Description
RSPO1 or R-spondin-1 activates the canonical Wnt pathway through ligand binding to the LGR4-6 receptor, forming a complex with phosphorylated LRP6 and Frizzled receptors. This interaction upregulates target gene expression. Animal-Free RSPO1/R-spondin-1 Protein, Human (243a.a, HEK293, His, SUMO) is the recombinant human-derived animal-FreeRSPO1/R-spondin-1 protein, expressed by HEK293, with N-His, N-SUMO labeled tag. This product is for cell culture use only