M-CSF Protein 416-ML-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemM-CSF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number416-ML-010
SpeciesMouse
Quantity10 ug (also 50 ug, 500 ug)
Molecule NameM-CSF
NCBI Full Gene Namecolony stimulating factor 1 (macrophage)
NCBI Gene AliasesBAP025, Csfm, MCSF, Mhdabap25, PG-M-CSF, op
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 29 kDa, reducing conditions
Theoretical: 26 kDa (monomer)
Brand/TrademarkR&D Systems, a Bio-Techne Brand
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse M-CSF Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expressionEuropean journal of immunologyDecember 1, 2023Zhao L, Song R, Liu Y.

(2) Echinococcus granulosus promotes bone resorption by increasing osteoclasts differentiationActa tropicaDecember 1, 2023Sun H, Wang S, Tan W, Li Y, Ren Q, Liu Y, Huang Y, Shi C, Li J.

(3) Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesisMolecular medicine reportsNovember 1, 2023Kim JA, Lim S, Ihn HJ, Kim JE, Yea K, Moon J, Choi H, Park EK.

(4) Interleukin-10 increases macrophage-mediated chemotherapy resistance via FABP5 signaling in multiple myelomaInternational immunopharmacologyNovember 1, 2023Zhang M, Chen J, Zhang H, Dong H, Yue Y, Wang S.

(5) Obacunone targets macrophage migration inhibitory factor (MIF) to impede osteoclastogenesis and alleviate ovariectomy-induced bone lossJournal of advanced researchNovember 1, 2023He J, Zheng L, Li X, Huang F, Hu S, Chen L, Jiang M, Lin X, Jiang H, Zeng Y, et al.

(6) BAP1 promotes osteoclast function by metabolic reprogrammingNature communicationsSeptember 22, 2023Rohatgi N, Zou W, Li Y, Cho K, Collins PL, Tycksen E, Pandey G, DeSelm CJ, Patti GJ, Dey A, et al.

(7) NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severityNature communicationsSeptember 20, 2023Minns MS, Liboro K, Lima TS, Abbondante S, Miller BA, Marshall ME, Tran Chau J, Roistacher A, Rietsch A, Dubyak GR, et al.

(8) Matrix stiffness regulates osteoclast fate through integrin-dependent mechanotransductionBioactive materialsSeptember 1, 2023Wang X, Ji L, Wang J, Liu C.

(9) Impaired mitophagy induces antimicrobial responses in macrophages infected with Mycobacterium tuberculosisCell & bioscienceAugust 30, 2023Lee J, Lee SA, Son SH, Choi JA, Nguyen TD, Kim J, Son D, Song CH.

(10) Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destructionNature communicationsAugust 3, 2023Shimizu K, Kikuta J, Ohta Y, Uchida Y, Miyamoto Y, Morimoto A, Yari S, Sato T, Kamakura T, Oshima K, et al.

(11) The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone diseaseNature communicationsJuly 17, 2023Fu J, Li S, Ma H, Yang J, Pagnotti GM, Brown LM, Weiss SJ, Mapara MY, Lentzsch S.

(12) Graphene oxide/gallium nanoderivative as a multifunctional modulator of osteoblastogenesis and osteoclastogenesis for the synergistic therapy of implant-related bone infectionBioactive materialsJuly 1, 2023Yang Y, Li M, Zhou B, Jiang X, Zhang D, Luo H.

(13) Polyphyllin VII protects from breast cancer-induced osteolysis by suppressing osteoclastogenesis via c-Fos/NFATc1 signalingInternational immunopharmacologyJuly 1, 2023Yang Q, Guo J, Zheng J, Chen Y, Zou B, Li R, Ding Z, Wang Y, Li L, Chen Z, et al.

(14) Accelerated Bone Loss in Transgenic Mice Expressing Constitutively Active TGF-β Receptor Type IInternational journal of molecular sciencesJune 28, 2023Toejing P, Sakunrangsit N, Pho-On P, Phetkong C, Leelahavanichkul A, Sridurongrit S, Greenblatt MB, Lotinun S.

(15) C3a-C3aR signaling is a novel modulator of skeletal homeostasisBone reportsJune 1, 2023Kuhn MB, VandenBerg HS, Reynolds AJ, Carson MD, Warner AJ, LaRue AC, Novince CM, Hathaway-Schrader JD.

(16) Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophagesJournal of translational medicineMay 22, 2023Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, et al.

(17) Inhibition of NADPH Oxidase (NOX) 2 Mitigates Colitis in Mice with Impaired Macrophage AMPK FunctionBiomedicinesMay 14, 2023Banskota S, Wang H, Kwon YH, Gautam J, Haq S, Grondin J, Steinberg GR, Khan WI.

(18) Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritisProceedings of the National Academy of Sciences of the United States of AmericaMay 9, 2023Stavre Z, Kim JM, Yang YS, Nündel K, Chaugule S, Sato T, Park KH, Gao G, Gravallese EM, Shim JH.FBS. Nonadherent cells were collected and cultured in the presence of M-CSF (20 ng/mL, R&D systems, #416-ML-010) for 24 h to obtain monocytes. Alternatively, cells were differentiated into osteoclasts in the presence

(19) IRAK4 inhibition: an effective strategy for immunomodulating peri-implant osseointegration via reciprocally-shifted polarization in the monocyte-macrophage lineage cellsBMC oral healthMay 8, 2023Zhao J, Li J, Xu A, Xu Y, He F, Mao Y.

(20) Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer developmentScience advancesMay 5, 2023Cheu JW, Chiu DK, Kwan KK, Yang C, Yuen VW, Goh CC, Chui NN, Shen W, Law CT, Li Q, et al.

Write a Review

(1)

11/11/2022Excellent Recombinant Mouse M-CSF Recombinant Protein Lucy LiuWe used this M-CSF protein for mice bone marrow-derived macrophage cell (BMDM) stimulation. This protein works great.
(1)

2/18/2020In Vitro Bioactivity in Cell Culture Joanna PlastiraA good and basic growth factor for microglia cultures.

M-CSF Protein

M-CSF Protein

M-CSF Protein

M-CSF Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (595)

Reviews

M-CSF Protein from R&D Systems, a Bio-Techne Brand

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