Anti-Cav2.3 (CACNA1E) Antibody ACC-006 from Alomone Labs, Ltd.

Product Specs
ItemAnti-Cav2.3 (CACNA1E) Antibody
CompanyAlomone Labs, Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberACC-006
Brand/TrademarkAlomone Labs Ltd
ClonalityPolyclonal
ApplicationsICC, IF, IHC, WB
HostRabbit
FormatLyophilized Powder, Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 5% sucrose, 0.025% NaN3
Quantity1 X 25 mcl, 1 X 50 mcl, 1 X 0.2 ml
Conjugate/TagUnconjugated
ReactivityHuman (Tested);Mouse (Tested);Rat (Tested)
Antibody TypePrimary
Concentration03 mg/ml
PurityAffinity purified on immobilized antigen
IsotypeIgG
ImmunogenSynthetic peptide
Domain/Region/TerminusIntracellular loop between domains II and III
Research AreaDiabetes, Metabolic diseases, Pain, Nociception, Touch, Somatosensory, Neuroscience,Visual, Sensory System, Cancer, tumor, tumour, Neurological Diseases, Depression, migraine, T-cells, t cells, t lymphocytes, immunology, immunity, immune cells
Gene NameCACNA1E
TargetCaV2.3 (CACNA1E) Channel
ValidationAs per applications, See images, contact for clarifications
pH RangepH 7.4

Specifications/Features

starting price for North American orders, for exact pricing view product page

Sequence

(C)SASQERSLDEGVSIDG, corresponding to amino acid residues 892-907 of rat CaV2.3

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Alomone Labs, Ltd.

PO Box 4287

Jerusalem 91042

Israel

Phone: +972-2-587-2202
+972-2-587-1101

Company Profile

Website: http://www.alomone.com/

(1) Single-Cell RNA-Seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E DeficiencySSRN Electronic JournalApril 1, 2022Carrie Finno, Janel Peterson, Mincheol Kang, Seojin Park, Matthew H. Bordbari, Blythe Durbin-Johnson, Matthew Settles, Maria C. Perez-Flores, Jeong H. Lee, Ebenezer N. Yamoahanti KCNV1 (Abcam, #ab175548), mouse anti KCNMB2 (Abcam, #ab94598), rabbit anti Cav2.3 (Alomone Labs, #ACC-006), mouse anti tyrosine hydroxylase (TH; LSBio, #LS-C338121), rabbit anti TH (LSBio, #LS-C354112), rabbit

(2) GABA_B receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminalseLifeApril 29, 2021Bhandari P, Vandael D, Fernández-Fernández D, Fritzius T, Kleindienst D, Önal C, Montanaro J, Gassmann M, Jonas P, Kulik A, et al.by rotating for 16 hr at 4°C in the presence of 2.5 μl of 0.3 μg/μl anti-Cav2.3 (CACNA1E) antibody (ACC-006, Alomone Labs, Jerusalem, Israel). The next day, 10 μl (dry volume) of a 1:1 mixture of protein-A and

(3) How to Make Immunotherapy an Effective Therapeutic Choice for Uveal MelanomaCancersApril 23, 2021Marseglia M, Amaro A, Solari N, Gangemi R, Croce E, Tanda ET, Spagnolo F, Filaci G, Pfeffer U, Croce M.

(4) An ancestral MAGUK protein supports the modulation of mammalian voltage-gated Ca(2+) channels through a conserved Ca(V)β-like interfaceBiochimica et biophysica acta. BiomembranesNovember 1, 2020Segura E, Mehta A, Marsolais M, Quan XR, Zhao J, Sauvé R, Spafford JD, Parent L.

(5) Sleep deprivation of rats increases postsurgical expression and activity of L-type calcium channel in the dorsal root ganglion and slows recovery from postsurgical painActa neuropathologica communicationsDecember 23, 2019Li Q, Zhu ZY, Lu J, Chao YC, Zhou XX, Huang Y, Chen XM, Su DS, Yu WF, Gu XY.anti-Cav2.2 antibody (N-type; 1:200, ACC-002, Alomone), rabbit anti-Cav2.3 antibody (R-type; 1:200, ACC-006, Alomone), rabbit anti-Cav3.2 antibody (T-type; 1:200, ACC-001, Alomone), mouse anti-Egr1 antibody(1:200,

(6) Phosphorylated CRMP2 Regulates Spinal Nociceptive NeurotransmissionMolecular neurobiologyJuly 1, 2019Yu J, Moutal A, Dorame A, Bellampalli SS, Chefdeville A, Kanazawa I, Pham NYN, Park KD, Weimer JM, Khanna R.scientific, San Diego, CA PSD95 Mouse MA1–045 Thermofisher scientific, San Diego, CA CaV2.3 Rabbit ACC-006 Alomone, Jerusalem, Israel CB1R Rabbit abl37410 Abeam, Cambridge, UK Actin Rabbit A2066 Sigma,

(7) Calcium Channel Ca_V2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin NeuronsCell reportsOctober 9, 2018Smith MA, Katsouri L, Virtue S, Choudhury AI, Vidal-Puig A, Ashford MLJ, Withers DJ.SDS-PAGE gels, transferred to nitrocellulose membranes and blotted with antibodies against CaV2.3 (1:1000, #ACC-006 Alomone Labs) and Na+/K+-ATPase α-1 (1:1000, #05-369 Millipore). Detection was performed using enhanced

(8) Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetesPloS oneJanuary 1, 2018Bhandage AK, Jin Z, Korol SV, Tafreshiha AS, Gohel P, Hellgren C, Espes D, Carlsson PO, Sundström-Poromaa I, Birnir B.Alomone labs, Cat No. ACC-061), CaV1.3 (1:500, Alomone labs, Cat No. ACC-005), CaV2.3 (1:500, Alomone labs, Cat No. ACC-006) and GAPDH (1:3000; Merck Millipore, Cat No. ABS16). After intensive washing with TBS-T, the membranes

(9) miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channelsPainSeptember 1, 2017Gandla J, Lomada SK, Lu J, Kuner R, Bali KK.Guinea pig anti-HCN1 (1:100, Alomone Labs, AGP203) rabbit anti-Cav2.3 antibody (1:80, Alomone Labs, ACC-006), Biotinylated-Isolectin B4 (1:100; B-1205, Vector, Burlingame, CA), Guinea pig Substance P (1:150;

(10) R-Type Ca²⁺channels couple to inhibitory neurotransmission to the longitudinal muscle in the guinea-pig ileumExperimental PhysiologyMarch 1, 2017Eileen S. Rodriguez-Tapia, Vinogran Naidoo, Matthew DeVries, Alberto Perez-Medina, James J. Galligan(final dilution = 1.5 μg/ml) was used to localize CaV2.3 (Alomone laboratories, Jerusalem, Cat. No. ACC-006). The antibody was raised against the intracellular loop connecting domains II and III of the rat CaV2.3

(11) Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection NeuronsThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 16, 2016Gorin M, Tsitoura C, Kahan A, Watznauer K, Drose DR, Arts M, Mathar R, O'Connor S, Hanganu-Opatz IL, Ben-Shaul Y, et al.

(12) Regionally specific expression of high-voltage-activated calcium channels in thalamic nuclei of epileptic and non-epileptic ratsMolecular and cellular neurosciencesJuly 1, 2014Kanyshkova T, Ehling P, Cerina M, Meuth P, Zobeiri M, Meuth SG, Pape HC, Budde T.

(13) Heart failure-induced changes of voltage-gated Ca2+ channels and cell excitability in rat cardiac postganglionic neuronsAmerican journal of physiology. Cell physiologyJanuary 15, 2014Tu H, Liu J, Zhang D, Zheng H, Patel KP, Cornish KG, Wang WZ, Muelleman RL, Li YL.

(14) A quartet of leucine residues in the guanylate kinase domain of CaVβ determines the plasma membrane density of the CaV2.3 channelThe Journal of biological chemistrySeptember 21, 2012Shakeri B, Bourdin B, Demers-Giroux PO, Sauvé R, Parent L.

(15) Modulation/physiology of calcium channel sub-types in neurosecretory terminalsCell CalciumMarch 1, 2012José R. Lemos, Sonia I. Ortiz-Miranda, Adolfo E. Cuadra, Cristina Velázquez-Marrero, Edward E. Custer, Taimur Dad, Govindan DayanithiGainer), neurophysin II (AVP; blue: V15 from SCB) and either an anti-Cav2.1 oranti-Cav2.3 (red: Alomone ACC-001 and ACC-006, respectively). IgGs conjugated to Alexa-Fluor probes were used as secondaries. Images were obtained

(16) Complex distribution patterns of voltage-gated calcium channel α-subunits in the spiral ganglionHearing researchAugust 1, 2011Chen WC, Xue HZ, Hsu YL, Liu Q, Patel S, Davis RL.intracellular loop betweendomain II–III",Methanol,"1:400, 1:100" Cav2.3,"Alomone (Jerusalem, Israel), ACC-006; lot AN-03","Rabbit polyclonal, seq 982-907 aa, intracellular loop betweendomain II–III",4% PFA,1:50 Cav3.1,"Alomone

(17) Decreased calcium channel currents and facilitated epinephrine release in the Ca2+ channel beta3 subunit-null miceBiochemical and biophysical research communicationsApril 9, 2010Ohta T, Ohba T, Suzuki T, Watanabe H, Sasano H, Murakami M.

(18) Anatomical and neurochemical characterization of dopaminergic interplexiform processes in mouse and rat retinasThe Journal of comparative neurologySeptember 10, 2008Witkovsky P, Gábriel R, Krizaj D.purified before use. Rabbit polyclonal antibodies against Cav2.1 (ACC-001), Cav2.2 (ACC-002), and Cav2.3 (ACC-006) were purchased from Alomone (Jerusalem, Israel). The Cav2.1 antibody was raised against the peptide PSSPERAPGREGPYGRE

(19) Involvement of the calcium channel beta3 subunit in olfactory signal transductionBiochemical and biophysical research communicationsApril 20, 2007Shiraiwa T, Kashiwayanagi M, Iijima T, Murakami M.

(20) Modified sympathetic regulation in N-type calcium channel null-mouseBiochemical and biophysical research communicationsMarch 23, 2007Murakami M, Ohba T, Wu TW, Fujisawa S, Suzuki T, Takahashi Y, Takahashi E, Watanabe H, Miyoshi I, Ono K, et al.

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