Overview
Allergic airway inflammation (AAI) features airway and peribronchial accumulation of eosinophils and lymphocytes, which infiltrate in response to the cytokines IL-4, IL-5, and IL-13. While type 2 helper T (Th2) cells are clearly important for the development of AAI, it has been reported that natural killer T (NKT) cells and activated memory CD8+ T cells play essential effector roles in AAI. These results call into question the current paradigm that CD4+ helper T cells are the main players in allergic asthma. By Jyoti Das Ph.D., Paul Eynott Ph.D., Luc Van Kaer Ph.D., Yufang Shi Ph.D. and Gobardhan Das Ph.D.
Details
Details of this protocol, NKT Cells And CD8+ T Cells Are Dispensable For T Cell Dependent Allergic Airway Inflammation, are located on a web site other than Biocompare Protocols.