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Identify Many Targets In A Small Sample

Nov 27 '06
If you were trying to identify (and quantify) multiple targets in a single sample one at a time, you could end up needing a lot of sample. But that is where multiplexing comes in. With multiplexing technologies, the sample is first incubated with a bead containing an antibody (for peptide or protein detection) or stretch of nucleic acid (for nucleic acid detection) specific to the target. After the appropriate incubation and washing steps, the bead passes in front of 2 lasers: One for bead identification and the other for target quantification. Because the beads are small and the detection is precise, multiple targets (up to 100) can be detected within small volumes of sample (less than 50 ul). While all of the instruments below operate on the same principle, you will find differences in the number and types of samples that can be processed. If you want the flexibility of using your system for multiplex cellular assays, for example, you’ll want to check out BD Biosciences’ system. But if maximizing throughput is your goal, you’ll be more interested in the 100 target capabilities of the other systems, some of which are also automation compatible.

  BD FACSArray bioanalyzer from BD Biosciences Luminex 100 IS System from Luminex Corporation
Company BD Biosciences Luminex Corporation
Item BD FACSArray™ bioanalyzer Luminex 100 IS System
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Description The BD FACSArrayTM bioanalyzer is a new platform for fast and sensitive high-content analysis of proteins in cell biology, immunology, and proteomics.

Capable of both multiplexed bead and cellular assays, the BD FACSArray bioanalyzer is a unique "2 in 1" platform that is easy to-use, yet flexible and sensitive where needed...
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The Luminex 100 IS System is a compact analysis system for the clinical and research laboratory that integrates lasers, optics, fluidics, a controller, advanced digital signal processing and a bar code reader. This powerful, compact lab analysis system includes the Luminex 100, the XY Platform, and the SD...
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Catalog Number Request Info CN-L004-01, CN-S001-01
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