The Rabbit Anti-PDE11A Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PDE11a. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-PDE11A Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene