BCL11B ELISA kits are immunoassay tools for the measurement of the protein BCL11 transcription factor B, which is encoded by the BCL11B gene in humans. Functionally, this protein is a reported key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. The canonical protein structure is reported to have an amino acid sequence of 894 residues and a mass of 95.5 kDa. It is known to be localized in the nucleus and is reported to be highly expressed in the brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally sumoylated. The BCL11B gene has been associated with the disease, Immunodeficiency. Other alias names for this target include B cell CLL/lymphoma 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein, and B-cell lymphoma/leukemia 11B.
There are BCL11B ELISA kits that can detect a target at concentrations as low as 78 pg/mL and as high as 5000 pg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.