F2RL2 ELISA kits are immunoassay tools for the measurement of the protein coagulation factor II thrombin receptor like 2, which is encoded by the F2RL2 gene in humans. Functionally, this protein is a known receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. The canonical protein structure is reported to have an amino acid length of 374 residues, a mass of 42.5 kDa, and is a member of the G-protein coupled receptor 1 protein family. It is known to be localized in the cell membrane and is reported be highly expressed in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and glycosylated. Other alias names for this target include PAR3, proteinase-activated receptor 3, Coagulation factor II receptor-like 2 (protease-actovated receptor 3), protease-activated receptor 3, thrombin receptor-like 2, and PAR-3.
The detection range for different F2RL2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.