YME1L1 ELISA kits are immunoassay tools for the measurement of the protein YME1 like 1 ATPase, which is encoded by the YME1L1 gene in humans. Functionally, this protein is reported to be an ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region. The canonical protein structure is reported to have an amino acid length of 773 residues, a mass of 86.5 kDa, and is a member of the AAA ATPase protein family; Peptidase M41 protein family. It is known to be localized in the mitochondria and is reported be highly expressed in cardiac and skeletal muscle mitochondria. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved. The YME1L1 gene has been associated with the disease, Optic atrophy. Other alias names for this target include MEG4, OPA11, PAMP, YME1L, ATP-dependent zinc metalloprotease YME1L1, and FTSH.
The detection range for different YME1L1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.