Fig 1: The percentage of Fos-HCRT immunopositive neurons in the lateral hypothalamic area (LHA) (A), total intake of all compounds (B), and correlation analysis between the individual sucrose solution preference and its intake from total intake of all compounds as well as between the individual sucrose solution preferences from total intake of all compounds and percentage of Fos-HCRT neurons in LHA (C) during the 60 min-lasting sweet solution test in the overnight fasted male Shank3b genotype mice prenatally exposed to gut microbiota from neurotypical control children (CTRL) and from children with autism spectrum disorder (ASD), mean ± SEM. The arrow indicates a statistically significant difference from the respective group (p < 0.05). r 0.36 to 0.67 indicates a moderate correlation, r 0.68 to 0.89 a strong correlation, and r > 0.90 a very strong correlation. NS—not significant.