Fig 1: Effects of hyperforin in ?d T cells on IMQ-induced psoriasis-like skin inflammation. Tcrd –/– mice were transferred with PBS or naive ?d T cells pretreated with hyperforin (?d-Hyperforin) or not (?d-Vehicle). The mice were then subjected to IMQ-induced psoriasis as part of the psoriasis-like mouse model. The back-skin photos of mice (A) and H&E staining of skin lesions (B) (scale bars: 100 µm), and PASI scores (C). n = 3. (D, F) Detection of the transferred ?d T cells in skin. (E, G) Percentage of IL-17A+ cells in dermal ?d T cells (gated on CD3+ ?dTCR+ T cells). n = 3. Data are presented as the mean ± SD. (**P < 0.01).