Integrin alpha-M antibody orb348856 from Biorbyt

Product Specs
ItemIntegrin alpha-M antibody
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb348856
Quantity0.2 mg
ApplicationsELISA, FC
Conjugate/TagUnconjugated
PurityPurified
ReactivityHuman
TargetIntegrin α-M
IsotypeIgG1
Clone107
ImmunogenWild type (WT) recombinant CD11b
ClonalityMonoclonal
HostMouse
NCBI Full Gene Nameintegrin subunit alpha M
NCBI Gene AliasesCD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
StorageStore at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C
Concentration1 mg/ml

Specifications/Features

Application Notes: The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.

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