Anti-UQCRFS1/RISP antibody [5A5] ab14746 from Abcam

Product Specs
ItemAnti-UQCRFS1/RISP antibody [5A5]
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab14746
Antibody TypePrimary
ClonalityMonoclonal
Quantity100 UG
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Clone5A5
HostMouse, Nude mouse
IsotypeIgG2b
Conjugate/TagUnconjugated
FormatNear homogeneity as judged by SDS-PAGE. The antibody was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation
Concentration1 mg/ml
Gene NameUQCRFS1
ReactivityCow, Human, Mouse, Rat
TargetUQCRFS1 / RISP

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Sexual dimorphism in bidirectional SR-mitochondria crosstalk in ventricular cardiomyocytesBasic Research in CardiologyMay 3, 2023Richard T. Clements, Radmila Terentyeva, Shanna Hamilton, Paul M. L. Janssen, Karim Roder, Benjamin Y. Martin, Fruzsina Perger, Timothy Schneider, Zuzana Nichtova, Anindhya S. Das, et al.Human,MilliporeSigma,Cat# HPA016480 Anti-COX IV,Rat and Human,Abcam,Cat# ab16056 Anti-UQCRFS1,Rat and Human,Abcam,Cat# ab14746 Anti-NDUFA9,Rat and Human,Abcam,Cat# ab14713 Anti-Hsp60,"H9C2, Rat and Human",Cell Signaling,Cat#

(2) A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in miceNature communicationsJanuary 25, 2023Kobayashi A, Azuma K, Takeiwa T, Kitami T, Horie K, Ikeda K, Inoue S.dilution), rabbit monoclonal NDUFB8 antibody (ab192878, 1:1000 dilution), mouse monoclonal RISP antibody (ab14746, 1:5000 dilution), rabbit monoclonal ATP5A antibody (ab176569, 1:1000 dilution) and mouse monoclonal

(3) NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster ProteinsCancer discoverySeptember 2, 2022Santana-Codina N, Del Rey MQ, Kapner KS, Zhang H, Gikandi A, Malcolm C, Poupault C, Kuljanin M, John KM, Biancur DE, et al.RRID:AB_2231579, 1:1,000), NDUFS3 (Proteintech, 15066-1-AP, RRID:AB_2151109, 1:1,000), UQCRFS1 (Abcam, ab14746, RRID:AB_301445, 1:1,000), DPYD (NovusBio, NBP2-92308, RRID:AB_2910205, 1:1,000), MAP1LC3B (CST, 3868,

(4) Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing SarcomaMolecular cancer research : MCRJuly 6, 2022Tokarsky EJ, Crow JC, Guenther LM, Sherman J, Taslim C, Alexe G, Pishas KI, Rask G, Justis BS, Kasumova A, et al.Thermo Fisher Scientific (MRPL45–PA5-54778, RRID: AB_2644155), Abcam (COA4–ab105678, RRID: AB_10860894; UQCRFS1–ab14746, RRID: AB_301445; CYC1, ab137757; NDUFS1–ab169540, RRID: AB_2687932; ATP5F1–ab84625, RRID: AB_1859955;

(5) Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondriaCommunications biologyMay 12, 2022Toda T, Ito M, Takeda JI, Masuda A, Mino H, Hattori N, Mohri K, Ohno K.analysis The following specific antibodies were used for Western blot analysis: anti-UQCRFS1 (1:1000 dilution, ab14746, Abcam), anti-NDUFS1 (1:1000, ab169540, Abcam), anti-VDAC1 (1:3000, ab14734, Abcam), OXPHOS cocktail

(6) Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory ChainFrontiers in cell and developmental biologyJanuary 1, 2022Robinson DRL, Hock DH, Muellner-Wong L, Kugapreethan R, Reljic B, Surgenor EE, Rodrigues CHM, Caruana NJ, Stroud DA.Cat# 22229-1-AP, RRID:AB_2879039), UQCRC1 (Abcam Cat# ab110252, RRID:AB_10863633), UQCRFS1 (Abcam Cat# ab14746, RRID:AB_301445), UQCRH (Abcam Cat# ab134949, RRID:AB_2800504), and UQCRQ (Abcam Cat# ab110255, RRID:AB_10865309).

(7) FARS2 deficiency in Drosophila reveals the developmental delay and seizure manifested by aberrant mitochondrial tRNA metabolismNucleic acids researchDecember 16, 2021Fan W, Jin X, Xu M, Xi Y, Lu W, Yang X, Guan MX, Ge W.primary antibodies used include anti-NDUFS3 (1:1000; Abcam, ab14711), anti-UQCRFS1 (1:1000; Abcam, ab14746), anti-CO3 (1:1000; Abcam, ab110259), anti-NDUFS1 (1:1000; Proteintech, 12444-1-AP), anti-ATP5A (1:2000;

(8) γ-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal IschemiaInternational Journal of Molecular SciencesNovember 24, 2021Grazyna Nowak, Judit Megyesicore protein 2 (UQCRC2), and Rieske protein subunits of complex III (Cat #ab110252, #ab14745, and #ab14746, respectively) were supplied by Abcam (Cambridge, MA, USA). Antibodies against β-subunit of F0F1-ATPase

(9) NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediateCell reportsApril 20, 2021D'Angelo L, Astro E, De Luise M, Kurelac I, Umesh-Ganesh N, Ding S, Fearnley IM, Gasparre G, Zeviani M, Porcelli AM, et al.anti-UQCRC2 (Abcam, #ab14745) 1:1000; anti-CYC1 (Proteintech, #10242-1-AP) 1:1000; anti-UQCRFS1 (Abcam, #ab14746) 1:1000; anti-MT-CO1 (Abcam, #ab14705) 1:1000; anti-MT-CO2 (Abcam, #ab110258) 1:1000; anti-TIMMDC1 (homemade,

(10) Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunityNature communicationsApril 9, 2021Lee CQE, Kerouanton B, Chothani S, Zhang S, Chen Y, Mantri CK, Hock DH, Lim R, Nadkarni R, Huynh VT, et al.(Santa Cruz Biotechnology SC-390693; 1:5000), anti-COX4 (ABclonal A10098; 1:4000), anti-UQCRFS1 (Abcam ab14746; 1:2500), anti-UQCRC1 (ABclonal A3339; 1:3000), anti-ATP5A (Santa Cruz Biotechnology SC-136178; 1:5000),

(11) The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolismCell reportsMarch 16, 2021Acoba MG, Alpergin ESS, Renuse S, Fernández-Del-Río L, Lu YW, Khalimonchuk O, Clarke CF, Pandey A, Wolfgang MJ, Claypool SM.monoclonal",Abcam,Cat# ab14745; RRID:AB_2213640 "anti-UQCRFS1 (clone 5A5), mouse monoclonal",Abcam,Cat#ab14746; RRID:AB_301445 "Goat anti-rabbit IgG (H+L), secondary antibody, HRP",Thermo Fisher Scientific,Cat#31460;

(12) Na⁺ controls hypoxic signalling by the mitochondrial respiratory chainNatureOctober 1, 2020Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, et al.anti-Fp70 (459200, Invitrogen), monoclonal anti-NDUFS4 (ab87399, Abcam), monoclonal anti-RISP (UQCRFS1) (ab14746, Abcam), polyclonal anti-MCU (HPA016480, Sigma-Aldrich) and monoclonal anti-α-tubulin (T6199, Sigma).

(13) Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondriaeLifeAugust 17, 2020Nowinski SM, Solmonson A, Rusin SF, Maschek JA, Bensard CL, Fogarty S, Jeong MY, Lettlova S, Berg JA, Morgan JT, et al.monoclonal),Abcam,"#ab14715, RRID:AB_301433","WB: (1:10,000)" Antibody,Anti-UQCRFS1 (mouse monoclonal),Abcam,"#ab14746, RRID:AB_301445",WB: (1:1000) Antibody,Anti-MTCO1 (mouse monoclonal),Abcam,"#ab14705, RRID:AB_2084810",WB:

(14) A salvage pathway maintains highly functional respiratory complex INature communicationsApril 2, 2020Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Höhne MN, Hofsetz E, Becker C, Kaspar S, Giese H, et al.monoclonal anti-ATP5A [15H4C4],Abcam,ab14748,1:1000a 1:2500b Mouse monoclonal anti-UQCRFS1/RISP[5A5],Abcam,ab14746,1:1000a Mouse monoclonal anti-UQCRC1,Mol. Probes,459140,1:1000a 1:2500b Mouse monoclonal anti-COX4L1,Mol.

(15) Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assemblyNature communicationsMarch 11, 2020Zhang S, Reljić B, Liang C, Kerouanton B, Francisco JC, Peh JH, Mary C, Jagannathan NS, Olexiouk V, Tang C, et al.anti-COX4, 1:3000 (AbClonal, A10098); anti-UQCRC2, 1:5000 (Abclonal, A4181); anti-UQCRFS1, 1:2500 (Abcam, Ab14746); anti-UQCRH, 1:2500 (Abcam, ab134949); anti-UQCRB, 1:2000 (Sigma, HPA043060); Anti-MTCYB, 1:2000 (Proteintech,

(16) Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IVThe EMBO journalFebruary 3, 2020Protasoni M, Pérez-Pérez R, Lobo-Jarne T, Harbour ME, Ding S, Peñas A, Diaz F, Moraes CT, Fearnley IM, Zeviani M, et al.anti‐UQCRC1,Abcam,ab110252 Mouse monoclonal anti‐UQCRC2,Abcam,ab14745 Mouse monoclonal anti‐UQCRFS1,Abcam,ab14746 Rabbit polyclonal anti‐CYC1,Proteintech,10242‐1‐AP Mouse monoclonal anti‐UQCRQ,Abcam,ab110255 Rabbit

(17) Increased flux through the mevalonate pathway mediates fibrotic repair without injuryThe Journal of clinical investigationNovember 1, 2019Larson-Casey JL, Vaid M, Gu L, He C, Cai GQ, Ding Q, Davis D, Berryhill TF, Wilson LS, Barnes S, et al.extract (57). Immunoblot analysis. The primary antibodies used were: ATF6 (ab11909, Abcam); Rieske (ab14746, Abcam); GGDPS (MA5-25243, Abcam); p-STAT6, clone 19E2.1 (MABE270, MilliporeSigma), Rac1, clone 23A8

(18) Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivationJournal of Clinical InvestigationSeptember 30, 2019W. Brian Dalton et al.anti-UQCC1 (Sigma-Aldrich, HPA034875), anti-UQCC2 (Sigma-Aldrich, HPA039111), anti-UQCRFS1 (Abcam, ab14746), antiUQCRC1 (Abcam, ab110252), anti-UQCRQ (Abcam, ab110255), antiMUT (Abcam, ab133672), anti-DLST (Abcam,

(19) Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia toleranceNature communicationsSeptember 11, 2019Ikeda K, Horie-Inoue K, Suzuki T, Hobo R, Nakasato N, Takeda S, Inoue S.and western blotting analysis using antibodies for COX7RP (1:1000 dilution)2, RISP (1:5000 dilution, ab14746, Abcam, Cambridge, MA), COX1 (1:5000 dilution, ab14705, Abcam), COX4 (1:3000 dilution, 4844, Cell signaling,

(20) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in DrosophilaNature communicationsJuly 23, 2019Andreazza S, Samstag CL, Sanchez-Martinez A, Fernandez-Vizarra E, Gomez-Duran A, Lee JJ, Tufi R, Hipp MJ, Schmidt EK, Nicholls TJ, et al.mouse anti-Tubulin (Sigma-Aldrich Cat# T6793, RRID:AB_477585, 1:5,000), mouse anti-UQCRFS1 (Abcam Cat# ab14746, RRID:AB_301445; 1:600). Horseradish peroxidase-conjugated secondary antibodies: anti-mouse (Abcam Cat#

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Anti-UQCRFS1/RISP antibody [5A5] from Abcam

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Anti-UQCRFS1/RISP antibody [5A5] from Abcam

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