Anti-Cytochrome P450 Reductase antibody ab13513 from Abcam

Product Specs
ItemAnti-Cytochrome P450 Reductase antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab13513
Antibody TypePrimary
ClonalityPolyclonal
IsotypeIgG
ApplicationsImmunocytochemistry/ Immunofluorescence, Western blot
HostRabbit
Quantity50 UL
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene Namepor
ReactivityHuman, Rat
TargetCytochrome P450 Reductase

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cellsThe Journal of biological chemistryAugust 1, 2023Lin YC, Cheung G, Zhang Z, Papadopoulos V.anti-TOMM20 mouse mAb (Abcam, #ab56783, 1:1000 dilution), anti-CYP450 reductase (POR) rabbit pAb (Abcam, #ab13513, 1:1000 dilution), and anti-TSPO rabbit pAb (1:1000 dilution, generated according to (66)). The following

(2) The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cellsThe Journal of biological chemistryJuly 1, 2022Lin YC, Cheung G, Porter E, Papadopoulos V.antibeta actin mouse mAb (Abcam; #ab8226, 1:3000 dilution), anti-CYP reductase rabbit pAb (Abcam; #ab13513, 1:1000 dilution), and anti-Myc-tag rabbit mAb (Cell Signaling Technology; #2278S, 1:1000 dilution). ROS

(3) Heterologous expression of high-activity cytochrome P450 in mammalian cellsScientific ReportsDecember 1, 2020Masaki Kumondai, Eiji Hishinuma, Evelyn Marie Gutiérrez Rico, Akio Ito, Yuya Nakanishi, Daisuke Saigusa, Noriyasu Hirasawa, Masahiro HiratsukaCorporation); polyclonal anti-calnexin antibody (Enzo Life Sciences); anti-cytochrome P450 reductase antibody (ab13513) and anti-cytochrome b5 antibody (ab69801) (Abcam, CB, UK); horseradish peroxidase (HRP)-conjugated

(4) A Genome-Wide CRISPR/Cas9 Screen Reveals that Riboflavin Regulates Hydrogen Peroxide Entry into HAP1 CellsmBioAugust 11, 2020Chidawanyika T, Mark KMK, Supattapone S.Western blotting using the following antibodies: anti-cytochrome P450 reductase rabbit polyclonal antibody (ab13513) (Abcam, Cambridge, MA, USA) (1:1,000 dilution in 5% [wt/vol] milk–TBST [Tris-buffered saline with Tween

(5) Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell DeathClinical cancer research : an official journal of the American Association for Cancer ResearchDecember 1, 2019Froeling FEM, Swamynathan MM, Deschênes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito M, Li J, Chang AY, et al.Cell Signaling Technology), JAK2 (3230, Cell Signaling Technology), NQO1 (3187, Cell Signaling Technology), POR (ab13513, Abcam), β-Tubulin (2148, Cell Signaling Technology), Catalase (12980, Cell Signaling Technology) and

(6) Effects and mechanism of amyloid β1-42 on mitochondria in astrocytesMolecular medicine reportsMay 1, 2018Yao Y, Huang JZ, Chen Y, Hu HJ, Tang X, Li X.anti-cleaved caspase-3 (9661; 1:800; Cell Signaling Technology, Inc.) and anti-CPR (rabbit polyclonal IgG; ab13513; 1:1,000; Abcam) primary antibodies at 4°C overnight. Subsequently, membranes were incubated with goat

(7) Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycleReproductive Biology and EndocrinologyDecember 1, 2017Amilton Cesar dos Santos, Alan James Conley, Moacir Franco de Oliveira, Gleidson Benevides Oliveira, Diego Carvalho Viana, Antônio Chaves de Assis Netooxidoreductase (CPR) anti-mouse, rat, sheep, rabbit, guinea pig, hamster, cow, dog, human, pig, monkey (1/200- ab13513, Abcam, Cambridge, MA, USA), and P450c17 (1/200- Dr. Alan J. Conley, UC, Davis, California, USA), for

(8) A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolismNature CommunicationsDecember 1, 2017Mercedes Barzi et al.blot was then blocked in 5% milk, followed by primary antibody incubation. Rabbit anti-Por (Abcam cat# ab13513) or mouse anti-β-actin (Sigma cat# A1978) were diluted 1:1,000 and 1:3,000, respectively (full blots

(9) Steroidogenesis during postnatal testicular development of Galea spixiiReproductionNovember 1, 2017P R S Santos, F D Oliveira, M A M Arroyo, M F Oliveira, P Castelucci, A J Conley, A C Assis NetoAbcam), anti-P450c17 (1:600, goat polyclonal, ab48019, Abcam), anti-CPR (1:500, rabbit polyclonal, ab13513, Abcam). Antisera were diluted in PBS prior to immunolabeling. After incubation with the primary antisera,

(10) In vivo and in vitro studies on the roles of p38 mitogen-activated protein kinase and NADPH-cytochrome P450 reductase in Alzheimer's diseaseExperimental and therapeutic medicineNovember 1, 2017Yao Y, Huang JZ, Chen L, Chen Y, Li X.(Thr180/Tyr182; cat no: 9211; 1:1,000; Cell Signaling Technology, Inc., Danvers, MA, USA) or CPR (cat. no. ab13513; 1:1,000; Abcam, Cambridge, UK). Subsequently, secondary anti-rabbit goat IgG antibodies (cat. no. A16110;

(11) Berberine Activates Aryl Hydrocarbon Receptor but Suppresses CYP1A1 Induction through miR-21-3p Stimulation in MCF-7 Breast Cancer CellsMoleculesOctober 28, 2017Sheng-Nan Lo, Chun-Wei Wang, Yueh-Shieh Chen, Chiung-Chiao Huang, Tian-Shung Wu, Lih-Ann Li, I-Jung Lee, Yune-Fang UengBiotech., Inc. (Dallas, TX, USA). Rabbit polyclonal antibody against rat NADPH-P450 reductase (CPR) (Ab13513), which immunoreacted with human CPR [21], was purchased from Abcam (Cambridge, UK). Rabbit anti-human

(12) Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liverThe Journal of biological chemistryMarch 20, 2015Hemantkumar Chavan, Feng Li, Robert Tessman, Kristen Mickey, Kenneth Dorko, Timothy Schmitt, Sean Kumer, Sumedha Gunewardena, Nilesh Gaikwad, Partha Krishnamurthy

(13) A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in miceOncotargetSeptember 15, 2014Therese Liechtenstein et al.

(14) Heme Oxygenase Isoforms Differ in Their Subcellular Trafficking during Hypoxia and Are Differentially Modulated by Cytochrome P450 ReductasePLoS ONEApril 24, 2012Monika Linnenbaum, Mareike Busker, Jan R. Kraehling, Soenke Behrends

(15) Airway Epithelial Transcription Factor NK2 Homeobox 1 Inhibits Mucous Cell Metaplasia and Th2 InflammationAmerican Journal of Respiratory and Critical Care MedicineAugust 15, 2011Yutaka Maeda, Gang Chen, Yan Xu, Hans Michael Haitchi, Lingling Du, Angela R. Keiser, Peter H. Howarth, Donna E. Davies, Stephen T. Holgate, Jeffrey A. Whitsett

(16) Concomitant mutations in the P450 oxidoreductase and androgen receptor genes presenting with 46,XY disordered sex development and androgenization at adrenarcheThe Journal of clinical endocrinology and metabolismJuly 1, 2010Jan Idkowiak, Ewa M Malunowicz, Vivek Dhir, Nicole Reisch, Maria Szarras-Czapnik, Donna M Holmes, Cedric H L Shackleton, John D Davies, Ieuan A Hughes, Nils Krone, Wiebke Arlt

(17) CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cellsDrug metabolism and disposition: the biological fate of chemicalsJune 1, 2010Louise Sivertsson, Monica Ek, Malin Darnell, Irene Edebert, Magnus Ingelman-Sundberg, Etienne P A Neve

(18) Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testesAnatomia, histologia, embryologiaNovember 1, 2009T Büdefeld, D Jezek, D Rozman, G Majdic

(19) Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principleMolecular pharmacologyMarch 1, 2009Hongbin Dong, Timothy P Dalton, Marian L Miller, Ying Chen, Shigeyuki Uno, Zhanquan Shi, Howard G Shertzer, Seema Bansal, Narayan G Avadhani, Daniel W Nebert

(20) Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acidThe Journal of pharmacology and experimental therapeuticsMarch 1, 2008Wenqi Yang, Venugopal Raju Tuniki, Siddam Anjaiah, J R Falck, Cecilia J Hillard, William B Campbell

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Anti-Cytochrome P450 Reductase antibody from Abcam

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Anti-Cytochrome P450 Reductase antibody from Abcam

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