Primary Peripheral Blood Mononuclear Cells (PBMC), Normal, Human from ATCC

Product Specs
ItemPrimary Peripheral Blood Mononuclear Cells (PBMC), Normal, Human
CompanyATCC
Price $273.00Supplier Page View Company Product Page
Catalog NumberPCS-800-011
Quantity>= 2.5 x 10^7
TypeCell Biology
SpeciesHomo sapiens
TissueBlood
Cell Type (standardized)Mononuclear Cells
Tissue (standardized)Blood
ApplicationsApplications for use include the study of immunology, infection, cancer, hematology, and t-cell suppression assay
Research Area3D cell culture, Immunology, Toxicology, Immuno-oncology, Cell and gene therapy (CGT) development
Cell Typemononuclear cell
GenderLot specific
Agelot-specific
Diseasenormal
Volume1.0 mL

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Profiling biological effects of microbiome metabolites via machine learningiScienceApril 17, 2026Hong A. Chung, Zachary Fralish, Tiffany Tu, Daniel Reker(PBMC060822AH) was obtained from a male Caucasian (46 years old). The second sample was obtained from ATCC (PCS-800-011, Lot 8032322), from a female Caucasian (72 years old). PBMCs were maintained using RMPI-1640 based Lymph-1

(2) Targeting FN1 to overcome gemcitabine resistance in gallbladder cancer: Mechanistic insights and an iRGD-modified PEG-PLGA nanoparticle delivery strategyMaterials Today BioApril 1, 2026Maojin Tian, Xiangwei Meng, Weiwei Song, Zhengyu Wu, Yang Liu, Xianing Dong, Shuai Ren, Juan Du, Peiqing Zhao+T cell culture in vitro Human CD4+T cells were isolated and enriched from mature lymphocytes (hPBMCs, PCS-800-011, ATCC, USA) using a Human CD4+T Cell Enrichment Kit (8804-6814-74, Thermo Fisher Scientific, USA). hPBMCs

(3) Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With CancerJournal of Cardiovascular PharmacologyApril 1, 2026Vincenzo Quagliariello, Margherita Passariello, Martina Belardo, Assunta Esposito, Miriam Paone, Massimiliano Berretta, Martina Iovine, Matteo Barbato, Maria Laura Canale, Andrea Paccone, et al.allowed to adhere for 16 hours. Peripheral blood mononuclear cells (hPBMCs) were purchased from ATCC (PCS-800-011) and coincubated with cardiomyocytes in the same medium at an effector-to-target (E:T) ratio of 5:1

(4) Bioactivity-guided analysis of Moringa olifera fractionated extracts for potential medical applicationSci RepMarch 24, 2026Nancy G. Banoub, Masarra M. Sakr, Mahmoud M. Tawfick , Shaimaa Fayez, Mohamed M. S. Farag, Khaled M. Aboshanaband cell culture techniques Normal human primary peripheral blood mononuclear cells (PBMCs) (ATCC® PCS-800011™) and normal animal Vero cells derived from the kidney of African green monkey (ATCC® CCL- 81™) were

(5) UVB-induced genotoxic stress activates the DNA damage response and innate immune pathways in sea urchin coelomocytesFrontiers in ImmunologyMarch 19, 2026Riss M. Kell, Margaret K. Weber, Rosa Y. Escalante, Jeffrey C. Silva, Andrea G. Bodnarweekly. 2.2 Challenge of human PBMCs with UVB Human peripheral blood mononuclear cells (PBMCs, ATCC #PCS800-011) were purchased from the American Type Culture Collection (ATCC, Manassas, VA). Immediately prior to

(6) Circulating Cell Type Senescence Signatures Reveal High-Resolution Health Status and Trajectories in Human Longitudinal StudiesmedRxivFebruary 11, 2026Bradley Olinger, Carlos Anerillas, Allison B. Herman, Dimitrios Tsitsipatis, Reema Banarjee, Toshiko Tanaka, Julian Candia, Manolis Maragkakis, Stefania Bandinelli, Keenan A. Walker, et al.Technology, FC-0031), HSKM skeletal myoblasts (Gibco, A12555), PBMC peripheral blood mononuclear cells (ATCC, PCS-800-011), PreAdipo subcutaneous preadipocytes (ATCC, PCS- 210-010), NHO osteoblasts (Lonza, CC-2538), NHA astrocytes

(7) SenCat: Cataloging human cell senescence through multiomic profiling of multiple senescent primary cell typesbioRxivFebruary 11, 2026Carlos Anerillas, Gisela Altés, Katarína Grešová, Dimitrios Tsitsipatis, Krystyna Mazan-Mamczarz, Reema Banarjee, Ana S.G. Cunningham, Martin Salamini-Montemurri, Jen-Hao Yang, Rachel Munk, et al.(FBS) and Promocell skeletal muscle cell growth medium. PBMC peripheral blood mononuclear cells (ATCC, PCS-800–011) were cultured in RPMI 1640 plus 10% FBS. PreAdipo subcutaneous preadipocytes (ATCC, PCS-210–010) were

(8) CD8a antibody-functionalized biomimetic red blood cell membrane ectosomes delivering C646 reverse CD8⁺ T Cell exhaustion via H3K18la histone delactylation in gastric cardia adenocarcinomaJournal of NanobiotechnologyJanuary 29, 2026Zheng Xiang, Xinxin Zhang, Xinlei Liu, Xiaohu Lv, Yubo Hu, Chi Zhang, Chunlei Zou, Anqi Wang, Bo Zhang, Wei Wang, et al.human CD8+ T Cells Human CD8⁺ T cells were isolated from peripheral blood mononuclear cells (hPBMCs, PCS-800–011, ATCC, USA) using the CD8 MicroBead Kit (130–045–201, Miltenyi Biotec, USA). Cell purity was verified

(9) CD44 Targeting of Cisplatin-Loaded Hyaluronic Acid-Modified Mesoporous Silica Nanoparticles for Lung Adenocarcinoma: Synthesis, Characterization, In Vitro and In Vivo EvaluationPharmaceuticsJanuary 28, 2026Cem Güler, S. Sacide Gelen, Ebru Şancı, Aylin Buhur, H. Ece Tıkır, Ayşe Nalbantsoy, Adem Güner, E. İlker Medine, Altuğ Yavaşoğlu, Dilek Odacı, et al.Dulbecco’s Modified Eagle’s Medium (DMEM) Ham’s F12. PBMCs (human primary peripheral blood mononuclear cells, ATCC-PCS-800-011™) were cultured in RPMI-1640 medium. These media contain 10% fetal bovine serum (FBS), 2 mM L-glutamine,

(10) Considerations for the use of targeted fluorescence contrast agents to detect circulating cancer cell populations with diffuse in vivo flow cytometryJournal of Biomedical OpticsJanuary 27, 2026Joshua S. Pace, Grace Matheson, Gauri Malankar, Lei Wang, Melissa H. Wong, Summer L. Gibbs, Mark Niedre(which include dendritic cells, monocytes, and lymphocytes). Peripheral blood mononuclear cells (PBMCs; PCS-800-011; ATCC) were thawed and prepared according to ATCC instructions for in vitro non-specific contrast agent

(11) Design and Development of DNA Damage Chemical Inducers of Proximity (DD-CIP) for Targeted Cancer TherapybioRxivNovember 6, 2025Tian Qiu, Yeuan Ting Lee, Brendan G. Dwyer, Yi Jer Tan, Ting Chen, Bryan A. Romero, Yanlan Wang, Jiehui Deng, Tinghu Zhang, Gerald R. Crabtree, et al.NCI-H3122, NCI-H460, GLC16, NCI-H69, NIH-3T3, DMS79, BJ (human fibroblasts, CRL-2522), MRC-5, human PBMC (PCS-800-011, Lot: 80413251) cells were purchased and verified from the ATCC. NCI-H82 cells were a gift from the

(12) Generation of novel human anti-OX-40 mAbs endowed with different biological properties as tools for cancer therapyFrontiers in ImmunologySeptember 17, 2025Rosa Rapuano Lembo, Margherita Passariello, Lorenzo Manna, Guendalina Froechlich, Martina Belardo, Alfredo Nicosia, Emanuele Sasso, Claudia De LorenzoIsolation of Human Peripheral Blood Mononuclear Cells (hPBMCs) Human PBMCs were purchased from ATCC (PCS-800-011). All tissues used for isolation by ATCC are obtained under informed consent and conform to HIPAA regulations

(13) PARP7 inhibition stabilizes STAT1/STAT2 and relieves experimental autoimmune encephalomyelitis in miceCell reportsAugust 26, 2025Xu J, Yu T, Yue Z, Lu X, Zhang Y, Wang L, Åhrling SS, Smith MR, Li YC, Matthews J, et al.mouse bone marrow cells, and human peripheral blood mononuclear cells (PBMCs) were ordered from ATCC (PCS-800-011) and differentiated into macrophages following the procedures in the method details section below. All

(14) Interferon-stimulated gene screening identifies CCND3 as a host restriction factor against emerging high-pathogenic bandavirusesNature communicationsAugust 26, 2025Xu Z, Jiang Z, Feng K, Zhang H, Shi C, Deng F, Wang H, Ning YJ.Cat#HY-18739) for 48 h for cell differentiation. Human peripheral blood mononuclear cells (PBMCs; ATCC, PCS-800-011) were cultured in RPMI-1640 medium. Mouse Bone Marrow-Derived Macrophages (BMDMs) isolated from the

(15) Considerations for the use of contrast agents with diffuse in vivo flow cytometry to detect circulating cancer cell populationsbioRxivJuly 31, 2025Joshua S. Pace, Grace Matheson, Gauri Malankar, Lei Wang, Melissa H. Wong, Summer L. Gibbs, Mark Niedre(which include dendritic cells, monocytes, and lymphocytes). Peripheral Blood Mononuclear Cells [PBMCs, (PCS-800–011; ATCC)] were thawed and prepared according to ATCC instructions for in vitro non-specific contrast agent

(16) Targeting Hepatic Stellate Cell PD-L1 Alters Liver Inflammation and Fibrosis in CCl4 Liver Injury Mouse ModelCellular and Molecular Gastroenterology and HepatologyJuly 16, 2025Bing Bai, Wenming Bao, Yuanguo Wang, Aurpita Shaha, Tatiana Kisseleva, Lianping He, Liankang Sun, Sofia Jerez, Vijay H. Shah, Xianghu Wang, et al.peripheral blood mononuclear cells (PBMCs) were obtained from American Tissue and Cell Culture (ATCC, PCS-800-011) and cultured with RPMI 1640 medium supplemented with 10% FBS as well. To induce monocyte-to-macrophage

(17) Therapeutic Efficacy of CD34-Derived Allogeneic Dendritic Cells Engineered to Express CD93, CD40L, and CXCL13 in Humanized Mouse Models of Pancreatic CancerVaccinesJuly 12, 2025Huerta-Yepez S, Gonzalez JD, Sheik N, Beraki S, Kathirvel E, Rodriguez-Frandsen A, Chen PC, Sargsyan T, Mahammad S, Dybul MR, et al.USA) supplemented with fetal bovine serum (FBS) to a final concentration of 10%. Human PBMCs (ATCC [PCS-800-011]), T cells (ATCC [PCS-800-016, PCS-800-017]), SNU 423 cells (ATCC [CRL-5971]) and other immune cells

(18) CXCL10-induced regulatory T cells and adenosine signaling promote immunosuppression and progression of epithelial ovarian cancerSci RepJuly 1, 2025Annabelle C. Lin, Jake Moscarelli, Yong-Lian Zhu, Z. Ping Lin, Elena S. Ratnerblood mononuclear cells (PBMCs) from a single healthy donor were purchased from ATCC (catalog number PCS-800-011). AMG487 was purchased from Cayman Chemical and Selleck Chemicals. TAK779 was purchased from Cayman

(19) Obesity and cervical intraepithelial neoplasia: regulation of mitochondrial energy metabolism via the Kisspeptin/GPR54 signaling pathwayCancer MetabJune 18, 2025Jiajia Pan, Yuanyuan Chen, Yan Ye, Peipei Li, Feifei Ni, Haizhen Hetitered. The silencing efficiency of the lentiviral sequences was validated in the PBMC cell line (PCS-800-011, ATCC), with detailed experimental results shown in Table S1 and Figure S1. Subsequently, the sequence

(20) Virus and cell specific HMGB1 secretion and subepithelial infiltrate formation in adenovirus keratitisPLoS PathogMay 14, 2025Amrita Saha, Mohammad Mirazul Islam, Rahul Kumar, Ashrafali Mohamed Ismail, Emanuel Garcia, Rama R. Gullapali, James Chodosh, Jaya Rajaiyainfected at MOI 15 for 12 h with or without FSSE (Biomatik Peptide Synthesis: P5779), and PBMCs (ATCC, PCS-800-011) were added to the bottom of each insert and incubated for 4 h. Viability of the PBMCs was assessed

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Primary Peripheral Blood Mononuclear Cells (PBMC), Normal, Human from ATCC

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Primary Peripheral Blood Mononuclear Cells (PBMC), Normal, Human from ATCC

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