Description
Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. MSC have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. These properties, in combination with their developmental plasticity, have generated tremendous interest because of the potential use of MSC in regenerative medicine. Fetal lung has been identified as a rich source of MSC and studies have shown that MSC can differentiate into neural cells, in addition to their mesenchymal differentiation potential [1]. MSC have also been shown to enhance the engraftment of human umbilical cord blood-derived CD34 hematopoietic cells in immunodeficient mice [2]. Flow cytometric analysis showed that fetal lung MSC express CD13, CD29, CD44, CD90, CD105, CD166, and HLA-ABC. HPMSC from ScienCell Research Laboratories are isolated from human lung tissue. HPMSC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HPMSC are characterized by immunofluorescence with antibodies specific to CD73, CD90 and CD105. HPMSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPMSC are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories. Recommended Medium: It is recommended to use Mesenchymal Stem Cell Medium (MSCM, Cat. #7501) for culturing HPMSC in vitro