Description
Product Characteristics: For the quantitative determination of human collagen alpha-1(X) chain (COL10A1) concentrations in serum, plasma, tissue homogenates, cell lysates.
Target Information: This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]