti-PLCγ1 antibody (catalog number 2822; 1:1,000 dilution;

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(1)

6/23/2020Good Antibody for Phospho-PLCgamma1 from CST Hong SunMight need to titrate before use.
(1)

8/14/2015Good Phospho-PLC-gamma-1 Antibody Raj KumarIn present experiment, equal amount of proteins from growth factor treated cells were resolved in 7.5% SDS-PAGE. Western transfer was done in nitrocellulose membrane and immunodetection was done for ... Read Review

Phospho-PLCgamma1 (Tyr783) Antibody

Phospho-PLCgamma1 (Tyr783) Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PLCgamma1 (Tyr783) Antibody from Cell Signaling Technology

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