Recombinant Human Programmed Cell Death 1, His-tagged PDCD1-822H from Creative BioMart

Product Specs
ItemRecombinant Human Programmed Cell Death 1, His-tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberPDCD1-822H
SpeciesHuman
Source/Expression SystemHuman Cells
Molecular WeightThe recombinant mature human PD1 consists of 154 amino acids and has a calculated molecular mass of 18 kDa. As a result of glycosylation, the rhPD1 migrates as an approximately 38-42 kDa protein in SDS-PAGE
Size1
Purity>90 % as determined by SDS-PAGE
Activity1. Immobilized human PD-1 at 2 µg/ml (100 µl/well) can bind PD-L1 Protein, Human, Recombinant (ECD, hFc Tag), the EC50 of human B7-H1 is 150-600 ng/mL.
2. Immobilized human PD-1 at 2 µg/mL (100 µL/well) can bind Anti-PD1(MDX)-IgG4 Antibody (Nivolumab),the EC50 is 8-60 ng/mL.
3. Labeled biotin to PD-1 Protein, Human, Recombinant (His Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of PD-1 Protein, Human, Recombinant (His Tag), Biotinylated bound to Keytruda was 0.1 nM.
4.Captured Anti-PD1 Mab (Human IgG4) on proA Chip can bind PD1 with an affinity constant of 10.03nM as determined in a SPR assay (Biacore T200).
5.Captured Anti-PD-L1 Mab (Human IgG1) on proA Chip can bind PD-L1 with an affinity constant of 1.381nM as determined in a SPR assay (Biacore T200)
Conjugate/TagHis
Molecule NamePDCD1
Gene NamePDCD1, His tagged (Human)
NCBI Gene AliasesCD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
NCBI Full Gene Nameprogrammed cell death 1

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Recombinant Human Programmed Cell Death 1, His-tagged from Creative BioMart