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DNA Synthesis (Oligos - DNA) from Midland Certified Reagent Company
| General Product Information |
| Item |
DNA Synthesis (Oligos - DNA) |
| Company |
Midland Certified Reagent Company |
| Price |
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| Catalog Number |
Request Info |
| Scale |
20 nmol, 50 nmol, 200 nmol, 1 µmol, 10 µmol, mg and gram quantities also available |
| Modifications |
Over 250 modifications available 3', 5' and Internal
1000s of combination
Will synthesisze most all commercially available modifications
Self-made modifications - request information |
| Request Information |
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| More Information |
Company Product Page  |
| Product Description |
Midland has been a leader of synthetic DNA, RNA and oligonucleotides for more than 20 years. We pioneered the use of MALDI-TOF mass spectrometry for quality assurance, a procedure that has become the industry standard for the very best in oligonucleotide synthesis. Guided by this quality commitment, we have designed and built DNA synthesizers which produce a lower gene synthesis error rate than any commercially available instrument today. This enables our customers to build genes, and even whole genomes, directly from oligos with an exceptionally high fidelity. This technique has recently been reported in the Proceedings of the National Academy of Sciences, (US) 100, 15440-15445 (2003).
Another outgrowth of our focus on the quality of our synthesis chemistry is the ability to modify oligonucleotides. Today, we offer over 100 modifications, including fluorophores, quenchers, dual-labeled probes, backbone modifications, degeneracies, molecular beacon probes, and minor nucleotides. To view the complete list click here. While several DNA and RNA modifications can be ordered from this website, many pose technical challenges that we will need to discuss with you before we proceed to manufacture, and for these we ask that you contact us. A printout of the MALDI-TOF mass spectrum is provided at no additional charge with all modified oligonucleotides.
We continue to offer all of the popular purification modalities, such as HPLC and PAGE purification. However, synthesis technology is now sufficiently advanced that for many applications, purification, which would have been essential only a few years ago, is no longer necessary. Thus, for example, genes are constructed from GF-grade (desalted) oligonucleotides without the need for further purification.
We also offer information and sales of popular products such as:
RNA Polymers
DNA Polymers
Amino-Modified Oligos
Thiol-Modified Oligos
And More...
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NOTE: Biocompare disclaims any information on this site. Price information is approximate list price and actual prices may vary.
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1-432-897-0212