CD4 Antibody eFluor 450 48-0049-42 from Thermo Fisher Scientific

Product Specs
ItemCD4 Antibody eFluor 450
CompanyThermo Fisher Scientific
Price Pricing Info Supplier Page View Company Product Page
Catalog Number48-0049-42
Quantity100 Tests
ApplicationsFlow Cytometry
Concentration5 µL/Test
Conjugate/TageFluor™ 450
FormatPBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
ReactivityHuman
TargetCD4
IsotypeIgG1 kappa
CloneRPA-T4
HostMouse
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C, store in dark, DO NOT FREEZE!
Antibody TypePrimary
Storage4° C, store in dark, DO NOT FREEZE!

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) Post-transplant cyclophosphamide prevents xenogeneic graft-versus-host disease while depleting proliferating regulatory T cellsiScienceMarch 17, 2023Ritacco C, Köse MC, Courtois J, Canti L, Beguin C, Dubois S, Vandenhove B, Servais S, Caers J, Beguin Y, et al.(RPA-T4), eFluor™ 450",Thermo Fisher Scientific,Thermo Fisher Scientific,Thermo Fisher Scientific,Cat#48-0049-42; RRID:AB_1272057 PE/Cyanine7 anti-human CD8 Antibody,BioLegend,BioLegend,BioLegend,Cat#344712; RRID:AB_2044008 APC-Cy™7 Mouse Anti-Human CD8

(2) Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunityNature communicationsDecember 10, 2022McEvoy CM, Murphy JM, Zhang L, Clotet-Freixas S, Mathews JA, An J, Karimzadeh M, Pouyabahar D, Su S, Zaslaver O, et al.

(3) The CD4+ T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn’s diseaseImmunityOctober 1, 2022Thomas K. Pedersen, Eric M. Brown, Damian R. Plichta, Joachim Johansen, Shaina W. Twardus, Toni M. Delorey, Helena Lau, Hera Vlamakis, James J. Moon, Ramnik J. Xavier, et al.anti-CD3-PE-Cy7 (ThermoFischer Scientific cat.no 25-0038-42), anti-CD4-eFluor450 (eBioscienceTM cat. no. 48-0049-42), anti-CD8-PE (Biolegend cat. no. 344706), anti-CD19-FITC (Biolegend cat. no. 392508) and anti-CD14-APC

(4) Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 ReceptorCellsAugust 19, 2022Rode AKO, Buus TB, Mraz V, Al-Jaberi FAH, Lopez DV, Ford SL, Hennen S, Eliasen IP, Klewe IV, Gharehdaghi L, et al.

(5) Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seqCell discoveryMay 10, 2022Wang B, Wang C, Wan Y, Gao J, Ma Y, Zhang Y, Tong J, Zhang Y, Liu J, Chang L, et al.

(6) Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenariansFrontiers in immunologyJanuary 1, 2022Zhong J, Ding R, Jiang H, Li L, Wan J, Feng X, Chen M, Peng L, Li X, Lin J, et al.

(7) Single-Cell Transcriptomic Analysis of Peripheral Blood Reveals a Novel B-Cell Subset in Renal Allograft Recipients With AccommodationFrontiers in PharmacologySeptember 30, 2021Quan Zhuang, Hao Li, Bo Peng, Yang Liu, Ying Zhang, Haozheng Cai, Shu Liu, Yingzi Ming700 (eBioscience, Catalog Number: 56-0038-42), Anti-Hu CD4-eFluor 450 (eBioscience, Catalog Number: 48-0049-42), anti-Hu CD14-APC/cyanine7 (BioLegend, Catalog Number: 325620), anti-Hu CD19-PerCP-Cyanine5.5 (Invitrogen,

(8) Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell ActivationCancersApril 13, 2021Prat M, Salon M, Allain T, Dubreuil O, Noël G, Preisser L, Jean B, Cassard L, Lemée F, Tabah-Fish I, et al.

(9) Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 CellsBiomolecules & therapeuticsMarch 1, 2021Yoon H, Sung JH, Song MJ.

(10) An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell DevelopmentImmunityDecember 15, 2020Chopp LB, Gopalan V, Ciucci T, Ruchinskas A, Rae Z, Lagarde M, Gao Y, Li C, Bosticardo M, Pala F, et al.RPA-T4),Thermofisher,"Cat# 17-0049-42, RRID:AB_1272048" Anti-CD4-eFluor 450 (Clone RPA-T4),Thermofisher,"Cat# 48-0049-42, RRID:AB_1272057" Anti-CD69-FITC (Clone FN50),BD Pharmigen,"Cat# 560969, RRID:AB_10562195" Anti-CD8-PerCp-Cy5.5

(11) Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapyCancer immunology, immunotherapy : CIIMarch 1, 2020Thomas R, Shaath H, Naik A, Toor SM, Elkord E, Decock J.

(12) Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer CellsFrontiers in immunologyJanuary 1, 2020Møller SH, Mellergaard M, Madsen M, Bermejo AV, Jepsen SD, Hansen MH, Høgh RI, Aldana BI, Desler C, Rasmussen LJ, et al.

(13) HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune MicroenvironmentJournal of CancerJanuary 1, 2020Kim YD, Park SM, Ha HC, Lee AR, Won H, Cha H, Cho S, Cho JM.

(14) MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligoMolecular medicine reportsOctober 1, 2019Lv M, Li Z, Liu J, Lin F, Zhang Q, Li Z, Wang Y, Wang K, Xu Y.

(15) Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor TargetingCancer cellMarch 18, 2019Srivastava S, Salter AI, Liggitt D, Yechan-Gunja S, Sarvothama M, Cooper K, Smythe KS, Dudakov JA, Pierce RH, Rader C, et al.APC/Cy7,BioLegend,"Cat# 368515, RRID:AB_2566375" Anti-human CD4 eFluor 450,Thermo Fisher Scientific,"Cat# 48–0049-42, RRID:AB_1272057" Anti-human Tim-3 PE,BioLegend,"Cat# 345005, RRID:AB_1877236" Anti-human CD8 eFluor

(16) RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody ResponsesCellOctober 4, 2018Bradley T, Peppa D, Pedroza-Pacheco I, Li D, Cain DW, Henao R, Venkat V, Hora B, Chen Y, Vandergrift NA, et al.

(17) The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with AtherosclerosisActa Cardiologica SinicaSeptember 1, 2018Ding JW, Zhou T, Zheng XX, Wang XA, Tong XH, Luo CY, Zhang ZQ, Yu B.

(18) Preliminary investigation on the abnormal mechanism of CD4+FOXP3+CD25high regulatory T cells in pediatric B‑cell acute lymphoblastic leukemiaExperimental and Therapeutic MedicineJune 19, 2018Si‑Xi Liu, Hai‑Rong Xiao, Guo‑Bing Wang, Xiao‑Wen Chen, Chang‑Gang Li, Hui‑Rong Mai, Xiu‑Li Yuan, Guo‑Sheng Liu, Fei‑Qiu WenIL‑2Rα on CD4+T, peripheral blood samples were stained and gated with CD4‑eFlour450 (2.5 µg/ml; cat. no. 48‑0049‑42; Invitrogen; Thermo Fisher Scientific, Inc.) for 30 min at 4˚C, fixed and permeabilized with intracellular

(19) Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In VivoCellAugust 10, 2017Horwitz JA, Bar-On Y, Lu CL, Fera D, Lockhart AAK, Lorenzi JCC, Nogueira L, Golijanin J, Scheid JF, Seaman MS, et al.

(20) CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancerJCI insightJune 2, 2017Gu-Trantien C, Migliori E, Buisseret L, de Wind A, Brohée S, Garaud S, Noël G, Dang Chi VL, Lodewyckx JN, Naveaux C, et al.

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(1)

10/19/2017Excellent Antibody For Human CD4 Staining Prabhakaran KumarI used this antibody to analyze CD4/CD8 phenotype of human thymus. This antibody worked well and gave a nice distinct population.

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CD4 Antibody eFluor 450 from Thermo Fisher Scientific

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CD4 Antibody eFluor 450 from Thermo Fisher Scientific

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