Anti-PAK1 + PAK2 + PAK3 (phospho T423) antibody ab2477 from Abcam

Product Specs
ItemAnti-PAK1 + PAK2 + PAK3 (phospho T423) antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab2477
Antibody TypePrimary
ApplicationsELISA, Western blot
ClonalityPolyclonal
HostRabbit
Quantity100 UG
IsotypeIgG
Conjugate/TagUnconjugated
FormatThis antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was first purified against the phosphorylated form of the immunizing peptide. The resultant affinity purified antibody was then cross-adsorbed against the non-phosphorylated form of the immunizing peptide
Concentration1.94 mg/ml
ModificationsPhospho-T423
Gene NamePAK2
ReactivityHuman
TargetPAK1 + PAK2 + PAK3

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington’s Disease: Possible Sex-Dependent SignalingCellular and Molecular NeurobiologyApril 1, 2022Akanksha Baharani, Zelan Wei, William J. Roesler, Darrell D. Mousseau(Danvers, MA). Antibodies recognizing LIMK1 (ab38508), phosphoThr508-LIMK1 (ab95186), phosphoThr423-PAK (ab2477), phosphoSer138-profilin1 (ab215752), phosphoSer1366-ROCK2 (ab228008), phosphoT160-CDK2 (ab194868),

(2) GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex MachineryCell ReportsJuly 28, 2020Lauren V. Albrecht, Nydia Tejeda-Muñoz, Maggie H. Bui, Andrew C. Cicchetto, Daniele Di Biagio, Gabriele Colozza, Ernst Schmid, Stefano Piccolo, Heather R. Christofk, Edward M. De RobertisImmunoblotting was performed with antibodies for total Pak1 (Abcam, ab131522), phospho-Pak (T423) (Abcam, ab2477), and Actin (Abcam, ab8227). Secondary antibodies from Li-Cor (IRDye 680 (926–68072) and IRDye 800 (926–32213),

(3) Targeting Phosphorylation of p21-activated Kinase 1 at Thr423 Induces Cell Cycle Arrest and Apoptosis in Cutaneous T-cell Lymphoma CellsActa Dermato VenereologicaOctober 1, 2019Yimeng Wang, Weiwei Li, Qian Zhang, Xiaoguang Gu, Xinglan He, Yuehua Men, Chunlei ZhangLI-COR Odyssey® Imaging System. The primary antibodies used in this study included anti-pho-PAK1Thr423 (ab2477, Abcam), anti-EGR1 (4153S, Cell Signaling, Technology, USA), anti-BCL-2 (4223S, Cell Signaling Technology),

(4) A new role for cofilin in retinal neovascularizationJournal of cell scienceMarch 15, 2016Raj Kumar, Jagadeesh Janjanam, Nikhlesh K Singh, Gadiparthi N Rao

(5) β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activationWorld Journal of GastroenterologySeptember 14, 2015Jun-Song Liu, Xiang-Ming Che, Shuai Chang, Guang-Lin Qiu, Shi-Cai He, Lin Fan, Wei Zhao, Zheng-Liang Zhang, Shu-Feng Wangand anti-Pak1 antibody (#ab40852) were purchased from Abcam. Anti-phospho-Pak1 (T423) antibody was from Abcam (#ab2477) and KeyGEN BioTECH (#KG11165, Nanjing, China). Anti-phospho-ERK1/2 (Thr202/Tyr204) antibody was from

(6) Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient miceNature communicationsJune 24, 2015Singh NK, Kotla S, Dyukova E, Traylor JG Jr, Orr AW, Chernoff J, Marion TN, Rao GN.obtained from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). Anti-ABCA1 (ab18180) and anti-pPak1 (ab2477) Abs were purchased from Abcam (Cambridge, MA). Anti-Pak1 (2602), anti-Pak2 (2608), anti-Pak3 (2609)

(7) Novel role for p21-activated kinase 2 in thrombin-induced monocyte migrationThe Journal of biological chemistryOctober 25, 2013Gadepalli R, Kotla S, Heckle MR, Verma SK, Singh NK, Rao GN.

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(1)

7/9/2015Excellent antibody to detect phospho-Pak in human cells Raj KumarOur experiment was planned to check the effect of Pak1 knockdown in VEGFA induced Pak1 phosphorylation in Human retinal endothelial cells. Antibody showed its excellent specificity towards pPak1.

Anti-PAK1 + PAK2 + PAK3 (phospho T423) antibody from Abcam

Abcam

Citations (7)

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Anti-PAK1 + PAK2 + PAK3 (phospho T423) antibody from Abcam

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