These c-Mpl ELISA kits are immunodetection tools for measuring the levels of c-Mpl in biological samples. c-Mpl is an alias of the human MPL gene, which encodes the protein, MPL proto-oncogene, thrombopoietin receptor. Notably, c-Mpl is known to play a role in the cellular response to hypoxia, among other functions. The MPL protein is 635 amino acid residues in length and 71.2 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is localized to the golgi and cell membrane of the cell. In terms of tissue specificity, it is noted to be expressed at a low level in a large number of cells of hematopoietic origin. This protein is known to be ubiquitinated and glycosylated. Other names for this target antigen include CD110.
The detection range for different c-Mpl ELISA kits can vary, with some assays measuring target concentrations as low as 21.88 pg/mL and as high as 1400 pg/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.