Anti-GABA(A) gamma2 Receptor (extracellular) Antibody AGA-005 from Alomone Labs, Ltd.

Product Specs
ItemAnti-GABA(A) gamma2 Receptor (extracellular) Antibody
CompanyAlomone Labs, Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAGA-005
Domain/Region/Terminusextracellular
Brand/TrademarkAlomone Labs Ltd
ApplicationsICC, IF, IHC, LCI, WB
FormatReconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3., Lyophilized Powder
HostRabbit
Conjugate/TagUnconjugated
ClonalityPolyclonal
ReactivityHuman (Tested);Mouse (Tested);Rat (Tested)
Quantity1 X 50 mcl, 1 X 0.2 ml, 1 X 25 mcl
Antibody TypePrimary
Concentration08 mg/ml
PurityAffinity purified on immobilized antigen
IsotypeIgG
ImmunogenSynthetic peptide
Research AreaEpilepsy, Neuroscience, Auditory, Auditory System, Hearing, Sensory System, Cancer, tumor, tumour, Neurological Diseases, Addiction, Reward, Depression
Gene NameGABRG2
ValidationAs per applications, See images, contact for clarifications
NCBI Full Gene Namegamma-aminobutyric acid type A receptor subunit gamma 2
pH RangepH 7.4

Specifications/Features

starting price for North American orders, for exact pricing view product page

Sequence

QKSDDDYEDYASNKT(C), corresponding to amino acid residues 39-53 of rat GABA(A) γ2 receptor

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Alomone Labs, Ltd.

PO Box 4287

Jerusalem 91042

Israel

Phone: +972-2-587-2202
+972-2-587-1101

Company Profile

Website: http://www.alomone.com/

(1) Altered GABAA Receptor Expression in the Primary Somatosensory Cortex of a Mouse Model of Genetic Absence EpilepsyInternational Journal of Molecular SciencesDecember 10, 2022Muhammad Hassan, Nadia K. Adotevi, Beulah Leitchab8340, Abcam, Cambridge, UK), GABAAR β3 (1:1000; ab4046, Abcam, Cambridge, UK), GABAAR γ2 (1:200; AGA-005, Alomone, Jerusalem, Israel), and GABAAR δ (1:200; AGA-014, Alomone, Jerusalem, Israel) with β-actin

(2) Nogo-A Modulates the Synaptic Excitation of Hippocampal Neurons in a Ca²⁺-Dependent MannerCellsSeptember 3, 2021Metzdorf K, Fricke S, Balia MT, Korte M, Zagrebelsky M.assess their surface localization. The anti-GABAA receptor antibody anti-GABAAR γ2 (Alomone Labs, Cat# AGA-005, 1:500) was added 20 min before the 10-min antibody treatment. In the case of the AMPA receptors, the

(3) Physiological role for GABA(A) receptor desensitization in the induction of long-term potentiation at inhibitory synapsesNature communicationsApril 9, 2021Field M, Dorovykh V, Thomas P, Smart TG.Tween20, pH 2.2), and subsequently re-probed for total γ2 GABAAR subunit levels (anti-γ2: Alomone, 1:500, AGA-005). Analysis was carried out using GelAnalyser 2010a (ver 19.1). Lanes and bands were detected automatically,

(4) A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiationNature communicationsSeptember 28, 2018Letellier M, Szíber Z, Chamma I, Saphy C, Papasideri I, Tessier B, Sainlos M, Czöndör K, Thoumine O.(Agrobio, clone G02141, 0.2 mg ml−1, 1:100 dilution in culture medium) or rabbit anti-γ2 antibody (Alomone, AGA-005, 1:100) respectively. This was followed by fixation, membrane permeabilization and BSA blocking. Cultures

(5) Anxiolytic effect of CPEB1 knockdown on the amygdala of a mouse model of inflammatory painBrain research bulletinMarch 1, 2018Yue J, Wang XS, Guo YY, Zheng KY, Liu HY, Hu LN, Zhao MG, Liu SB.

(6) Antisecretory Factor Modulates GABA_A Receptor Activity in NeuronsJournal of molecular neuroscience : MNFebruary 1, 2018Bazzurro V, Gatta E, Cupello A, Lange S, Robello M.

(7) SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABA(A) Receptor γ2 SubunitFrontiers in molecular neuroscienceJanuary 1, 2018Durisic N, Keramidas A, Dixon CL, Lynch JW.

(8) Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral IschemiaOxidative medicine and cellular longevityJanuary 1, 2018Wang Y, Jiang SW, Liu X, Niu L, Ge XL, Zhang JC, Wang HR, Fei AH, Gao CJ, Pan SM.

(9) Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cordThe Journal of cell biologySeptember 4, 2017Cantaut-Belarif Y, Antri M, Pizzarelli R, Colasse S, Vaccari I, Soares S, Renner M, Dallel R, Triller A, Bessis A.

(10) Inter-Synaptic Lateral Diffusion of GABAA Receptors Shapes Inhibitory Synaptic CurrentsNeuronJuly 5, 2017de Luca E, Ravasenga T, Petrini EM, Polenghi A, Nieus T, Guazzi S, Barberis A.polyclonal anti-GABAARα1,Alomone,"AGA-001, RRID: AB_2039862" Rabbit polyclonal anti-GABAARγ2,Alomone,AGA-005; RRID: AB_2039870 Rat monoclonal anti-HA,Roche,"1186742300, RRID: AB_10094468" Anti vGAT-oyster 550,SynapticSystems,"131103C3,

(11) Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s DiseaseFrontiers in Molecular NeuroscienceJune 20, 2017Zhuowei Du, Margot Tertrais, Gilles Courtand, Thierry Leste-Lasserre, Laura Cardoit, Frédérique Masmejean, Christophe Halgand, Yoon H. Cho, Maurice Garret2015) 1:1000 WB GABAA R β3 NeuroMab (Du et al., 2016) N87/25 1:1000 WB GABAA R γ2 (Gurba et al., 2012) Alomone AGA-005 1:300 WB (Vlachos et al., 2013) GABAAR δ Millipore AB9752 1:1000 WB (Sarkar et al., 2011) Vgat Synaptic Systems

(12) De novo GABRG2 mutations associated with epileptic encephalopathiesBrain : a journal of neurologyJanuary 1, 2017Shen D, Hernandez CC, Shen W, Hu N, Poduri A, Shiedley B, Rotenberg A, Datta AN, Leiz S, Patzer S, et al.

(13) Differential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneityScientific reportsOctober 20, 2016Wang J, Shen D, Xia G, Shen W, Macdonald RL, Xu D, Kang JQ.

(14) Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's diseaseNeuroscienceAugust 4, 2016Du Z, Chazalon M, Bestaven E, Leste-Lasserre T, Baufreton J, Cazalets JR, Cho YH, Garret M.

(15) Differential molecular and behavioural alterations in mouse models of GABRG2 haploinsufficiency versus dominant negative mutations associated with human epilepsyHuman molecular geneticsAugust 1, 2016Warner TA, Shen W, Huang X, Liu Z, Macdonald RL, Kang JQ.

(16) Selective chemical genetic inhibition of protein kinase C epsilon reduces ethanol consumption in miceNeuropharmacologyAugust 1, 2016Maiya R, McMahon T, Wang D, Kanter B, Gandhi D, Chapman HL, Miller J, Messing RO.

(17) Differential vesicular sorting of AMPA and GABAA receptorsProceedings of the National Academy of Sciences of the United States of AmericaFebruary 16, 2016Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL.

(18) Benzodiazepine ligands rapidly influence GABAA receptor diffusion and clustering at hippocampal inhibitory synapsesNeuropharmacologyJanuary 1, 2015Lévi S, Le Roux N, Eugène E, Poncer JC.

(19) Co-expression of γ2 subunits hinders processing of N-linked glycans attached to the N104 glycosylation sites of GABAA receptor β2 subunitsNeurochemical researchJune 1, 2014Lo WY, Lagrange AH, Hernandez CC, Gurba KN, Macdonald RL.

(20) Homeostatic regulation of gephyrin scaffolds and synaptic strength at mature hippocampal GABAergic postsynapsesCerebral cortex (New York, N.Y. : 1991)November 1, 2013Vlachos A, Reddy-Alla S, Papadopoulos T, Deller T, Betz H.

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