Fig 1: Correlation between relative difference of serum biomarkers and EIT extracted parameters for patients with normal and abnormal concentration of TAU before surgery. (A) Heatmap of correlation coefficient between relative difference of TAU protein and EIT extracted information. Significant correlations can be seen in group of CT1-TAU > 115 pg/mL. (B) The correlation of ΔARVHCA and relative difference of TAU protein between T2 and T1 for patients with CT1-TAU > 115 pg/mL. (C) The correlation of kHCA and relative difference of TAU protein between T2 and T1 for patients with CT1-TAU > 115 pg/mL. (D) The correlation of TARVHP and relative difference of TAU protein between T2 and T1 for patients with CT1-S100B > 115 pg/mL. T2–T1 relative difference between after and before surgery, T3–T1 relative difference between 12 h after and before surgery, T4–T1 relative difference between 24 h after and before surgery, T5–T1 relative difference between 48 h after and before surgery, HCA hypothermic circulatory arrest, ΔARVHCA the difference of average resistivity value before and after HCA phase, kHCA the slope of electrical impedance during HCA phase, MRAIabs maximum of the absolute value of resistivity asymmetric index, TARIabs absolute value of time integral of resistivity asymmetric index, TARVHP time integral of electrical impedance for half flow of perfusion; **means p < 0.01.
Fig 2: Tau Pathology in Brain Samples from CNI and AD Patients. A Braak stages in CNI (I-III) correspond to CNI diagnosis, whereas Braak stages V and VI correspond to AD patients. B Neurofibrillary tangles (NFTs) in AD patients were 168-fold higher (p < 0.001) than those in CNI. C Brain tau levels were similar in CNI and AD brain tissue homogenate (p = 0.408). p values were estimated by Mann–Whitney Rank-Sum test
Supplier Page from Abcam for Human Tau ELISA Kit